Skip to main content

Endograft Occlusion

  • Chapter
  • First Online:
Mastering Endovascular Techniques

Abstract

Endograft occlusion is a critical complication that can occur following the placement of an endovascular stent-graft to treat aortic aneurysms or other vascular pathologies. The occlusion of the endograft can result from various factors, including thrombosis, embolization, or the development of graft-related complications. Understanding the mechanisms and risk factors associated with endograft occlusion is essential for optimizing patient outcomes and devising effective prevention and management strategies.

Thrombosis of the endograft may arise due to altered blood flow patterns, pre-existing coagulation disorders, or inadequate anticoagulation therapy. Embolization, on the other hand, can occur when debris or thrombi detach from the aortic wall or the endograft itself, leading to distal obstruction and ischemia.

The assessment of endograft occlusion often involves imaging modalities such as computed tomography angiography (CTA) or duplex ultrasonography. Early detection of occlusive events is crucial to initiate prompt intervention and minimize potential morbidity and mortality. Therapeutic options for endograft occlusion may include endovascular techniques like catheter-directed thrombolysis, mechanical thrombectomy, or angioplasty with stent placement. In some cases, open surgical conversion or graft explantation may be necessary.

Ultimately, the management of endograft occlusion requires a multidisciplinary approach involving interventional radiologists, vascular surgeons, and other healthcare specialists to deliver timely and comprehensive care. Ongoing research and clinical experience in this field will continue to refine treatment strategies, enhance outcomes, and improve the long-term durability of endovascular stent-grafts for aortic and vascular pathologies.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Coulston J, Baigent A, Selvachandran H, Jones S, Torella F, Fisher R. The impact of endovascular aneurysm repair on aortoiliac tortuosity and its use as a predictor of iliac limb complications. J Vasc Surg. 2014;60:585–9. https://doi.org/10.1016/j.jvs.2014.03.279.

    Article  PubMed  Google Scholar 

  2. Moulakakis KG, Antonopoulos CN, Klonaris C, Kakisis J, Lazaris AM, Sfyroeras GS, Mantas G, Mylonas SN, Vasdekis SN, Brountzos EN, et al. Bilateral Endograft limb occlusion after endovascular aortic repair: predictive factors of occurrence. Ann Vasc Surg. 2018;46:299–306. https://doi.org/10.1016/j.avsg.2017.07.019.

    Article  PubMed  Google Scholar 

  3. Inaba Y, Yoshitake A, Hayashi K, Ito T, Hachiya T, Shimizu H. Effect of the terminal aortic diameter on the patency rate of iliac limbs after endovascular aortic repair. Ann Vasc Dis. 2019;12:519–23. https://doi.org/10.3400/avd.oa.19-00080.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Coulston J, Baigent A, Selvachandran H, Jones S, Torella F, Fisher R. Lack of iliac engagement correlates with iliac limb complications following standard EVAR. Vasc Endovasc Surg. 2015;49:201–5. https://doi.org/10.1177/1538574415614403.

    Article  Google Scholar 

  5. Kooijman MA, Schuurmann RCL, Kropman RHJ, Elzefzaf NY, Wille J, Tielliu IFJ, Antoniou GA, de Vries J. Midterm changes in iliac limb apposition after endovascular aortic aneurysm repair. J Cardiovasc Surg. 2023;64:159–66. https://doi.org/10.23736/s0021-9509.23.12582-1.

    Article  Google Scholar 

  6. Bogdanovic M, Stackelberg O, Lindstrom D, Ersryd S, Andersson M, Roos H, Siika A, Jonsson M, Roy J. Limb graft occlusion following endovascular aneurysm repair for infrarenal abdominal aortic aneurysm with the zenith alpha, excluder, and endurant devices: a multicentre cohort study. Eur J Vasc Endovasc Surg. 2021;62:532–9. https://doi.org/10.1016/j.ejvs.2021.05.015.

    Article  PubMed  Google Scholar 

  7. Faure EM, Becquemin JP, Cochennec F, Collaborators E. Predictive factors for limb occlusions after endovascular aneurysm repair. J Vasc Surg. 2015;61:1138–45.e2. https://doi.org/10.1016/j.jvs.2014.11.084.

    Article  PubMed  Google Scholar 

  8. Simmering JA, de Vries M, Haalboom M, Reijnen M, Slump CH, Geelkerken RH. Geometrical changes of the aorta as predictors for thromboembolic events after EVAR with the Anaconda stent-graft. J Endovasc Ther. 2022; https://doi.org/10.1177/15266028221105839.

