Skip to main content

Pomelo

  • Chapter
  • First Online:
Recent Advances in Citrus Fruits
  • 221 Accesses

Abstract

Pomelo (Citrus grandis L.), well-known as Chinese grapefruit or shaddock, or chakotra (in Hindi) is belongs to the genus Rutaceae and originated from warm tropical climates in Southeast Asia. The fruit composed of yellowish or greenish skin, white, or pinkish flesh, so commonly classified as white or pink type. It tastes sweet, slight acidic and bitter. Pomelo fruit width ranges in between 10.00 and 30.00 cm and weight range from 1.00 to 2.00 kg dependent on the type of cultivars. The fruit is generally consumed as fruits, juice, as dip with salt mixture, preserved snacks, or used in salad. Major portion of fruit is water, and it is excellent source of amino acid, minerals (like K, P), folic acid, and vitamins like vitamin C, thiamin, riboflavin, and B12, and antioxidants like β-carotene, polyphenols, terpenoids, alkaloids, β-sitosterol, flavonoids (mainly neohesperidin, naringenin, hesperidin, naringin) and essential oils. Citrus fruits, such as Pomelo, have shown enhanced antioxidant capabilities, antimicrobial, anti-inflammatory, hypolipidemic, hypoglycemic, and anticancer effects, additionally, it helps cure skin issues, diabetes, scurvy, and urinary disorders. There is a detailed description of the extraction and application of antioxidant components as well as the health benefits of pomelo juice, peel, and seeds in this section.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Abirami A, Nagarani G, Siddhuraju P (2014) In vitro antioxidant, anti-diabetic, cholinesterase andtyrosinase inhibitory potential of fresh juice from Citrus hystrix and C. maxima fruits. Food Sci Hum Wellness 3:16–25

    Google Scholar 

  • Abirami A, Nagarani G, Siddhuraju P (2015) Hepatoprotective effect of leaf extracts from Citrus hystrix and C. maxima against paracetamol induced liver injury in rats. Food Sci Human Wellness 4:35–41

    Article  Google Scholar 

  • Abobatta WF (2019) Nutritional benefits of citrus fruits. Am J Biomed Sci Res 3:303–306

    Article  Google Scholar 

  • Ajila CM, Leelavathi KUJS, Rao UP (2008) Improvement of dietary fiber content and antioxidant properties in soft dough biscuits with the incorporation of mango peel powder. J Cereal Sci 48:319–326

    Article  CAS  Google Scholar 

  • Ajila CM, Aalami M, Leelavathi K, Rao UP (2010) Mango peel powder: a potential source of antioxidant and dietary fiber in macaroni preparations. Innov Food Sci Emerg Technol 11:219–224

    Article  CAS  Google Scholar 

  • Akiyama S, Katsumata SI, Suzuki K, Ishimi Y, Wu J, Uehara M (2009) Dietary hesperidin exerts hypoglycemic and hypolipidemic effects in streptozotocin-induced marginal type 1 diabetic rats. J Clin Biochem Nutr 46:87–92

    Article  PubMed  PubMed Central  Google Scholar 

  • Ali M, Rumpa NEN, Paul S, Hossen M, Tanvir EM, Hossan T et al (2019) Antioxidant potential, subacute toxicity, and beneficiary effects of methanolic extract of pomelo (Citrus grandis L. Osbeck) in long Evan rats. J Toxicol 2019:2529569

    Article  PubMed  PubMed Central  Google Scholar 

  • Alnaimy A, Gad AE, Mustafa MM, Atta MAA, Basuony HAM (2017) Using of citrus by-products in farm animals feeding. Open Access J Sci 1:58–67

    Article  Google Scholar 

  • Alqu’ezar B, Rodrigo M, Zacar’ıas L (2008) Carotenoid biosynthesis and their regulation in citrus fruits. Tree For Sci Biotechnol 2:23–37

    Google Scholar 

  • Ani PN, Abel HC (2018) Nutrient, phytochemical, and antinutrient composition of Citrus maxima fruit juice and peel extract. Food Sci Nutr 6:653–658

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Anmol RJ, Marium S, Hiew FT, Han WC, Kwan LK, Wong AKY et al (2021) Phytochemical and therapeutic potential of Citrus grandis (L.) Osbeck: a review. J Evid-Based Integr Med 26:2515690X211043741

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Argun ME, Güclü D, Karatas M (2014) Adsorption of reactive blue 114 dye by using a new adsorbent: pomelo peel. J Ind Eng Chem 20:1079–1084

    Article  CAS  Google Scholar 

  • Arias BA, Ramón-Laca L (2005) Pharmacological properties of citrus and their ancient and medieval uses in the Mediterranean region. J Ethnopharmacol 97:89–95

    Article  PubMed  Google Scholar 

  • Athira U (2017) Evaluation of carbohydrate and phenol content of citrus fruits species. Int J Appl Res Nat Prod 3:160–164

    Google Scholar 

  • Basumatary B, Nayak PK, Chandrasekar CM, Nath A, Nayak M, Kesavan RK (2020) Impact of thermo sonication and pasteurization on the physicochemical, microbiological and anti-oxidant properties of pomelo (Citrus maxima) juice. Int J Fruit Sci 20:S2056–S2073

    Article  Google Scholar 

  • Bhattacharya A, Sood P, Citovsky V (2010) The roles of plant phenolics in defense and communication during Agrobacterium and Rhizobium infection. Mol Plant Pathol 11:705–719

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Borah M, Ahmed S, Das S (2012) A comparative study of the antibacterial activity of the ethanolic extracts of Vitex negundo L., Fragaria vesca L., Terminalia arjuna and Citrus maxima. Asian J Pharm Biol Res 2:183–187

    Google Scholar 

  • Brownlee MDM (1995) Advanced protein glycosylation in diabetes and aging. Annu Rev Med 46:223–234

    Article  CAS  PubMed  Google Scholar 

  • Caengprasath N, Ngamukote S, Mäkynen K, Adisakwattana S (2013) The protective effects of pomelo extract (Citrus grandis L. Osbeck) against fructose-mediated protein oxidation and glycation. EXCLI J 12:491–502

    PubMed  PubMed Central  Google Scholar 

  • Camargo CA, Gomes-Marcondes MCC, Wutzki NC, Aoyama H (2012) Naringin inhibits tumor growth and reduces interleukin-6 and tumor necrosis factor α levels in rats with Walker 256 carcinosarcoma. Anticancer Res 32:129–133

    CAS  PubMed  Google Scholar 

  • Chai W, Liu X, Zou J, Zhang X, Li B, Yin T (2015) Pomelo peel modified with acetic anhydride and styrene as new sorbents for removal of oil pollution. Carbohydr Polym 132:245–251

    Article  CAS  PubMed  Google Scholar 

  • Chang SQ, Azlan A (2016) Antioxidant content and activity in different parts of pomelo (Citrus grandis (L.) Osbeck) by-products. Acta Hortic 2016:27–34

    Google Scholar 

  • Chappell LC, Seed PT, Briley AL, Kelly FJ, Lee R, Hunt BJ et al (1999) Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial. Lancet 354:810–816

    Article  CAS  PubMed  Google Scholar 

  • Chaudhari SY, Ruknuddin G, Prajapati P (2016) Ethno medicinal values of citrus genus: a review. Med J DY Patil Univ 9:560

    Article  Google Scholar 

  • Chavan P, Singh AK, Kaur G (2018) Recent progress in the utilization of industrial waste and by-products of citrus fruits: a review. J Food Process Eng 41:e12895

    Article  Google Scholar 

  • Chen D, Niu T, Cai H (2010) Optimizing culture medium for debittering constitutive enzyme naringinase production by Aspergillus oryzae JMU316. Afr J Biotechnol 9:4970–4978

    CAS  Google Scholar 

  • Chen Q, Hu Z, Yao FYD, Liang H (2016) Study 95 of two-stage microwave extraction of essential oil and pectin from pomelo peels. LWT Food Sci Technol 66:538–545

    Article  CAS  Google Scholar 

  • Chen L, Lai Y, Dong L, Kang S, Chen X (2017) Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis. Microb Pathog 113:365–371

    Article  CAS  PubMed  Google Scholar 

  • Chen GW, Lin YH, Lin CH, Jen HC (2018a) Antibacterial activity of emulsified pomelo (Citrus grandis Osbeck) peel oil and water-soluble chitosan on Staphylococcus aureus and Escherichia coli. Molecules 23:840

    Article  PubMed  PubMed Central  Google Scholar 

  • Chen X, Lai Y, Song X, Wu J, Wang L, Zhang H et al (2018b) Polysaccharides from Citrus grandis associate with luteolin relieves chronic pharyngitis by anti-inflammatory via suppressing NF-κB pathway and the polarization of M1 macrophages. Int J Immunopathol Pharmacol 32:2058738418780593

    Article  PubMed  PubMed Central  Google Scholar 

  • Chen Y, Li T, Bai J, Nong L, Ning Z, Hu Z et al (2018c) Chemical composition and antibacterial activity of the essential oil of Citrus maxima (Burm.) Merr. Cv. Shatian Yu. J Biol Act Prod Nat 8:228–233

    CAS  Google Scholar 

  • Cheong MW, Liu SQ, Yeo J, Chionh HK, Pramudya K, Curran P, Yu B (2011) Identification of aroma-active compounds in Malaysian pomelo (Citrus grandis (L.) Osbeck) peel by gas chromatography-olfactometry. J Essent Oil Res 23:34–42

    Google Scholar 

  • Chowdhury MRH, Sagor MAT, Tabassum N, Potol MA, Hossain H, Alam MA (2015) Supplementation of Citrus maxima peel powder prevented oxidative stress, fibrosis, and hepatic damage in carbon tetrachloride (CCl4) treated rats. Evid-Based Complement Altern Med 2015:598179

    Article  Google Scholar 

  • Corciova A, Ciobanu C, Poiata A, Mircea C, Nicolescu A, Drobota M et al (2015) Antibacterial and antioxidant properties of hesperidin: β-cyclodextrin complexes obtained by different techniques. J Incl Phenom Macrocycl Chem 81:71–84

    Article  CAS  Google Scholar 

  • Czech A, Zarycka E, Yanovych D, Zasadna Z, Grzegorczyk I, Kłys S (2020) Mineral content of the pulp and peel of various citrus fruit cultivars. Biol Trace Elem Res 193:555–563

    Article  CAS  PubMed  Google Scholar 

  • Darah I, Taufiq MMJ, Lim SH (2013) Pomelo Citrus grandis (L.) osbeck peel as an economical alternative substrate for fungal pectinase production. Food Sci Biotechnol 22(6):1683–1690

    Article  CAS  Google Scholar 

  • Das S, Borah M, Ahmed S (2013) Antibacterial activity of the ethanolic extract of leaves of Citrus maxima (Burm.) Merr. on Escherichia coli and Pseudomonas aeruginosa. Asian J Pharm Clin Res 6:136–139

    Google Scholar 

  • Das P, Borah PP, Badwaik LS (2018) Transformation of chicken feather keratin and pomelo peel pectin into biodegradable composite film. J Polym Environ 26:2120–2129

    Article  CAS  Google Scholar 

  • Di Mola A, Massa A, De Feo V, Basile A, Pascale M, Aquino RP, De Caprariis P (2017) Effect of citral and citral related compounds on viability of pancreatic and human B-lymphoma cell lines. Med Chem Res 26:631–639

    Article  Google Scholar 

  • Dinesh SS, Hegde K (2016) Antiobesity activity of ethanolic extract of Citrus maxima leaves on cafeteria diet induced and drug induced obese rats. Res J Pharm Technol 9:907–912

    Article  Google Scholar 

  • Ding X, Guo L, Zhang Y, Fan S, Gu M, Lu Y et al (2013) Extracts of pomelo peels prevent high-fat diet-induced metabolic disorders in c57bl/6 mice through activating the PPARα and GLUT4 pathway. PLoS One 8:e77915

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dinkova‐Kostova AT, Talalay P (2008) Direct and indirect antioxidant properties of inducers ofcytoprotective proteins. Mol Nut Food Res 52:S128–S138

    Google Scholar 

  • Dulay RMR, Castro MEGD (2016) Antibacterial and antioxidant activities of three citrus leaves extracts. Der Pharm Lett 8:167–170

    Google Scholar 

  • Ersus S, Cam M (2007) Determination of organic acids, total phenolic content, and antioxidant capacity of sour Citrus aurantium fruits. Chem Nat Compd 43:607–609

    Article  CAS  Google Scholar 

  • Fang J, Cao Z, Song X, Zhang X, Mai B, Wen T et al (2020) Rhoifolin alleviates inflammation of acute inflammation animal models and LPS-induced RAW264. 7 cells via IKKβ/NF-κB signaling pathway. Inflammation 43:2191–2201

    Article  CAS  PubMed  Google Scholar 

  • Feksa DL, Coelho RP, da Costa Güllich AA, Dal Ponte ES, Piccoli JDCE, Manfredini V (2018) Extract of Citrus maxima (pummelo) leaves improve hepatoprotective activity in Wistar rats submitted to the induction of non-alcoholic hepatic steatosis. Biomed Pharmacother 98:338–346

    Article  CAS  PubMed  Google Scholar 

  • Fidrianny IRDA, Sari ELVIRA, Ruslan KOMAR (2016) Phytochemical content and antioxidant activities in different organs of pomelo (Citrus maxima (Burm.)Merr.) using 2, 2-diphenyl-1-picrylhydrazyl and phosphomolybdenum assays. Asian J Pharm Clin Res 9:185–190

    Article  CAS  Google Scholar 

  • Figueiredo AC, Barroso JG, Pedro LG, Scheffer JJ (2008) Factors affecting secondary metabolite production in plants: volatile components and essential oils. Flavour Fragr J 23:213–226

