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Seizure: Prophylaxis and Treatment in Acute Brain Injury

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Traumatic Brain Injury

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

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Abstract

Prophylaxis for post-traumatic seizures is a current practice to avoid the morbidity and potential secondary brain injury associated with post-traumatic seizure development. The benefits and efficacy of this strategy must be weighed against the potential harm, cost, and side effects of the anticonvulsants. In this chapter, we will review the historical background for prophylaxis, present the available randomized and non-randomized data, and suggest guidelines for therapy.

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Author information

Authors and Affiliations

  1. LAC+USC Medical Center, Los Angeles, CA, USA

    Rembrandt R. VanDruff & Matthew J. Martin

  2. Ascension Medical Group, Pensacola, FL, USA

    Kyle J. Leneweaver

Authors
  1. Rembrandt R. VanDruff
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  2. Kyle J. Leneweaver
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  3. Matthew J. Martin
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Corresponding author

Correspondence to Rembrandt R. VanDruff .

Editor information

Editors and Affiliations

  1. Dept. Anesthesia & Intensive Care, Pisa University Hospital, Pisa, Italy

    Etrusca Brogi

  2. General, Emergency and Trauma Surgery Deptartment, Pisa University Hospital, PISA, Pisa, Italy

    Federico Coccolini

  3. Surgical Intensive Care Unit, Cedars-Sinai Medical Center, Los Angeles, CA, USA

    Eric J. Ley

  4. Department of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Alex Valadka

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VanDruff, R.R., Leneweaver, K.J., Martin, M.J. (2024). Seizure: Prophylaxis and Treatment in Acute Brain Injury. In: Brogi, E., Coccolini, F., Ley, E.J., Valadka, A. (eds) Traumatic Brain Injury. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-031-50117-3_24

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  • DOI: https://doi.org/10.1007/978-3-031-50117-3_24

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-031-50117-3

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