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Silk Biomaterials in Wound Healing: Navigating Challenges and Charting the Future of Regenerative Medicine

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TMS 2024 153rd Annual Meeting & Exhibition Supplemental Proceedings (TMS 2024)

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Abstract

Wound healing and skin regeneration are complex processes crucial for human health, and silk biomaterials have emerged as promising tools in these fields. This article explores recent research, challenges, and prospects in the use of silk-based solutions for wound healing and regenerative medicine. Recent studies highlight silk biomaterials’ potential in promoting wound healing and skin regeneration through materials like hydrogels, dressings, and artificial skin grafts. Silk's unique ability to modulate immune responses balances inflammation and tissue repair, making it invaluable in wound care. However, challenges such as regulatory compliance, infection management, and immunomodulation must be addressed. Bridging the gap between research and clinical application demands rigorous testing and personalized wound care approaches. The future of silk biomaterials in wound healing holds promise, with innovations like advanced formulations, bioactive additives, and immunomodulation on the horizon. Regulatory streamlining will make silk-based solutions globally accessible, revolutionizing wound care and advancing regenerative medicine.

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Authors and Affiliations

  1. Department of Daily Need, Worldwide Healthcare, 100, Textile Mill Road, Benin City, Edo State, Nigeria

    Best Atoe

  2. Atoe Specialist Medical Centre Limited, 54, Atoe Street, Off Adolor Collège Road, Ugbowo, Benin City, Edo State, Nigeria

    Best Atoe

  3. Department of Research Outreach, Rubber Research Institute of Nigeria, PMB 1049, Iyanomo, Benin City, Edo State, Nigeria

    Ikhazuagbe H. Ifijen

  4. Department of Research Operations, Crop Protection Division, Plant Pathology and Microbiology Unit, Rubber Research Institute of Nigeria, Benin City, Edo State, Nigeria

    Igbako Philip Okiemute

  5. Department of Chemistry, University of Benin, Benin City, Edo State, Nigeria

    Okeke I. Emmanuel

  6. Department of Chemistry, Edo State University, Uzairue, Edo State, Nigeria

    Muniratu Maliki

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  1. Best Atoe
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  2. Ikhazuagbe H. Ifijen
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Correspondence to Ikhazuagbe H. Ifijen .

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    Atoe, B., Ifijen, I.H., Okiemute, I.P., Emmanuel, O.I., Maliki, M. (2024). Silk Biomaterials in Wound Healing: Navigating Challenges and Charting the Future of Regenerative Medicine. In: TMS 2024 153rd Annual Meeting & Exhibition Supplemental Proceedings. TMS 2024. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-031-50349-8_78

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