  9. Coelho A, Nogueira C, Lobo M, Gouveia R, Campos J, Augusto R, Coelho N, Semiao AC, Ribeiro JP, Canedo A. Impact of post-EVAR graft limb kinking in EVAR limb occlusion: Aetiology, early diagnosis, and management. Eur J Vasc Endovasc Surg. 2019;58:681–9. https://doi.org/10.1016/j.ejvs.2019.03.019.

    Article  PubMed  Google Scholar 

  10. Broda M, Eiberg J, Taudorf M, Resch T. Limb graft occlusion after endovascular aneurysm repair with the cook zenith alpha abdominal graft. J Vasc Surg. 2023;77:77. https://doi.org/10.1016/j.jvs.2022.10.026.

    Article  Google Scholar 

  11. Georgiadis GS, Schoretsanitis N, Argyriou C, Nikolopoulos E, Kapoulas K, Georgakarakos EI, Ktenidis K, Lazarides MK. Long-term outcomes of the EndurantTM endograft in patients undergoing endovascular abdominal aortic aneurysm repair. J Vasc Surg. 2023;78:668. https://doi.org/10.1016/j.jvs.2023.04.033.

    Article  PubMed  Google Scholar 

  12. Poublon CG, Holewijn S, van Sterkenburg SMM, Tielliu IFJ, Zeebregts CJ, Reijnen M. Long-term outcome of the GORE EXCLUDER AAA Endoprosthesis for treatment of Infrarenal aortic aneurysms. J Vasc Interv Radiol. 2017;28:637–44. https://doi.org/10.1016/j.jvir.2017.01.012.

    Article  PubMed  Google Scholar 

  13. de Marino PM, Ibraheem A, Gafur N, Mufty H, Schubert N, Verhoeven EL, Katsargyris A. Limb occlusion rate after EVAR with individualized graft limb selection and a Liberal protocol of primary relining. Ann Vasc Surg. 2021;75:445–54. https://doi.org/10.1016/j.avsg.2021.02.046.

    Article  Google Scholar 

  14. Liang NL, Ohki T, Ouriel K, Teigen C, Fry D, Henretta J, Komori K, Kichikawa K, Makaroun MS, Investigators I. Five-year results of the INSPIRATION study for the INCRAFT low-profile endovascular aortic stent graft system. J Vasc Surg. 2021;73:867–873.e2. https://doi.org/10.1016/j.jvs.2020.06.128.

    Article  PubMed  Google Scholar 

  15. Meisenbacher K, Wortmann M, Bischoff MS, Contin P, Bockler D, Geisbusch P. Limb occlusion following endovascular aortic repair: prevention and treatment. Gefasschirurgie. 2019;24:306–12. https://doi.org/10.1007/s00772-019-0537-6.

    Article  Google Scholar 

  16. Draper K, Choi SHJ, Fung A, Baxter K, Taylor D, Chen JC, Misskey J. Evaluation of factors associated with limb thrombus formation after endovascular aortic aneurysm repair. J Vasc Surg. 2023;77:440–5. https://doi.org/10.1016/j.jvs.2022.10.008.

    Article  PubMed  Google Scholar 

  17. Spath P, Pasqui E, Angiletta D, Spinazzola A, Chegai F, Isernia G, Lepidi S, Silingardi R, de Donato G, Gargiulo M, et al. Penumbra indigo percutaneous aspiration Thrombectomy system in the treatment of aortic Endograft iliac limb occlusion: results from an Italian multicentre registry. Eur J Vasc Endovasc Surg. 2023;66:77. https://doi.org/10.1016/j.ejvs.2023.04.008.

    Article  PubMed  Google Scholar 

  18. Han XF, Liu GR, Li TZ, Guo X. Application of the AngioJet ultra Thrombectomy device for the percutaneous mechanical treatment (PMT) of iliac limb occlusion after endovascular aneurysm repair (EVAR). Ann Vasc Surg. 2022;78:161–9. https://doi.org/10.1016/j.avsg.2021.06.016.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alberto Froio .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Mariani, M. et al. (2024). Endograft Occlusion. In: Geroulakos, G., Avgerinos, E., Becquemin, J.P., Makris, G.C., Froio, A. (eds) Mastering Endovascular Techniques. Springer, Cham. https://doi.org/10.1007/978-3-031-42735-0_64

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-42735-0_64

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-42734-3

  • Online ISBN: 978-3-031-42735-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics