Skip to main content

Tobacco Prevalence and Treatment

  • Chapter
  • First Online:
Lung Cancer

Part of the book series: Respiratory Medicine ((RM))

  • 357 Accesses

Abstract

Combustible cigarette consumption is at an all-time low in the United States. Still, it remains at epidemic levels, with cigarette smoking a leading cause of disability and premature death in the United States, disproportionately affecting vulnerable populations and minority groups. Sustained abstinence from smoking poses a significant opportunity for positively impacting all-cause mortality, including that from smoking-related cardiac and pulmonary disease and the deadliest cancer known, lung cancer. Nicotine addiction is a complex chronic disease with physical and behavioral afflictions that often lead to relapse. Tobacco treatment guidelines informed by solid evidence promise to enhance the opportunity for successful abstinence from tobacco use. Healthcare providers and others must integrate this science into the effective implementation of pharmacotherapy and behavioral counseling to optimize the effects of such interventions to save lives from tobacco-related diseases. Proactively seeking to understand each patient’s tobacco use and cessation journey through patient-centered care and empathic communication without judgment is vital to building a trusting partnership with patients that accentuates and accelerates successful smoking cessation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. United States Public Health Service. Smoking and health: report of the advisory committee to the surgeon general of the public health service. Washington, DC: U.S. Department of Health, Education, and Welfare; 1964.

    Google Scholar 

  2. Cornelius ME, Loretan CG, Wang TW, Jamal A, Homa DM. Tobacco product use among adults - United States, 2020. MMWR Morb Mortal Wkly Rep. 2022;71(11):397–405. https://doi.org/10.15585/mmwr.mm7111a1.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Garrett BE, Dube SR, Winder C, Caraballo RS. Cigarette smoking—United States, 2006-2008 and 2009-2010. MMWR Suppl. 2013;62(3):81–4.

    PubMed  Google Scholar 

  4. Martell BN, Garrett BE, Caraballo RS. Disparities in adult cigarette smoking—United States, 2002-2005 and 2010-2013. MMWR Morb Mortal Wkly Rep. 2016;65(30):753–8. https://doi.org/10.15585/mmwr.mm6530a1.

    Article  PubMed  Google Scholar 

  5. Jamal A, Agaku IT, O'Connor E, King BA, Kenemer JB, Neff L. Current cigarette smoking among adults—United States, 2005–2013. MMWR Morb Mortal Wkly Rep. 2014;63(47):1108–12.

    PubMed  PubMed Central  Google Scholar 

  6. Graham H. Why social disparities matter for tobacco-control policy. Am J Prev Med. 2009;37(2 Suppl):S183–4. https://doi.org/10.1016/j.amepre.2009.05.007.

    Article  PubMed  Google Scholar 

  7. Department of Health and Human Services. Smoking cessation: a report of the surgeon general. Washington, DC: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2020.

    Google Scholar 

  8. Cdcgov: National and State Tobacco Control Program | Smoking & Tobacco Use | CDC. 2021. https://www.cdc.gov/tobacco/stateandcommunity/tobacco-control/index.htm. Accessed Dec 17 2021.

  9. Drope J, Liber AC, Cahn Z, Stoklosa M, Kennedy R, Douglas CE, et al. Who's still smoking? Disparities in adult cigarette smoking prevalence in the United States. CA Cancer J Clin. 2018;68(2):106–15. https://doi.org/10.3322/caac.21444.

    Article  PubMed  Google Scholar 

  10. Tobacco use among U.S. racial/ethnic minority groups; African Americans, American Indians and Alaska Natives, Asian Americans and Pacific Islanders, Hispanics: a report of the Surgeon General. In: National Center for Chronic Disease P, Health Promotion OoS, Health, editors. Dept. of Health and Human Services, Center for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health 1998.

    Google Scholar 

  11. Babb S, Malarcher A, Schauer G, Asman K, Jamal A. Quitting smoking among adults—United States, 2000–2015. MMWR Morb Mortal Wkly Rep. 2017;65(52):1457–64.

    Article  PubMed  Google Scholar 

  12. Smith PH, Mazure CM, McKee SA. Smoking and mental illness in the U.S. population. Tob Control. 2014;23(e2):e147–53. https://doi.org/10.1136/tobaccocontrol-2013-051466.

    Article  PubMed  Google Scholar 

  13. Eriksen MP, LeMaistre CA, Newell GR. Health hazards of passive smoking. Annu Rev Public Health. 1988;9:47–70. https://doi.org/10.1146/annurev.pu.09.050188.000403.

    Article  CAS  PubMed  Google Scholar 

  14. Truth Initiative—Inspiring Tobacco-Free Lives. 2020.

    Google Scholar 

  15. Cdcgov: D.C. Best practices for comprehensive tobacco control programs, 2014. Atlanta, GA: U.S. Department of Health and Human Services, CDC; 2014. https://www.cdc.gov/tobacco/stateandcommunity/guides/index.htm?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Ftobacco%2Fstateandcommunity%2Fbest_practices%2Findex.htm. Accessed 3 Jan 2022.

    Google Scholar 

  16. Kaiser Family Foundation: Key Facts about the Unisnured Population. 2020. https://www.kff.org/uninsured/issue-brief/key-facts-about-the-uninsured-population/. Accessed 1 Dec 2021.

  17. Institute of Medicine (U.S.). Committee on quality of health Care in America., National Academies Press (U.S.). crossing the quality chasm: a new health system for the 21st century. Washington, DC: National Academy Press; 2001.

    Google Scholar 

  18. Stepanov I. Carcinogens and toxicants in combusted tobacco products and related cancer risks. In: Hecht SSH, editor. Tobacco and cancer: the science and the story. New Jersey: World Scientific; 2022. p. 101–27.

    Chapter  Google Scholar 

  19. U.S. Department of Health & Human Services. Cancer. How tobacco smoke causes disease: the biology and behavioral basis for smoking-attributable disease. Rockville, MD: U.S. Department of Health and Human Services; 2010. p. 221–305.

    Google Scholar 

  20. O'Connor RJ. Tobacco. In: DeVita VT, Lawrence TS, Rosenberg SA, editors. Cancer: principles & practice of oncology. Philadelphia: Wolters Kluwer; 2019. p. 90–8.

    Google Scholar 

  21. Guengerich FP. Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem Res Toxicol. 2001;14(6):611–50. https://doi.org/10.1021/tx0002583.

    Article  CAS  PubMed  Google Scholar 

  22. Boyle P. Tobacco and public health: science and policy. Oxford: Oxford University Press; 2004.

    Google Scholar 

  23. Nishikawa A, Mori Y, Lee IS, Tanaka T, Hirose M. Cigarette smoking, metabolic activation and carcinogenesis. Curr Drug Metab. 2004;5(5):363–73. https://doi.org/10.2174/1389200043335441.

    Article  CAS  PubMed  Google Scholar 

  24. Hecht SS, Szabo E. Fifty years of tobacco carcinogenesis research: from mechanisms to early detection and prevention of lung cancer. Cancer Prev Res (Phila). 2014;7(1):1–8. https://doi.org/10.1158/1940-6207.CAPR-13-0371.

    Article  CAS  PubMed  Google Scholar 

  25. U.S. Department of Health & Human Services. The health consequences of smoking—50 years of Progress: a report of the surgeon general 2014. Executive Summary 2014. https://www.hhs.gov/surgeongeneral/reports-and-publications/tobacco/index.html.

  26. Carson K, Verbiest ME, Crone MR, Brin MP, Esterman AJ, Assendelft WJ, Smith BJ. Training health professionals in smoking cessation. Cochrane Database Syst Rev. 2012;2012(5):CD000214. Accessed 1 Dec 2021.

    PubMed  PubMed Central  Google Scholar 

  27. Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011;365(5):395–409. https://doi.org/10.1056/NEJMoa1102873.

    Article  PubMed  Google Scholar 

  28. Pastorino U, Boffi R, Marchiano A, Sestini S, Munarini E, Calareso G, et al. Stopping smoking reduces mortality in low-dose computed tomography screening participants. J Thorac Oncol. 2016;11(5):693–9. https://doi.org/10.1016/j.jtho.2016.02.011.

    Article  PubMed  Google Scholar 

  29. Wiener RS, Gould MK, Arenberg DA, Au DH, Fennig K, Lamb CR, et al. An official American Thoracic Society/American College of Chest Physicians policy statement: implementation of low-dose computed tomography lung cancer screening programs in clinical practice. Am J Respir Crit Care Med. 2015;192(7):881–91. https://doi.org/10.1164/rccm.201508-1671ST.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Centers for Medicare & Medicaid Services: Screening for Lung Cancer with Low Dose Computed Tomography (LDCT). 2021. https://www.cms.gov/medicare-coverage-database/view/ncacal-decision-memo.aspx?proposed=N&ncaid=304. Accessed 23 Aug 2022.

  31. Parsons A, Daley A, Begh R, Aveyard P. Influence of smoking cessation after diagnosis of early stage lung cancer on prognosis: systematic review of observational studies with meta-analysis. BMJ. 2010;340:b5569. https://doi.org/10.1136/bmj.b5569.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  32. Warren GW, Alberg AJ, Cummings KM, Dresler C. Smoking cessation after a cancer diagnosis is associated with improved survival. J Thorac Oncol. 2020;15(5):705–8. https://doi.org/10.1016/j.jtho.2020.02.002.

    Article  PubMed  Google Scholar 

  33. Toll BA, Brandon TH, Gritz ER, Warren GW, Herbst RS, ASO T, et al. Assessing tobacco use by cancer patients and facilitating cessation: an American Association for Cancer Research policy statement. Clin Cancer Res. 2013;19(8):1941–8. https://doi.org/10.1158/1078-0432.CCR-13-0666.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Aredo JV, Luo SJ, Gardner RM, Sanyal N, Choi E, Hickey TP, et al. Tobacco smoking and risk of second primary lung cancer. J Thorac Oncol. 2021;16(6):968–79. https://doi.org/10.1016/j.jtho.2021.02.024.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Benowitz NL. Nicotine addiction. N Engl J Med. 2010;362(24):2295–303. https://doi.org/10.1056/NEJMra0809890.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Leone FT, Evers-Casey S. Developing a rational approach to tobacco use treatment in pulmonary practice: a review of the biological basis of nicotine addiction. Clin Pulm Med. 2012;19(2):53–61. https://doi.org/10.1097/CPM.0b013e318247cada.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Subramaniyan M, Dani JA. Dopaminergic and cholinergic learning mechanisms in nicotine addiction. Ann N Y Acad Sci. 2015;1349:46–63. https://doi.org/10.1111/nyas.12871.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Zhang T, Zhang L, Liang Y, Siapas AG, Zhou FM, Dani JA. Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine. J Neurosci. 2009;29(13):4035–43. https://doi.org/10.1523/JNEUROSCI.0261-09.2009.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Exley R, Clements MA, Hartung H, McIntosh JM, Cragg SJ. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology. 2008;33(9):2158–66. https://doi.org/10.1038/sj.npp.1301617.

    Article  CAS  PubMed  Google Scholar 

  40. Benowitz NL. Neurobiology of nicotine addiction: implications for smoking cessation treatment. Am J Med. 2008;121(4 Suppl 1):S3–10. https://doi.org/10.1016/j.amjmed.2008.01.015.

    Article  CAS  PubMed  Google Scholar 

  41. Mukhin AG, Kimes AS, Chefer SI, Matochik JA, Contoreggi CS, Horti AG, et al. Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380. J Nucl Med. 2008;49(10):1628–35. https://doi.org/10.2967/jnumed.108.050716.

    Article  PubMed  Google Scholar 

  42. Nashmi R, Xiao C, Deshpande P, McKinney S, Grady SR, Whiteaker P, et al. Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. J Neurosci. 2007;27(31):8202–18. https://doi.org/10.1523/JNEUROSCI.2199-07.2007.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. Cosgrove KP, Batis J, Bois F, Maciejewski PK, Esterlis I, Kloczynski T, et al. beta2-nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking. Arch Gen Psychiatry. 2009;66(6):666–76. https://doi.org/10.1001/archgenpsychiatry.2009.41.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Leone FT, Carlsen KH, Folan P, Latzka K, Munzer A, Neptune E, et al. An official American Thoracic Society research statement: current understanding and future research needs in tobacco control and treatment. Am J Respir Crit Care Med. 2015;192(3):e22–41. https://doi.org/10.1164/rccm.201506-1081ST.

    Article  PubMed  Google Scholar 

  45. Schultz W. Dopamine reward prediction error coding. Dialogues Clin Neurosci. 2016;18(1):23–32.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Hughes JR. Tobacco withdrawal in self-quitters. J Consult Clin Psychol. 1992;60(5):689–97. https://doi.org/10.1037//0022-006x.60.5.689.

    Article  CAS  PubMed  Google Scholar 

  47. Hughes JR, Hatsukami DK, Pickens RW, Svikis DS. Consistency of the tobacco withdrawal syndrome. Addict Behav. 1984;9(4):409–12. https://doi.org/10.1016/0306-4603(84)90043-1.

    Article  CAS  PubMed  Google Scholar 

  48. Ellis C, Jacobs M, Kendall D. The impact of racism, power, privilege, and positionality on communication sciences and disorders research: time to Reconceptualize and seek a pathway to equity. Am J Speech Lang Pathol. 2021;30(5):2032–9. https://doi.org/10.1044/2021_AJSLP-20-00346.

    Article  PubMed  Google Scholar 

  49. FitzGerald C, Hurst S. Implicit bias in healthcare professionals: a systematic review. BMC Med Ethics. 2017;18(1):19. https://doi.org/10.1186/s12910-017-0179-8.

    Article  PubMed  PubMed Central  Google Scholar 

  50. Volkow ND. Stigma and the Toll of addiction. N Engl J Med. 2020;382(14):1289–90. https://doi.org/10.1056/NEJMp1917360.

    Article  PubMed  Google Scholar 

  51. Hamann HA, Ostroff JS, Marks EG, Gerber DE, Schiller JH, Lee SJ. Stigma among patients with lung cancer: a patient-reported measurement model. Psychooncology. 2014;23(1):81–92. https://doi.org/10.1002/pon.3371.

    Article  PubMed  Google Scholar 

  52. Rigney M, Rapsomaniki E, Carter-Harris L, King JC. A 10-year cross-sectional analysis of public, oncologist, and patient attitudes about lung cancer and associated stigma. J Thorac Oncol. 2021;16(1):151–5. https://doi.org/10.1016/j.jtho.2020.09.011.

    Article  PubMed  Google Scholar 

  53. Carter-Harris L. Lung cancer stigma as a barrier to medical help-seeking behavior: practice implications. J Am Assoc Nurse Pract. 2015;27(5):240–5. https://doi.org/10.1002/2327-6924.12227.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Chambers SK, Dunn J, Occhipinti S, Hughes S, Baade P, Sinclair S, et al. A systematic review of the impact of stigma and nihilism on lung cancer outcomes. BMC Cancer. 2012;12:184. https://doi.org/10.1186/1471-2407-12-184.

    Article  PubMed  PubMed Central  Google Scholar 

  55. Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom tolerance questionnaire. Br J Addict. 1991;86(9):1119–27.

