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Sex Cord-Stromal Tumors

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Pathology of the Ovary, Fallopian Tube and Peritoneum

Part of the book series: Essentials of Diagnostic Gynecological Pathology ((EDGP))

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Abstract

Sex cord–stromal tumors of the ovary are believed to arise from and/or to contain combinations of the sex cord and stromal components of the developing gonad. During embryogenesis, condensations of subcoelomic epithelium develop into ovarian cortical stroma, granulosa, theca, Sertoli, and Leydig cells in the female. These tumors comprise about 7% of all ovarian malignancies. The fifth edition of the WHO classification divides the sex cord–stromal tumors into three groups: pure stromal tumors, pure sex cord tumors, and mixed sex cord-stromal tumors.

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Authors and Affiliations

  1. University of Chicago, Chicago, IL, USA

    Ricardo R. Lastra

  2. Birmingham Women’s Hospital, Birmingham, UK

    Raji Ganesan

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Correspondence to Raji Ganesan .

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  1. Department of Cellular Pathology, University College London Hospitals NHS Foundation Trust, London, UK

    Nafisa Wilkinson

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Lastra, R.R., Ganesan, R. (2023). Sex Cord-Stromal Tumors. In: Wilkinson, N. (eds) Pathology of the Ovary, Fallopian Tube and Peritoneum. Essentials of Diagnostic Gynecological Pathology. Springer, Cham. https://doi.org/10.1007/978-3-031-39659-5_26

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