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Bone Tumors

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Musculoskeletal Imaging

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Abstract

In which we learn to judge if a bone tumor is benign or aggressive in appearance.

There are important characteristics of a bone lesion, which will help you make this determination. Is the lesion geographic or non-geographic? Is there a narrow zone of transition or a wide zone of transition? Geography is a key factor. We must know where a bone tumor is located. Is it in the epiphysis, diaphysis, or metaphysis? Is it centrally located, eccentrically located, or cortically based? Each answer will narrow the list of possibilities. Often the diagnosis is clear with only the use of a humble radiograph.

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Bibliography

  1. Wenaden AE, Szyszko TA, Saifuddin A. Imaging of periosteal reactions associated with focal lesions of bone. Clin Radiol. 2005;60(4):439–56.

    Article  CAS  PubMed  Google Scholar 

  2. Miller TT. Bone tumors and tumorlike conditions: analysis with conventional radiography. Radiology. 2008;246(3):662–74.

    Article  PubMed  Google Scholar 

  3. Chen EM, Masih S, Chow K, Matcuk G, Patel D. Periosteal reaction: review of various patterns associated with specific pathology. Contemp Diagn Radiol. 2012;35(17):1–5.

    Article  Google Scholar 

  4. Gemescu IN, Cheerleader KM, Rehnitz C, Weber MA. Imaging features of bone tumors: conventional radiographs and MR imaging correlation. Magn Reson Imaging Clin. 2019;27(4):753–67.

    Article  Google Scholar 

  5. Simon MA, Finn HA. Diagnostic strategy for bone and soft-tissue tumors. JBJS. 1993;75(4):622–31.

    Article  CAS  Google Scholar 

  6. Campanacci M, Mercuri M, Gasbarrini A, Campanacci L. The value of imaging in the diagnosis and treatment of bone tumors. Eur J Radiol. 1998;1(27):S116–22.

    Article  Google Scholar 

  7. Giudici MA, Moser RP Jr, Kransdorf MJ. Cartilaginous bone tumors. Radiol Clin N Am. 1993;31(2):237–59.

    Article  CAS  PubMed  Google Scholar 

  8. Adler CP, Kozlowski K. Primary bone tumors and tumorous conditions in children: pathologic and radiologic diagnosis. Springer Science & Business Media; 2012.

    Google Scholar 

  9. Motamedi K, Seeger LL. Benign bone tumors. Radiol Clin. 2011;49(6):1115–34.

    Article  Google Scholar 

  10. Shah JN, Cohen HL, Choudhri AF, Gupta S, Miller SF. Pediatric benign bone tumors: what does the radiologist need to know?: pediatric imaging. Radiographics. 2017;37(3):1001–2.

    Article  PubMed  Google Scholar 

  11. Hwang S, Hameed M, Kransdorf M. The 2020 World Health Organization classification of bone tumors: what radiologists should know. Skelet Radiol. 2023;52(3):329–48.

    Article  Google Scholar 

  12. Errani C, Tsukamoto S, Mavrogenis AF. Imaging analyses of bone tumors. JBJS Rev. 2020;8(3):e0077.

    Article  PubMed  Google Scholar 

  13. Mehta K, McBee MP, Mihal DC, England EB. Radiographic analysis of bone tumors: a systematic approach. In Seminars in roentgenology 2017 (52, 4, pp. 194-208). WB Saunders

    Google Scholar 

  14. Nomikos GC, Murphey MD, Kransdorf MJ, Bancroft LW, Peterson JJ. Primary bone tumors of the lower extremities. Radiol Clin. 2002;40(5):971–90.

    Article  Google Scholar 

  15. Murphey MD, Choi JJ, Kransdorf MJ, Flemming DJ, Gannon FH. Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics. 2000;20(5):1407–34.

    Article  CAS  PubMed  Google Scholar 

  16. Murphey MD, Robbin MR, McRae GA, Flemming DJ, Temple HT, Kransdorf MJ. The many faces of osteosarcoma. Radiographics. 1997;17(5):1205–31.

    Article  CAS  PubMed  Google Scholar 

  17. Kransdorf MJ, Murphey MD. Osseous tumors. In: Imaging of bone tumors and tumor-like lesions: techniques and applications. Springer; 2009. p. 251–306.

    Chapter  Google Scholar 

  18. Kransdorf MJ, Murphey MD. Giant cell tumor. In: Imaging of bone tumors and tumor-like lesions: techniques and applications. Springer; 2009. p. 321–36.

    Chapter  Google Scholar 

  19. Islinger RB, Kuklo TR, Owens BD, Horan PJ, Choma TJ, Murphey MD, Temple HT. Langerhans’ cell histiocytosis in patients older than 21 years. Clin Orthop Relat Res. 2000;379:231–5.

    Article  Google Scholar 

  20. Flemming DJ, Murphey MD. Enchondroma and chondrosarcoma. Seminars in musculoskeletal radiology 2000 (4, 01, 0059-0072). Thieme Medical Publishers, New York, NY

    Google Scholar 

  21. Murphey MD, Carroll JF, Flemming DJ, Pope TL, Gannon FH, Kransdorf MJ. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004;24(5):1433–66.

    Article  PubMed  Google Scholar 

  22. Robbin MR, Murphey MD. Benign chondroid neoplasms of bone. Seminars in musculoskeletal radiology 2000 (4, 01, 0045-0058). Thieme Medical Publishers, New York, NY

    Google Scholar 

  23. Murphey MD, Andrews CL, Flemming DJ, Temple HT, Smith WS, Smirniotopoulos JG. From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 1996;16(5):1131–58.

    Article  CAS  PubMed  Google Scholar 

  24. Murphey MD, wan Jaovisidha S, Temple HT, Gannon FH, Jelinek JS, Malawer MM. Telangiectatic osteosarcoma: radiologic-pathologic comparison. Radiology. 2003;229(2):545–53.

    Article  PubMed  Google Scholar 

  25. Murphey MD, Kransdorf MJ. Soft tissue tumors. In: Radiologic-pathologic correlations from head to toe: understanding the manifestations of disease. Springer; 2005. p. 743–54.

    Chapter  Google Scholar 

  26. Serfaty A, Samim M. Bone tumors: imaging features of the most common primary osseous malignancies. Radiol Clin. 2022;60(2):221–38.

    Article  Google Scholar 

  27. Parman LM, Murphey MD. Alphabet soup: cystic lesions of bone. Seminars in musculoskeletal radiology 2000(4, 01, 0089-0102). Thieme Medical Publishers, New York, NY

    Google Scholar 

  28. Murphey MD, Sartoris DJ, Quale JL, Pathria MN, Martin NL. Musculoskeletal manifestations of chronic renal insufficiency. Radiographics. 1993;13(2):357–79.

    Article  CAS  PubMed  Google Scholar 

  29. Sobti A, Agrawal P, Agarwala S, Agarwal M. Giant cell tumor of bone-an overview. Arch Bone Jt Surg. 2016;4(1):2.

    PubMed  PubMed Central  Google Scholar 

  30. Chakarun CJ, Forrester DM, Gottsegen CJ, Patel DB, White EA, Matcuk GR Jr. Giant cell tumor of bone: review, mimics, and new developments in treatment. Radiographics. 2013;33(1):197–211.

    Article  PubMed  Google Scholar 

  31. Chen W, DiFrancesco LM. Chondroblastoma: an update. Arch Pathol Lab Med. 2017;141(6):867–71.

    Article  CAS  PubMed  Google Scholar 

  32. Kransdorf MJ, Stull MA, Gilkey FW, Moser RP Jr. Osteoid osteoma. Radiographics. 1991;11(4):671–96.

    Article  CAS  PubMed  Google Scholar 

  33. Chai JW, Hong SH, Choi JY, Koh YH, Lee JW, Choi JA, Kang HS. Radiologic diagnosis of osteoid osteoma: from simple to challenging findings. Radiographics. 2010;30(3):737–49.

    Article  PubMed  Google Scholar 

  34. Angtuaco EJ, Fassas AB, Walker R, Sethi R, Barlogie B. Multiple myeloma: clinical review and diagnostic imaging. Radiology. 2004;231(1):11–23.

    Article  PubMed  Google Scholar 

  35. Collins MS, Koyama T, Swee RG, Inwards CY. Clear cell chondrosarcoma: radiographic, computed tomographic, and magnetic resonance findings in 34 patients with pathologic correlation. Skelet Radiol. 2003;32:687–94.

    Article  Google Scholar 

  36. Cottalorda J, Bourelle S. Modern concepts of primary aneurysmal bone cyst. Arch Orthop Trauma Surg. 2007;127:105–14.

    Article  PubMed  Google Scholar 

  37. Van der Naald N, Smeeing DP, Houwert RM, Hietbrink F, Govaert GA, der DV. Brodie's abscess: a systematic review of reported cases. J Bone Jt Infect. 2019;4(1):33–9.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Kransdorf MJ, Moser RP Jr, Gilkey FW. Fibrous dysplasia. Radiographics. 1990;10(3):519–37.

    Article  CAS  PubMed  Google Scholar 

  39. O’Donnell RJ, Springfield DS, Motwani HK, Ready JE, Gebhardt MC, Mankin HJ. Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. JBJS. 1994;76(12):1827–33.

    Article  Google Scholar 

  40. Mravic M, LaChaud G, Nguyen A, Scott MA, Dry SM, James AW. Clinical and histopathological diagnosis of glomus tumor: an institutional experience of 138 cases. Int J Surg Pathol. 2015;23(3):181–8.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Lincoski CJ, Bush DC, Millon SJ. Epidermoid cysts in the hand. J Hand Surg (Eur Vol). 2009;34(6):792–6.

    Article  CAS  PubMed  Google Scholar 

  42. Gould CF, Ly JQ, Lattin GE Jr, Beall DP, Sutcliffe JB III. Bone tumor mimics: avoiding misdiagnosis. Curr Probl Diagn Radiol. 2007;36(3):124–41.

    Article  PubMed  Google Scholar 

  43. Mhuircheartaigh JN, Lin YC, Wu JS. Bone tumor mimickers: a pictorial essay. Indian J Radiol Imaging. 2014;24(03):225–36.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Greenspan A. Bone island (enostosis): current concept—a review. Skelet Radiol. 1995;24:111–5.

    Article  CAS  Google Scholar 

  45. Smith J. Giant bone islands. Radiology. 1973;107(1):35–6.

    Article  CAS  PubMed  Google Scholar 

  46. Brien EW, Mirra JM, Latanza L, Fedenko A, Luck J Jr. Giant bone island of femur. Case report, literature review, and its distinction from low grade osteosarcoma. Skelet Radiol. 1995;24(7):546–50.

    Article  CAS  Google Scholar 

  47. Ihde LL, Forrester DM, Gottsegen CJ, Masih S, Patel DB, Vachon LA, White EA, Matcuk GR Jr. Sclerosing bone dysplasias: review and differentiation from other causes of osteosclerosis. Radiographics. 2011;31(7):1865–82.

    Article  PubMed  Google Scholar 

  48. Mainzer F, Minagi H, Steinbach HL. The variable manifestations of multiple enchondromatosis. Radiology. 1971;99(2):377–88.

    Article  CAS  PubMed  Google Scholar 

  49. Azouz EM, Saigal G, Rodriguez MM, Podda A. Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement. Pediatr Radiol. 2005;35:103–15.

    Article  PubMed  Google Scholar 

  50. Stull MA, Kransdorf MJ, Devaney KO. Langerhans cell histiocytosis of bone. Radiographics. 1992;12(4):801–23.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, UCLA Health, Los Angeles, CA, USA

    Benjamin Plotkin

  2. Radiology and Imaging Consultants An Affiliate of UCHealth, Colorado Springs, CO, USA

    Bennett L. Davis

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  1. Benjamin Plotkin
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Correspondence to Benjamin Plotkin .

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Plotkin, B., Davis, B.L. (2023). Bone Tumors. In: Musculoskeletal Imaging. Springer, Cham. https://doi.org/10.1007/978-3-031-49021-7_5

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  • DOI: https://doi.org/10.1007/978-3-031-49021-7_5

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  • Print ISBN: 978-3-031-49020-0

  • Online ISBN: 978-3-031-49021-7

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