    Article  CAS  PubMed  Google Scholar 

  56. Branstetter SA, Muscat JE, Mercincavage M. Time to first cigarette: a potential clinical screening tool for nicotine dependence. J Addict Med. 2020;14(5):409–14. https://doi.org/10.1097/ADM.0000000000000610.

    Article  PubMed  PubMed Central  Google Scholar 

  57. Miller WR, Rollnick S. Motivational interviewing: helping people change. 3rd ed. New York: The Guilford Press; 2013.

    Google Scholar 

  58. United States Preventive Services Task Force: Tobacco Smoking Cessation in Adults, Including Pregnant Persons: Interventions. 2021. https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions. Accessed 1 Nov 2021.

  59. Carr AB, Ebbert J. Interventions for tobacco cessation in the dental setting. Cochrane Database Syst Rev. 2012;2012(6):CD005084. https://doi.org/10.1002/14651858.CD005084.pub3.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Rice VH, Heath L, Livingstone-Banks J, Hartmann-Boyce J. Nursing interventions for smoking cessation. Cochrane Database Syst Rev. 2017;12:CD001188. https://doi.org/10.1002/14651858.CD001188.pub5.

    Article  PubMed  Google Scholar 

  61. Stead LF, Buitrago D, Preciado N, Sanchez G, Hartmann-Boyce J, Lancaster T. Physician advice for smoking cessation. Cochrane Database Syst Rev. 2013;2013(5):CD000165. https://doi.org/10.1002/14651858.CD000165.pub4.

    Article  PubMed  PubMed Central  Google Scholar 

  62. Prochaska JO, DiClemente CC. Stages and processes of self-change of smoking: toward an integrative model of change. J Consult Clin Psychol. 1983;51(3):390–5.

    Article  CAS  PubMed  Google Scholar 

  63. Fiore M, Jaen C, Baker T, Bailey W, Benowitz N, Curry S, et al. Treating tobacco use and dependence: 2008 update. Rockville, MD: U.S. Department of Health and Human Services; 2008.

    Google Scholar 

  64. King B, Dube S, Babb S, McAfee T. Patient-reported recall of smoking cessation interventions from a health professional. Prev Med. 2013;57:715–7.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Sheffer MA, Baker TB, Fraser DL, Adsit RT, McAfee TA, Fiore MC. Fax referrals, academic detailing, and tobacco quitline use: a randomized trial. Am J Prev Med. 2012;42(1):21–8. https://doi.org/10.1016/j.amepre.2011.08.028.

    Article  PubMed  Google Scholar 

  66. Fu SS, Van Ryn M, Sherman SE, Burgess DJ, Noorbaloochi S, Clothier B, et al. Proactive tobacco treatment and population-level cessation: a pragmatic randomized clinical trial. JAMA Intern Med. 2014;174:671–7.

    Article  PubMed  Google Scholar 

  67. Haas J, Linder J, Park E, Gonzalez I, Rigott N, Klinger E, et al. Proactive tobacco cessation outreach to smokers of low socioeconomic status: a randomized clinical trial. JAMA Intern Med. 2015;175:218–26.

    Article  PubMed  PubMed Central  Google Scholar 

  68. Herbst N, Wiener R, Helm E, O'Donnell C, Fitzgerald C, Wong C, et al. Effectiveness of an opt-out electronic helath record-based tobacco treatment consult service at an urban safety net hospital. Chest. 2020;158:1734–41.

    Article  CAS  PubMed  Google Scholar 

  69. U.S. Department of Health and Human Services. Smoking cessation: a report of the surgeon general. Rockville, MD: Public Health Service, Office of the Surgeon General; 2020.

    Google Scholar 

  70. Webb MS, Rodriguez-Esquivel D, Baker EA. Smoking cessation interventions among Hispanics in the United States: a systematic review and mini meta-analysis. Am J Health Promot. 2010;25(2):109–18. https://doi.org/10.4278/ajhp.090123-LIT-25.

