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Blood Pressure Variability and Heart Failure: Pathophysiological and Clinical Aspects

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Hypertension and Heart Failure

Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

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Abstract

The role of blood pressure variability (BPV) in relation to heart failure (HF) has been supported by some studies in which increasing values of BPV have been associated with a higher frequency of cardiac organ damage and with an increased incidence of HF. In patients already affected by HF, BPV has been associated with an increased risk of cardiovascular events and complications and with a higher incidence of HF hospitalizations. However, the predictive value of BPV in HF patients may depend on the HF phenotype. In its first part, the present chapter will address the role of BPV in promoting cardiac organ damage and development of HF, also discussing potential pathophysiological mechanisms for this association. The second part will address the clinical relevance of BPV in HF patients according to their clinical phenotype. Among other issues we will also deal with the paradoxical relationship reported between BPV and HF with reduced ejection fraction.

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Authors and Affiliations

  1. Department of Cardiology, Istituto Auxologico Italiano, IRCCS, San Luca Hospital, Milan, Italy

    Gianfranco Parati & Juan Eugenio Ochoa

  2. Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy

    Gianfranco Parati

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  1. Gianfranco Parati
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  2. Juan Eugenio Ochoa
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Correspondence to Gianfranco Parati .

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Editors and Affiliations

  1. Carol Davila University of Medicine and Pharmacy, Bucharest, Bucuresti, Romania

    Maria Dorobantu

  2. Department of Pharmacology, Toxicology and Clinical Psychopharmacology Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Victor Voicu

  3. University of Milano-Bicocca, Milano, Italy

    Guido Grassi

  4. Dept of Clinical and Experimental Sci, University of Brescia, Brescia, Italy

    Enrico Agabiti-Rosei

  5. University of Milano-Bicocca, Milano, Italy

    Giuseppe Mancia

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Parati, G., Ochoa, J.E. (2023). Blood Pressure Variability and Heart Failure: Pathophysiological and Clinical Aspects. In: Dorobantu, M., Voicu, V., Grassi, G., Agabiti-Rosei, E., Mancia, G. (eds) Hypertension and Heart Failure. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-031-39315-0_6

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