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Mycobacterial Infection

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Abstract

Each Monday morning, the fellows and attendings in our division gather over coffee and pastries to discuss the most complicated cases seen over the past week and offer guidance based on the collected experience of the division. Despite not living in an endemic area, talk of mycobacteria (and Mycobacterium tuberculosis in particular) often dominates the conference. Why do these organisms generate so much interest? Mycobacterial infections carry diagnostic and therapeutic challenges. Given the infectiousness of tuberculosis, cases are also infection control challenges. Epidemiology can assist in diagnosis and affect resistance patterns. Treatment itself carries significant toxicities, so decision-making for empiric management is difficult. Mycobacteria are mysterious and complex, especially compared to other bacteria which can typically be treated with source control and antibiotic monotherapy within a few weeks. To understand mycobacteria is to understand the complexities of the ID service!

This chapter will provide an overview of diagnostic and treatment frameworks for tubercular diseases in the format of frequent consult questions, but given the complexity of mycobacterial disease, consultation with local mycobacterial experts is recommended for challenging cases.

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    Alexander M. Tatara

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Tatara, A.M. (2023). Mycobacterial Infection. In: The Infectious Diseases Consult Handbook. Springer, Cham. https://doi.org/10.1007/978-3-031-39474-4_6

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