    Article  PubMed  Google Scholar 

  71. Bhattacharya A, Vilardaga R, Kientz JA, Munson SA. Lessons from practice: designing tools to facilitate individualized support for quitting smoking. ACM Trans Comput Hum Interact. 2017;2017:3057–70. https://doi.org/10.1145/3025453.3025725.

    Article  PubMed  PubMed Central  Google Scholar 

  72. Klemperer EM, Hughes JR, Solomon LJ, Callas PW, Fingar JR. Motivational, reduction and usual care interventions for smokers who are not ready to quit: a randomized controlled trial. Addiction. 2017;112(1):146–55. https://doi.org/10.1111/add.13594.

    Article  PubMed  Google Scholar 

  73. 2008 PHS Guideline Update Panel La, and Staff. Treating tobacco use and dependence: 2008 update U.S. Public Health Service clinical practice guideline executive summary. Respir Care. 2008;53(9):1217–22.

    Google Scholar 

  74. Beck A. Cognitive therapy: nature and relation to behavior therapy. Behav Ther. 1970;1:184–200.

    Article  Google Scholar 

  75. Butler AC, Chapman JE, Forman EM, Beck AT. The empirical status of cognitive-behavioral therapy: a review of meta-analyses. Clin Psychol Rev. 2006;26(1):17–31. https://doi.org/10.1016/j.cpr.2005.07.003.

    Article  PubMed  Google Scholar 

  76. Stead LF, Carroll AJ, Lancaster T. Group behaviour therapy programmes for smoking cessation. Cochrane Database Syst Rev. 2017;3:CD001007. https://doi.org/10.1002/14651858.CD001007.pub3.

    Article  PubMed  Google Scholar 

  77. Lancaster T, Stead LF. Individual behavioural counselling for smoking cessation. Cochrane Database Syst Rev. 2017;3:CD001292. https://doi.org/10.1002/14651858.CD001292.pub3.

    Article  PubMed  Google Scholar 

  78. Hartmann-Boyce J, Lancaster T, Stead LF. Print-based self-help interventions for smoking cessation. Cochrane Database Syst Rev. 2014;(6):CD001118. https://doi.org/10.1002/14651858.CD001118.pub3.

  79. Whittaker R, McRobbie H, Bullen C, Rodgers A, Gu Y. Mobile phone-based interventions for smoking cessation. Cochrane Database Syst Rev. 2016;4:CD006611. https://doi.org/10.1002/14651858.CD006611.pub4.

    Article  PubMed  Google Scholar 

  80. Sherman SE, Krebs P, York LS, Cummins SE, Kuschner W, Guvenc-Tuncturk S, et al. Telephone care co-ordination for tobacco cessation: randomised trials testing proactive versus reactive models. Tob Control. 2018;27(1):78–82. https://doi.org/10.1136/tobaccocontrol-2016-053327.

    Article  PubMed  Google Scholar 

  81. Hirko KA, Kerver JM, Ford S, Szafranski C, Beckett J, Kitchen C, et al. Telehealth in response to the COVID-19 pandemic: implications for rural health disparities. J Am Med Inform Assoc. 2020;27(11):1816–8. https://doi.org/10.1093/jamia/ocaa156.

    Article  PubMed  PubMed Central  Google Scholar 

  82. Merianos AL, Fevrier B, Mahabee-Gittens EM. Telemedicine for tobacco cessation and prevention to combat COVID-19 morbidity and mortality in rural areas. Front Public Health. 2020;8:598905. https://doi.org/10.3389/fpubh.2020.598905.

    Article  PubMed  Google Scholar 

  83. Matkin W, Ordonez-Mena J, Hartmann-Boyce J. Telephone counseling for smoking cessation. Cochrane Database Syst Rev. 2019;5(5):CD002850.

