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Cranial Nerve I: Olfactory Nerve

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The Cranial Nerves in Neurology

Abstract

One sentence: The olfactory nerve is the afferent nerve for the sense of smell (it is the only CN where the afferents into the brain do not reach the brain via the thalamus) (Fig. 5.1).

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References

  1. Keir G, Maria NI, Kirsch CFE. Unique imaging findings of neurologic phantosmia following Pfizer-BioNtech COVID-19 vaccination: a case report. Top Magn Reson Imaging. 2021;30(3):133–7.

    Article  PubMed  Google Scholar 

  2. Sonne J, Reddy V, Lopez-Ojeda W. Neuroanatomy, cranial nerve 0 (terminal nerve). Treasure Island, FL: StatPearls; 2022.

    Google Scholar 

  3. Thompson LD. Olfactory neuroblastoma. Head Neck Pathol. 2009;3(3):252–9.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Doty RL. Neurotoxic exposure and impairment of the chemical senses of taste and smell. Handb Clin Neurol. 2015;131:299–324.

    Article  PubMed  Google Scholar 

  5. Attems J, Walker L, Jellinger KA. Olfaction and aging: a mini-review. Gerontology. 2015;61(6):485–90.

    Article  CAS  PubMed  Google Scholar 

  6. Olofsson JK, Ekstrom I, Larsson M, Nordin S. Olfaction and aging: a review of the current state of research and future directions. Iperception. 2021;12(3):20416695211020331.

    PubMed  PubMed Central  Google Scholar 

  7. Reuber M, Al-Din AS, Baborie A, Chakrabarty A. New variant Creutzfeldt-Jakob disease presenting with loss of taste and smell. J Neurol Neurosurg Psychiatry. 2001;71(3):412–3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Kohli P, Soler ZM, Nguyen SA, Muus JS, Schlosser RJ. The Association between olfaction and depression: a systematic review. Chem Senses. 2016;41(6):479–86.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Ferraro S, Convertino I, Leonardi L, Blandizzi C, Tuccori M. Unresolved gustatory, olfactory and auditory adverse drug reactions to antibiotic drugs: a survey of spontaneous reporting to Eudravigilance. Expert Opin Drug Saf. 2019;18(12):1245–53.

    Article  CAS  PubMed  Google Scholar 

  10. Ackerman BH, Kasbekar N. Disturbances of taste and smell induced by drugs. Pharmacotherapy. 1997;17(3):482–96.

    Article  CAS  PubMed  Google Scholar 

  11. Xydakis MS, Albers MW, Holbrook EH, Lyon DM, Shih RY, Frasnelli JA, et al. Post-viral effects of COVID-19 in the olfactory system and their implications. Lancet Neurol. 2021;20(9):753–61.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Konstantinidis I, Tsakiropoulou E, Hahner A, de With K, Poulas K, Hummel T. Olfactory dysfunction after coronavirus disease 2019 (COVID-19) vaccination. Int Forum Allergy Rhinol. 2021;11(9):1399–401.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Hiraga A, Muto M, Kuwabara S. Loss of taste as an initial symptom of a "Facial Diplegia and Paresthesia" Variant of Guillain-Barre Syndrome. Intern Med. 2022;61(19):2957–9.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Han AY, Mukdad L, Long JL, Lopez IA. Anosmia in COVID-19: mechanisms and significance. Chem Senses. 2020;45(6):423–8.

    Article  CAS  Google Scholar 

  15. Wehling E, Naess H, Wollschlaeger D, Hofstad H, Bramerson A, Bende M, et al. Olfactory dysfunction in chronic stroke patients. BMC Neurol. 2015;15:199.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Genter MB, Doty RL. Toxic exposures and the senses of taste and smell. Handb Clin Neurol. 2019;164:389–408.

    Article  PubMed  Google Scholar 

  17. Peter W, Schofield RLD. Smell and taste. In: Doty RL, editor. Handbook of clinical neurology, vol. 164; 2019. p. 2–490.

    Google Scholar 

  18. Christensen IT, Larsson EM, Holm IE, Nielsen OBF, Andersen S. Olfactory testing in consecutive patients referred with suspected dementia. BMC Geriatr. 2017;17(1):129.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Keshavarz P, Haseli S, Yazdanpanah F, Bagheri F, Raygani N, Karimi-Galougahi M. A systematic review of imaging studies in olfactory dysfunction secondary to COVID-19. Acad Radiol. 2021;28(11):1530–40.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Kandemirli SG, Altundag A, Yildirim D, Tekcan Sanli DE, Saatci O. Olfactory bulb MRI and paranasal sinus CT findings in persistent COVID-19 anosmia. Acad Radiol. 2021;28(1):28–35.

    Article  PubMed  Google Scholar 

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Grisold, W., Struhal, W., Grisold, A. (2023). Cranial Nerve I: Olfactory Nerve. In: The Cranial Nerves in Neurology. Springer, Cham. https://doi.org/10.1007/978-3-031-43081-7_5

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  • DOI: https://doi.org/10.1007/978-3-031-43081-7_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-43080-0

  • Online ISBN: 978-3-031-43081-7

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