Abstract
Pap test is an important screening test for cervical cancer. While evaluating the cytomorphologic features of a Pap smear from the cervix or vagina, it is important to know the normal cytomorphology, benign reactive conditions, and epithelial changes due to infections. This chapter describes the nonneoplastic findings in Pap smear and cytomorphologic features to differentiate them from their mimickers, such as malignancy.
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References
Nayar R, Wilbur DC. The pap test and Bethesda 2014. Cancer Cytopathol. 2015;123(5):271–81.
Makde MM, Sathawane P. Liquid-based cytology: technical aspects. Cytojournal. 2022;14(19):41.
Marcus JZ, Cason P, Downs LS Jr, Einstein MH, Flowers L. The ASCCP cervical cancer screening task force endorsement and opinion on the American Cancer Society updated cervical cancer screening guidelines. J Low Genit Tract Dis. 2021;25(3):187–91.
Kamal M, Topiwala F. Nonneoplastic Cervical Cytology. Cytojournal. 2022;29(19):25.
Pulkkinen J, Huhtala H, Krogerus LA, Hollmén S, Laurila M, Kholová I. Endocervical cytology: inter- and intra-observer variability in conventional pap smears. Acta Cytol. 2022;66(3):206–15.
Bariş Iİ, Keleş AN. Mardin Bölgesinden Verilerle Servikal Sitolojide RIA Etkisine Bir Bakış [A review on the impact of IUD in cervical cytology: Mardin region data]. Turk Patoloji Derg. 2013;29(1):51–7.
Demay RM. The pap test: exfoliative gynecologic cytology. 1st ed. American Society for Clinical Pathology; 2005.
Fitzhugh VA, Heller DS. Significance of a diagnosis of microorganisms on pap smear. J Low Genit Tract Dis. 2008;12(1):40–51.
Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC. Human papillomavirus and cervical cancer. Lancet. 2013;382(9895):889–99.
Schiffman M, Castle PE, Jeronimo J, Rodriguez AC, Wacholder S. Human papillomavirus and cervical cancer. Lancet. 2007;370(9590):890–907.
McBride AA. Mechanisms and strategies of papillomavirus replication. Biol Chem. 2017;398:919–27.
Chernesky M, Freund GG, Hook E 3rd, Leone P, D'Ascoli P, Martens M. Detection of chlamydia trachomatis and Neisseria gonorrhoeae infections in north American women by testing SurePath liquid-based pap specimens in APTIMA assays. J Clin Microbiol. 2007;45(8):2434–8.
Okayama K, Ishii Y, Fujii M, Oda M, Okodo M. Causation of cornflake artifacts: possible association of poor dehydration with drying before mounting in Papanicolaou stain. Diagn Cytopathol. 2022;50(10):E301–5.
Kapila K, Al-Juwaiser A, Haji BE. Crystalline bodies in pap smear: a forgotten entity. Diagn Cytopathol. 2007;35(7):423.
MartÃnez-Girón R, Ribas-Barceló A, GarcÃa-Miralles MT, López-Cabanilles D, Tamargo-Peláez ML, Torre-Bayón C, Fernández-Alvarez L. Airborne fungal spores, pollen grains, and vegetable cells in routine Papanicolaou smears. Diagn Cytopathol. 2004;30(6):381–5.
Rivasi F, Tosi G, Ruozi B, Curatola C. Vegetable cells in Papanicolaou-stained cervical smears. Diagn Cytopathol. 2006;34(1):45–9.
Zreik TG, Rutherford TJ. Psammoma bodies in cervicovaginal smears. Obstet Gynecol. 2001;97(5 Pt 1):693–5.
Szporn A, Chen X, Wu M, Burnstein DE. Collagen balls in cervica-vaginal smears. Acta Cytol. 2005;49(3):262–4.
Thakur A, Sarin H. Hematoidin crystals in pap smear: a revisit. Diagn Cytopathol. 2020;48(1):92.
Abdulla M, Hombal S, Kanbour A, Becich M, Stankovich D, Ries A, Kanbour-Shakir A. Characterizing "blue blobs". Immunohistochemical staining and ultrastructural study. Acta Cytol. 2000;44(4):547–50.
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Sun, T., Gilani, S.M. (2023). Cervical and Vaginal Cytology. In: Gilani, S.M., Cai, G. (eds) Non-Neoplastic Cytology. Springer, Cham. https://doi.org/10.1007/978-3-031-44289-6_3
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DOI: https://doi.org/10.1007/978-3-031-44289-6_3
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