    PubMed  Google Scholar 

  84. Taylor KL, Hagerman CJ, Luta G, Bellini PG, Stanton C, Abrams DB, et al. Preliminary evaluation of a telephone-based smoking cessation intervention in the lung cancer screening setting: a randomized clinical trial. Lung Cancer. 2017;108:242–6. https://doi.org/10.1016/j.lungcan.2017.01.020.

    Article  PubMed  Google Scholar 

  85. Cobos-Campos R, FernĂ¡ndez A, de Larrinoa A, de Lafuente S, Moriñigo A, Parraza Diez N, Aizpuru BF. Effectiveness of text messaging as an adjuvant to health advice in smoking cessation programs in primary care. A randomized clinical trial. Nicotine Tob Res. 2017;19(8):901–7. https://doi.org/10.1093/ntr/ntw300.

    Article  PubMed  Google Scholar 

  86. Leone FT, Zhang Y, Evers-Casey S, Evins AE, Eakin MN, Fathi J, et al. Initiating pharmacologic treatment in tobacco-dependent adults. An official American Thoracic Society clinical practice guideline. Am J Respir Crit Care Med. 2020;202(2):e5–e31. https://doi.org/10.1164/rccm.202005-1982ST.

    Article  PubMed  PubMed Central  Google Scholar 

  87. Hartwell KJ, Lematty T, McRae-Clark AL, Gray KM, George MS, Brady KT. Resisting the urge to smoke and craving during a smoking quit attempt on varenicline: results from a pilot fMRI study. Am J Drug Alcohol Abuse. 2013;39(2):92–8. https://doi.org/10.3109/00952990.2012.750665.

    Article  PubMed  PubMed Central  Google Scholar 

  88. GĂ³mez-Coronado N, Walker AJ, Berk M, Dodd S. Current and emerging pharmacotherapies for cessation of tobacco smoking. Pharmacotherapy. 2018;38(2):235–58. https://doi.org/10.1002/phar.2073.

    Article  PubMed  Google Scholar 

  89. de Moura FB, McMahon LR. The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice. Psychopharmacology. 2017;234(5):781–92. https://doi.org/10.1007/s00213-016-4514-4.

    Article  CAS  PubMed  Google Scholar 

  90. Hajek P, McRobbie HJ, Myers KE, Stapleton J, Dhanji AR. Use of varenicline for 4 weeks before quitting smoking: decrease in ad lib smoking and increase in smoking cessation rates. Arch Intern Med. 2011;171(8):770–7. https://doi.org/10.1001/archinternmed.2011.138.

    Article  CAS  PubMed  Google Scholar 

  91. Niaura R, Hays JT, Jorenby DE, Leone FT, Pappas JE, Reeves KR, et al. The efficacy and safety of varenicline for smoking cessation using a flexible dosing strategy in adult smokers: a randomized controlled trial. Curr Med Res Opin. 2008;24(7):1931–41. https://doi.org/10.1185/03007990802177523.

    Article  CAS  PubMed  Google Scholar 

  92. Anthenelli RM, Benowitz NL, West R, St Aubin L, McRae T, Lawrence D, et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016;387(10037):2507–20. https://doi.org/10.1016/S0140-6736(16)30272-0.

    Article  CAS  PubMed  Google Scholar 

  93. Stahl SM, Pradko JF, Haight BR, Modell JG, Rockett CB, Learned-Coughlin S. A review of the neuropharmacology of bupropion, a dual norepinephrine and dopamine reuptake inhibitor. Prim Care Companion J Clin Psychiatry. 2004;6(4):159–66.

    PubMed  PubMed Central  Google Scholar 

  94. Fryer JD, Lukas RJ. Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. J Pharmacol Exp Ther. 1999;288(1):88–92.

    CAS  PubMed  Google Scholar 

  95. Stead LF, Koilpillai P, Fanshawe TR, Lancaster T. Combined pharmacotherapy and behavioural interventions for smoking cessation. Cochrane Database Syst Rev. 2016;3:CD008286. https://doi.org/10.1002/14651858.CD008286.pub3.

