Abstract
Early detection of Barrett’s Esophagus (BE), the only known precursor to Esophageal adenocarcinoma (EAC), is crucial for effectively preventing and treating esophageal cancer. In this work, we investigate the potential of geometric Variational Autoencoders (VAEs) to learn a meaningful latent representation that captures the progression of BE. We show that hyperspherical VAE (\(\mathcal {S}\)-VAE ) and Kendall Shape VAE show improved classification accuracy, reconstruction loss, and generative capacity. Additionally, we present a novel autoencoder architecture that can generate qualitative images without the need for a variational framework while retaining the benefits of an autoencoder, such as improved stability and reconstruction quality.
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van Veldhuizen, V., Vadgama, S., de Boer, O., Meijer, S., Bekkers, E.J. (2023). Modeling Barrett’s Esophagus Progression Using Geometric Variational Autoencoders. In: Ali, S., van der Sommen, F., van Eijnatten, M., Papież, B.W., Jin, Y., Kolenbrander, I. (eds) Cancer Prevention Through Early Detection. CaPTion 2023. Lecture Notes in Computer Science, vol 14295. Springer, Cham. https://doi.org/10.1007/978-3-031-45350-2_11
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DOI: https://doi.org/10.1007/978-3-031-45350-2_11
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