Abstract
Suboptimal health (SH) can be defined as the reversible phase of the health-to-disease transition. Consequently, the time-frame between the SH condition onset and related clinically manifested disorder is the operational window to protect the affected person against the disease which he/she is predisposed to. Protection against the health-to-disease transition is a highly comprehensive approach based on predictive diagnostics and treatments tailored to the individualised patient profile. Cost-effectiveness inversely correlates with the suboptimal severity grade and level of care. The corresponding paradigm shift from reactive medical services to advanced predictive, preventive and personalised medicine (PPPM/3PM) in biomedical sciences and daily practice is promoted by the European Association for Predictive, Preventive and Personalised Medicine (EPMA), who is recognised as the world leader in PPPM. PPPM relies on a robust conceptual and technological innovation including multi-professional expertise (researchers, caregivers, educators, technologists, policy-makers, diagnostic and pharmaceutical industry), application of artificial intelligence in medicine, education provided to professionals and general population, active involvement of patient organisation and affected individuals into the doctor–patient collaborative process (participatory medicine), amongst others. Who are the beneficiaries of health-related innovation in the framework of PPPM? The joint position paper released by the EPMA J. in 2021 [1] on behalf of the Suboptimal Health Study Consortium and EPMA stated that below listed medical fields might strongly benefit from the scientific promotion and practical implementation of the SH-related innovation in the framework of 3PM:
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Mental health and physical vitality at any age
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Reproductive health
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Planned pregnancies
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Chrono- and sleep-medicine
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Sport medicine and coached body exercises
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Periodontal health
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Longevity and anti-ageing medicine
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Disease pre-stages
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Anti-stress programmes
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Protection of populations against communicable and non-communicable disorders.
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Abbreviations
- CTD:
-
Connective tissues dysfunction
- EPMA:
-
European Association for Predictive, Preventive and Personalised Medicine
- ET-1:
-
Endothelin-1
- FS:
-
Flammer syndrome
- GAH:
-
Gestational arterial hypertension
- GD:
-
Gestational diabetes
- PE:
-
Preeclampsia
- PPPM/3PM:
-
Predictive, preventive and personalised medicine
- SH:
-
Suboptimal health
References
Wang W, Yan Y, Guo Z, Hou H, Garcia M, Tan X, Anto EO, Mahara G, Zheng Y, Li B, Wang Y, Guo X, Golubnitschaja O (2021) All Around Suboptimal Health. A joint position paper of the Suboptimal Health Study Consortium and European Association for Predictive, Preventive and Personalised Medicine. EPMA J 12(4):1–31. https://doi.org/10.1007/s13167-021-00253-2
Golubnitschaja O, Baban B, Boniolo G, Wang W, Bubnov R, Kapalla M, Krapfenbauer K, Mozaffari M, Costigliola V (2016) Medicine in the early twenty-first century: paradigm and anticipation – EPMA position paper 2016. EPMA J 7:23. https://doi.org/10.1186/s13167-016-0072-4
Koklesova L, Mazurakova A, Samec M, Kudela E, Biringer K, Kubatka P, Golubnitschaja O (2022) Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine. EPMA J 13:177–193. https://doi.org/10.1007/s13167-022-00281-6
Golubnitschaja O (2023) What is the routine mitochondrial health check-up good for? In: Podbielska H, Kapalla M (eds) A holistic approach in the framework of 3P medicine. Book-chapter in the book-volume “Predictive, preventive and personalised medicine: from bench to bedside”, Book Series “Advances in Predictive, Preventive and Personalised Medicine”. Spinger. https://doi.org/10.1007/978-3-031-19564-8
Golubnitschaja O (2023) In: Boyko N, Golubnitschaja O (eds) Microbiome in 3P medicine strategies – the first exploitation guide, Hardcover ISBN: 978-3-031-19563-1; eBook ISBN: 978-3-031-19564-8 in the book series “Advances in Predictive, Preventive and Personalised Medicine”. Springer. https://doi.org/10.1007/978-3-031-19564-8
Evsevieva M, Sergeeva O, Mazurakova A, Koklesova L, Prokhorenko-Kolomoytseva I, Shchetinin E, Birkenbihl C, Costigliola V, Kubatka P, Golubnitschaja O (2022) Pre-pregnancy check-up of maternal vascular status and associated phenotype is crucial for the health of mother and offspring. EPMA J 13(3):351–366. https://doi.org/10.1007/s13167-022-00294-1
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Wang, W., Costigliola, V., Golubnitschaja, O. (2024). Suboptimal Health Management in the Framework of PPP Medicine. In: Wang, W. (eds) All Around Suboptimal Health . Advances in Predictive, Preventive and Personalised Medicine, vol 18. Springer, Cham. https://doi.org/10.1007/978-3-031-46891-9_1
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DOI: https://doi.org/10.1007/978-3-031-46891-9_1
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