    Article  PubMed  Google Scholar 

  96. Windle SB, Filion KB, Mancini JG, Adye-White L, Joseph L, Gore GC, et al. Combination therapies for smoking cessation: a hierarchical Bayesian meta-analysis. Am J Prev Med. 2016;51(6):1060–71. https://doi.org/10.1016/j.amepre.2016.07.011.

    Article  PubMed  Google Scholar 

  97. Silverstone PH, Williams R, McMahon L, Fleming R, Fogarty S. Alcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloride. Ann General Psychiatry. 2008;7:11. https://doi.org/10.1186/1744-859X-7-11.

    Article  Google Scholar 

  98. Schnoll RA, Patterson F, Wileyto EP, Heitjan DF, Shields AE, Asch DA, Lerman C. Efficacy of extended duration transdermal nicotine therapy: a randomized trial. Ann Intern Med. 2010;152(3):144–51.

    Article  PubMed  PubMed Central  Google Scholar 

  99. Hajek P, Phillips-Waller A, Przulj D, Pesola F, Myers Smith K, Bisal N, et al. A randomized trial of E-cigarettes versus nicotine-replacement therapy. N Engl J Med. 2019;380(7):629–37. https://doi.org/10.1056/NEJMoa1808779.

    Article  PubMed  Google Scholar 

  100. Hartmann-Boyce J, McRobbie H, Lindson N, Bullen C, Begh R, Theodoulou A, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. 2021;4:CD010216. https://doi.org/10.1002/14651858.CD010216.pub5.

    Article  PubMed  Google Scholar 

  101. Wang RJ, Bhadriraju S, Glantz SA. E-cigarette use and adult cigarette smoking cessation: a meta-analysis. Am J Public Health. 2021;111(2):230–46. https://doi.org/10.2105/AJPH.2020.305999.

    Article  PubMed  PubMed Central  Google Scholar 

  102. Hanewinkel R, Niederberger K, Pedersen A, Unger JB, Galimov A. E-cigarettes and nicotine abstinence: a meta-analysis of randomised controlled trials. Eur Respir Rev. 2022;31(163):210215. https://doi.org/10.1183/16000617.0215-2021.

    Article  PubMed  PubMed Central  Google Scholar 

  103. Krist AH, Davidson KW, Mangione CM, Barry MJ, Cabana M, Caughey AB, et al. Interventions for tobacco smoking cessation in adults, including pregnant persons: U.S. preventive services task force recommendation statement. JAMA. 2021;325(3):265–79. https://doi.org/10.1001/jama.2020.25019.

    Article  PubMed  Google Scholar 

  104. Steinberg MB, Schmelzer AC, Richardson DL, Foulds J. The case for treating tobacco dependence as a chronic disease. Ann Intern Med. 2008;148(7):554–6.

    Article  PubMed  Google Scholar 

  105. Chaiton M, Diemert L, Cohen JE, Bondy SJ, Selby P, Philipneri A, et al. Estimating the number of quit attempts it takes to quit smoking successfully in a longitudinal cohort of smokers. BMJ Open. 2016;6(6):e011045. https://doi.org/10.1136/bmjopen-2016-011045.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Joelle T. Fathi .

Editor information

Editors and Affiliations

Ethics declarations

Hasmeena Kathuria is a section editor for UpToDate (Tobacco Dependence Treatment). Joelle T. Fathi reports no conflict of interest

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Fathi, J.T., Kathuria, H. (2023). Tobacco Prevalence and Treatment. In: MacRosty, C.R., Rivera, M.P. (eds) Lung Cancer. Respiratory Medicine. Humana, Cham. https://doi.org/10.1007/978-3-031-38412-7_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-38412-7_3

  • Published:

  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-031-38411-0

  • Online ISBN: 978-3-031-38412-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics