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MR-Guided Radiotherapy in the Pediatric and Adolescent Patient

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A Practical Guide to MR-Linac

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Abstract

Pediatric cancers comprise a heterogeneous group of tumors that can arise anywhere in the body and require specialized care. Pediatric radiation oncologists are taxed with the job of selecting the appropriate treatment for each patient based on the patient’s age, diagnosis, and prognosis, as well as socioeconomic factors that may come into play for families with young children. The use of magnetic-resonance (MR)-guided radiotherapy has revolutionized treatment for many adult cancers. Its application in the pediatric and adolescent population can provide significant benefits in a variety of clinical scenarios. In this chapter, we will explore common pediatric cancer diagnoses and how the use of MR-guided treatment may allow for smaller treatment volumes and optimized sparing of adjacent organs at risk.

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Authors and Affiliations

  1. Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA

    Margaret M. Kozak & John Buatti

  2. Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, USA

    Margaret M. Kozak

  3. Department of Radiation Oncology, Penn State Cancer Institute, Hershey, PA, USA

    Sean Mahase, Bryan Traughber & Mitchell Machtay

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  1. Margaret M. Kozak
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  2. Sean Mahase
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  3. Bryan Traughber
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  4. Mitchell Machtay
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  5. John Buatti
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Correspondence to Margaret M. Kozak .

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Editors and Affiliations

  1. Department of Radiation Oncology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Indra J. Das

  2. Department of Advanced Radiation Oncology, Ospedale Sacro Cuore Don Calabria, Negrar di Valpolicella, Verona, Italy

    Filippo Alongi

  3. Department of Radiation Oncology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Poonam Yadav

  4. Department of Radiation Oncology, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Bharat B. Mittal

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Kozak, M.M., Mahase, S., Traughber, B., Machtay, M., Buatti, J. (2024). MR-Guided Radiotherapy in the Pediatric and Adolescent Patient. In: Das, I.J., Alongi, F., Yadav, P., Mittal, B.B. (eds) A Practical Guide to MR-Linac. Springer, Cham. https://doi.org/10.1007/978-3-031-48165-9_19

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