    Article  CAS  Google Scholar 

  • Foo KY, Hameed BH (2011) Microwave assisted preparation of activated carbon from pomelo skin for the removal of anionic and cationic dyes. Chem Eng J 173:385–390

    Article  CAS  Google Scholar 

  • Goh RMV, Lau H, Liu SQ, Lassabliere B, Guervilly R, Sun J et al (2019) Comparative analysis of pomelo volatiles using headspace-solid phase micro-extraction and solvent assisted flavour evaporation. LWT 99:328–345

    Article  Google Scholar 

  • Gonzalez-Mas MC, Rambla JL, Lopez-Gresa MP, Blazquez MA, Granell A (2019) Volatile compounds in citrus essential oils: a comprehensive review. Front Plant Sci 10:1–18

    Article  Google Scholar 

  • Guo C, Yang J, Wei J, Li Y, Xu J, Jiang Y (2003) Antioxidant activities of peel, pulp and seed fractions of common fruits as determined by FRAP assay. Nutr Res 23:1719–1726

    Article  CAS  Google Scholar 

  • Guo JJ, Gao ZP, Xia JL, Ritenour MA, Li GY, Shan Y (2018) Comparative analysis of chemical composition, antimicrobial and antioxidant activity of citrus essential oils from the main cultivated varieties in China. LWT 97:825–839

    Article  Google Scholar 

  • Gupta AK, Yumnam M, Medhi M, Koch P, Chakraborty S, Mishra P (2021a) Isolation and characterization of naringinase enzyme and its application in debittering of Pomelo juice (Citrus grandis): a comparative study with macroporous resin. J Food Process Preserv 45:e15380

    Article  CAS  Google Scholar 

  • Gupta AK, Dhua S, Sahu PP, Abate G, Mishra P, Mastinu A (2021b) Variation in phytochemical, antioxidant and volatile composition of pomelo fruit (Citrus grandis (L.) osbeck) during seasonal growth and development. Plan Theory 10:1941

    CAS  Google Scholar 

  • Gyawali R, Jeon DH, Moon J, Kim H, Song YW, Hyun HB et al (2012) Chemical composition and antiproliferative activity of supercritical extract of Citrus grandis (L.) Osbeck fruits from Korea. J Essent Oil Bear Plants 15:915–925

    Article  Google Scholar 

  • Hameed BH, Mahmoud DK, Ahmad AL (2008) Sorption of basic dye from aqueous solution by pomelo (Citrus grandis) peel in a batch system. Colloids Surf A Physicochem Eng Asp 316:78–84

    Article  CAS  Google Scholar 

  • Haque MN, Saha BK, Karim MR, Bhuiyan MNH (2009) Evaluation of nutritional and physico-chemical properties of several selected fruits in Bangladesh. Bangladesh J Sci Ind Res 44:353–358

    Article  CAS  Google Scholar 

  • Hasegawa S, Ou P, Fong CH, Herman Z, Coggins CW Jr, Atkin DR (1991) Changes in the limonoate A-ring lactone and limonin 17-. beta.-D-glucopyranoside content of navel oranges during fruit growth and maturation. J Agric Food Chem 39:262–265

    Article  CAS  Google Scholar 

  • He W, Li X, Peng Y, He X, Pan S (2019) Anti-oxidant and anti-melanogenic properties of essential oil from peel of pomelo cv. Guan Xi. Molecules 24:242

    Article  PubMed  PubMed Central  Google Scholar 

  • Hosni K, Zahed N, Chrif R, Abid I, Medfei W, Kallel M et al (2010) Composition of peel essential oils from four selected Tunisian Citrus species: evidence for the genotypic influence. Food Chem 123:1098–1104

    Article  CAS  Google Scholar 

  • Hussain K, Wajid A, Babar ME, Anwar Z, Farooqi S, Siddiqa A et al (2019) Production and optimization of pectinase from pomelo by Aspergilliusniger through solid state fermentation. Ann Life Sci 6:21–41

    Google Scholar 

  • Ishihara M, Toda H, Sunagane N, Ohta T (2011) Furanocoumarins contents and cytochrome P450 3A (CYP3A) inhibitory activities of various processed fruit peel products: outflow of 6′, 7′-Dihydroxybergamottin during processing treatment of peel. J Pharm Soc Jpn 131:679–684

    Article  CAS  Google Scholar 

  • Islam A, Tasnin MN, Bari MW, Hossain MI, Islam MA (2021) Vitro antioxidant and in vivo antidiabetic properties of Citrus maxima leaf extracts in alloxan-induced swiss albino diabetic mice. Asian Food Sci J 20:66–79

    Article  Google Scholar 

  • Jang HD, Chang KS, Chang TC, Hsu CL (2010) Antioxidant potentials of buntan pumelo (Citrus grandis Osbeck) and its ethanolic and acetified fermentation products. Food Chem 118:554–558

    Article  CAS  Google Scholar 

  • Jiang CC, Zhang YF, Lin YJ, Chen Y, Lu XK (2019) Illumina® sequencing reveals candidate genes of carotenoid metabolism in three pummelo cultivars (Citrus maxima) with different pulp color. Int J Mol Sci 20:2246

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jing L, Lei Z, Li L, Xie R, Xi W, Guan Y et al (2014) Antifungal activity of citrus essential oils. J Agric Food Chem 62:3011–3033

    Article  CAS  PubMed  Google Scholar 

  • Kamarudin MNA, Sarker MMR, Kadir HA, Ming LC (2017) Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Clinacanthus nutans (Burm. f.) Lindau: a comprehensive review. J Ethnopharmacol 206:245–266

    Article  CAS  PubMed  Google Scholar 

  • Kawaii S, Tomono Y, Katase E, Ogawa K, Yano M (1999) Quantitation of flavonoid constituents in citrus fruits. J Agric Food Chem 47:3565–3571

    Article  CAS  PubMed  Google Scholar 

  • Khanam Z, Ching CH, Zakaria NHBM, Sam KH, Bhat IUH (2014) Phytochemical analyses and DNA cleavage activity of Citrus maxima fruit. In: International conference on chemistry and environmental sciences research (ICCESR), pp 17–18

    Google Scholar 

  • Kingston PF (2002) Long-term environmental impact of oil spills. Spill Sci Technol Bull 7:53–61

    Article  CAS  Google Scholar 

  • Kittler J, Krüger H, Ulrich D, Zeiger B, Schütze W, Böttcher C et al (2018) Content and composition of essential oil and content of rosmarinic acid in lemon balm and balm genotypes (Melissa officinalis). Genet Resour Crop Evol 65:1517–1527

    Article  CAS  Google Scholar 

  • Kumar R, Vijay S, Khan N (2013) Comparative nutritional analysis and antioxidant activity of fruit juices of some citrus spp. Octa J Biosci 1:44–53

    Google Scholar 

  • Kumar D, Ladaniya MS, Gurjar M (2019) Underutilized Citrus sp. Pomelo (Citrus grandis) and Kachai lemon (Citrus jambhiri) exhale in phytochemicals and antioxidant potential. J Food Sci Technol 56:217–223

    Article  CAS  PubMed  Google Scholar 

  • Kundu Sen S, Saha P, Bhattacharya S, Bala A, Mazumder UK, Gupta M, Haldar PK (2010) Evaluation of in vitro antioxidant activity of Citrus limetta and Citrus maxima on reactive oxygen and nitrogen species. Pharmacol Online 3:850–857

    Google Scholar 

  • Kundu Sen S, Gupta M, Mazumder UK, Haldar PK, Saha P, Bala A (2011a) Antitumor activity of Citrus maxima (Burm.) Merr. leaves in Ehrlich’s Ascites Carcinoma cell-treated mice. Int Sch Res 2011:138737

    Google Scholar 

  • Kundu Sen S, Gupta M, Mazumder UK, Haldar PK, Saha P, Bhattacharya S et al (2011b) Antihyperglycemic effect and antioxidant property of Citrus maxima leaf in streptozotocin-induced diabetic rats. Diabetol Croat 40:1–6

    Google Scholar 

  • Kundu Sen S, Gupta M, Mazumder UK, Haldar P, Panda S, Bhattacharya S (2011c) Exploration of anti-inflammatory potential of Citrus limetta Risso and Citrus maxima (J. Burm.) Merr. Pharmacol Online 7:702–709

    Google Scholar 

  • Kuo SM (1996) Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett 110:41–48

    Article  CAS  PubMed  Google Scholar 

  • Kuo PC, Liao YR, Hung HY, Chuang CW, Hwang TL, Huang SC, Wu TS (2017) Anti-inflammatory and neuroprotective constituents from the peels of Citrus grandis. Molecules 22:1–11

    Google Scholar 

  • Lan-Phi NT, Vy TT (2015) Chemical composition, antioxidant and antibacterial activities of peels’ essential oils of different pomelo varieties in the south of Vietnam. Int Food Res J 22:2426

    CAS  Google Scholar 

  • Lellis B, Fávaro-Polonio CZ, Pamphile JA, Polonio JC (2019) Effects of textile dyes on health and the environment and bioremediation potential of living organisms. Biotechnol Res Innov 3:275–290

    Article  Google Scholar 

  • Li F, Li S, Li HB, Deng GF, Ling WH, Wu S et al (2013) Antiproliferative activity of peels, pulps and seeds of 61 fruits. J Funct Foods 5(3):1298–1309

    Article  Google Scholar 

  • Li PL, Liu MH, Hu JH, Su WW (2014) Systematic chemical profiling of Citrus grandis ‘Tomentosa’ by ultra-fast liquid chromatography/diode-array detector/quadrupole time-of-flight tandem mass spectrometry. J Pharm Biomed Anal 90:167–179

    Article  CAS  PubMed  Google Scholar 

  • Li H, Sun Z, Zhang L, Tian Y, Cui G, Yan S (2016) A cost-effective porous carbon derived from pomelo peel for the removal of methyl orange from aqueous solution. Colloids Surf A Physicochem Eng Asp 489:191–199

    Article  CAS  Google Scholar 

  • Li G, Cheng Y, Zhang T, Li Y, Han L, Liang G (2021) Characterization of oxygenated heterocyclic compounds and in vitro antioxidant activity of pomelo essential oil. Drug Des Devel Ther 15:937

    Article  PubMed  PubMed Central  Google Scholar 

  • Lin SP, Chao PDL, Tsai SY, Wang MJ, Hou YC (2011) Citrus grandis peel increases the bioavailability of cyclosporine and tacrolimus, two important immunosuppressants, in rats. J Med Food 14:1463–1468

    Article  CAS  PubMed  Google Scholar 

  • Lin Z, Li J, Fang S, Chen T, Chen J (2012) Analysis of volatile aroma components in pomelo peel tea by headspace-gas chromatography-mass spectrometry. Food Sci 33:256–259

    CAS  Google Scholar 

  • Ling W, Dai T, Zhang J, Liang Y, Yin W, Zhong B, Zhang J (2021) Evaluation of pomelo seed extracts as natural antioxidant, antibacterial, herbicidal agents, and their functional components. Chem Biodivers 18:e2100679

    Article  CAS  PubMed  Google Scholar 

  • Liu Y, Heying E, Tanumihardjo SA (2012) History, global distribution, and nutritional importance of citrus fruits. Compr Rev Food Sci Food Saf 11:530–545

    Article  CAS  Google Scholar 

  • Liu W, Ye Q, Jin X, Han F, Huang X, Cai S, Yang L (2016) A spontaneous bud mutant that causes lycopene and β-carotene accumulation in the juice sacs of the parental Guanxi pummelo fruits (Citrus grandis (L.) Osbeck). Sci Hortic 198:379–384

    Article  CAS  Google Scholar 

  • Liu Y, Ren C, Cao Y, Wang Y, Duan W, Xie L et al (2017a) Characterization and purification of bergamottin from Citrus grandis (L.) Osbeck cv. Yongjiazaoxiangyou and its antiproliferative activity and effect on glucose consumption in HepG2 cells. Molecules 22:1227

    Article  PubMed  PubMed Central  Google Scholar 

  • Liu Z, Zu Y, Yang L (2017b) A process to preserve valuable compounds and acquire essential oils from pomelo flavedo using a microwave irradiation treatment. Food Chem 224:172–180

    Article  CAS  PubMed  Google Scholar 

  • Liu Y, Liu A, Ibrahim SA, Yang H, Huang W (2018) Isolation and characterization ofmicrocrystalline cellulose from pomelo peel. Int J Biol Macromol 111:717–721

    Google Scholar 

  • Lu Y, Zhang C, Bucheli P, Wei D (2006) Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China. Plant Foods Hum Nutr 61:55–63

    Article  Google Scholar 

  • Lu XK, Lin QH, Lu XM, Zhang SM, Li CS, Ye XF (2012) Comparison of carotenoid compositions and contents n different sweet pomelos. Fujianj Agric Sci 27:723–727

    CAS  Google Scholar 

  • Lü Z, Zhang Z, Wu H, Zhou Z, Yu J (2016) Phenolic composition and antioxidant capacities of Chinese local pummelo cultivars’ peel. Hortic Plant J 2:133–140

    Article  Google Scholar 

  • Lukitaningsih E, Rumiyati R (2021) GC-MS analysis of bioactive compounds in ethanol and ethyl acetate fraction of grapefruit (Citrus maxima L.) rind. Borneo J Pharm 4:29–35

    Article  Google Scholar 

  • Mahato N, Sharma K, Koteswararao R, Sinha M, Baral E, Cho MH (2019) Citrus essential oils: extraction, authentication and application in food preservation. Crit Rev Food Sci Nutr 59:611–625

    Article  CAS  PubMed  Google Scholar 

  • Mäkynen K, Jitsaardkul S, Tachasamran P, Sakai N, Puranachoti S, Nirojsinlapachai N et al (2013) Cultivar variations in antioxidant and antihyperlipidemic properties of pomelo pulp (Citrus grandis (L.) Osbeck) in Thailand. Food Chem 139:735–743

    Article  PubMed  Google Scholar 

  • Mansour R (2018) Determination of nutritional composition in citrus fruits (C. aurantium) during maturity. Nutr Food Sci. https://doi.org/10.1108/NFS-05-2018-0141

  • Matheyambath AC (2016) Citrus fruits. Encyclopedia of food and health. Elsevier Press, Oxford, pp 136–140

    Book  Google Scholar 

  • McIntosh CA, Mansell RL (1997) Three-dimensional distribution of limonin, limonoate A-ring monolactone, and naringin in the fruit tissues of three varieties of Citrus paradisi. J Agric Food Chem 45:2876–2883

    Article  CAS  Google Scholar 

  • Medeiros KAA, Dos Santos JR, Melo TCDS, de Souza MF, Santos LDG, de Gois AM et al (2018) Depressant effect of geraniol on the central nervous system of rats: behavior and ECoG power spectra. Biom J 41:298–305

    Google Scholar 

  • Mesbahi G, Jamalian J, Farahnaky A (2005) A comparative study on functional properties of beet and citrus pectins in food systems. Food Hydrocoll 19:731–738

    Article  CAS  Google Scholar 

  • Methacanon P, Krongsin J, Gamonpilas C (2014) Pomelo (Citrus maxima) pectin: effects of extraction parameters and its properties. Food Hydrocoll 35:383–391

    Article  CAS  Google Scholar 

  • Miller JA, Thompson PA, Hakim IA, Lopez AM, Thomson CA, Chew W et al (2012) Safety and feasibility of topical application of limonene as a massage oil to the breast. J Cancer Ther 3:1–12

    Article  Google Scholar 

  • Mokbel MS, Hashinaga F (2006) Evaluation of the antioxidant activity of extracts from buntan (Citrus grandis Osbeck) fruit tissues. Food Chem 94:529–534

    Article  CAS  Google Scholar 

  • Mokbel MS, Suganuma T (2006) Antioxidant and antimicrobial activities of the methanol extracts from pummelo (Citrus grandis Osbeck) fruit albedo tissues. Eur Food Res Technol 224:39–47

    Article  CAS  Google Scholar 

  • Nair A, Kurup R Sr, Nair AS, Baby S (2018) Citrus peels prevent cancer. Phytomedicine 50:231–237

    Article  PubMed  Google Scholar 

  • Noreen A, Akram J, Rasul I, Mansha A, Yaqoob N, Iqbal R et al (2017) Pectins functionalized biomaterials; a new viable approach for biomedical applications: a review. Int J Biol Macromol 101:254–272

    Article  CAS  PubMed  Google Scholar 

  • Nowicki P, Kazmierczak-Razna J, Pietrzak R (2016) Physicochemical and adsorption properties of carbonaceous sorbents prepared by activation of tropical fruit skins with potassium carbonate. Mater Des 90:579–585

    Article  CAS  Google Scholar 

  • Oboh G, Bello FO, Ademosun AO (2014) Hypocholesterolemic properties of grapefruit (Citrus paradisii) and shaddock (Citrus maxima) juices and inhibition of angiotensin-1-converting enzyme activity. J Food Drug Anal 22:477–484

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Oyedepot A, Babarinde SO (2013) Effects of shaddock (Citrus maxima) fruit juice on glucose tolerance and lipid profile in type-II diabetic rats. Chem Sci Trans 2:19–24

    Article  Google Scholar 

  • Palazzolo E, Laudicina VA, Germanà MA (2013) Current and potential use of citrus essential oils. Curr Org Chem 17:3042–3049

    Article  CAS  Google Scholar 

  • Pallavi M, Ramesh C, Krishna V, Sameera P, Swamy L (2017) Quantitative phytochemical analysis and antioxiant activities of some citrus fruits of South India. Asian J Pharm Clin Res 10:199–205

    Google Scholar 

  • Pandey BP, Thapa R, Upreti A (2019) Total phenolic content, flavonoids content, antioxidant and antimicrobial activities of the leaves, peels, and fruits of locally available citrus plants collected from Kavre District of Nepal. Int J Pharmacogn Chin Med 3(3):1–6

    Article  Google Scholar 

  • Pichaiyongvongdee S, Rattanapun B, Haruenkit R (2014) Total polyphenol content and antioxidant properties in different tissues of seven pomelo (Citrus grandis (L.) osbeck) cultivars. Agric Nat Resour 48:989–996

    Google Scholar 

  • Poulose SM, Harris ED, Patil BS (2005) Citrus limonoids induce apoptosis in human neuroblastoma cells and have radical scavenging activity. J Nutr 135:870–877

    Article  CAS  PubMed  Google Scholar 

  • Puglisi I, De Patrizio A, Schena L, Jung T, Evoli M, Pane A et al (2017) Two previously unknown Phytophthora species associated with brown rot of Pomelo (Citrus grandis) fruits in Vietnam. PLoS One 12:e0172085

    Article  PubMed  PubMed Central  Google Scholar 

  • Purseglove JW (1974) Rubiaceae. In: Purseglove JW (ed) Tropical crops dicotyledons. Longman Group Limited, London, pp 451–492

    Google Scholar 

  • Reshmi SK, Manonmani HK, Manjunatha JR, Shashirekha MN (2018) Identification of bioactive compound from Citrus maxima fruit against carbohydrate-hydrolysing enzymes. Curr Sci 114:2099–2105

    Article  CAS  Google Scholar 

  • Reshmi SK, Sudha ML, Shashirekha MN (2020) Noodles fortified with Citrus maxima (pomelo) fruit segments suiting the diabetic population. Bioact Carbohydr Diet Fibre 22:100213

    Article  CAS  Google Scholar 

  • Rex JRS, Muthukumar NMSA, Selvakumar PM (2018) Phytochemicals as a potential source for anti-microbial, anti-oxidant and wound healing – a review. MOJ Biorg Org Chem 2:61–70

    Google Scholar 

  • Roy MC, Alam M, Saeid A, Das BC, Mia MB, Rahman MA et al (2018) Extraction and characterization of pectin from pomelo peel and its impact on nutritional properties of carrot jam during storage. J Food Process Preserv 42:e13411

    Article  Google Scholar 

  • Sahlan M, Damayanti V, Tristantini D, Hermansyah H, Wijanarko A, Olivia Y (2018) Antimicrobial activities of pomelo (Citrus maxima) seed and pulp ethanolic extract. In: AIP conference proceedings, vol 1933. AIP Publishing LLC, p 030002

    Google Scholar 

  • Saiprasad G, Chitra P, Manikandan R, Sudhandiran G (2013) Hesperidin alleviates oxidative stress and downregulates the expressions of proliferative and inflammatory markers in azoxymethane-induced experimental colon carcinogenesis in mice. Inflamm Res 62:425–440

    Article  CAS  PubMed  Google Scholar 

  • Samaniego I, Brito B, Viera W, Cabrera A, Llerena W, Kannangara T et al (2020) Influence of the maturity stage on the phytochemical composition and the antioxidant activity of four Andean blackberry cultivars (Rubus glaucus Benth) from Ecuador. Plan Theory 9:1027

    CAS  Google Scholar 

  • Sarkic A, Stappen I (2018) Essential oils and their single compounds in cosmetics – a critical review. Cosmetics 5:11

    Article  Google Scholar 

  • Sawant TP, Panhekar D (2017) A brief review on recent advances of Citrus maxima (chakota). Int J Rec Sci Res 8:19400–19416

    Google Scholar 

  • Sen S, Ingale SL, Kim JS, Kim KH, Kim YW, Khong C, Chae BJ (2011) Effect of supplementationof Bacillus subtilis LS 1-2 grown on citrus-juice waste and corn-soybean meal substrate ongrowth performance, nutrient retention, caecal microbiology and small intestinal morphology ofbroilers. Asian-Australas J Anim Sci 24:1120–1127

    Google Scholar 

  • Senguttuvan J, Paulsamy S, Karthika K (2014) Phytochemical analysis and evaluation of leaf and root parts of the medicinal herb, Hypochaeris radicata L. for in vitro antioxidant activities. Asian Pac J Trop Biomed 4:S359–S367

    Article  PubMed  PubMed Central  Google Scholar 

  • Shah NNAK, Supian NAM, Hussein NA (2019) Disinfectant of pummelo (Citrus grandis L. Osbeck) fruit juice using gaseous ozone. J Food Sci Technol 56:262–272

    Article  CAS  PubMed  Google Scholar 

  • Shao SY, Xu WJ, Tao J, Zhang JH, Zhou XR, Yuan G et al (2017) Glycemic index, glycemic load, and glycemic response to pomelo in patients with type 2 diabetes. Curr Med Sci 37:711–718

    Article  CAS  Google Scholar 

  • Sharma P, Kumar V, Guleria P (2019) Naringin: biosynthesis and pharmaceutical applications. Indian J Pharm Sci 81:988–999

    Article  CAS  Google Scholar 

  • Shinde M, Sonawane SK, Patil S (2019) Fruit peel utilization in food packaging. Indian Food Ind Mag 1:19–24

    Google Scholar 

  • Shivananda A, Rao DM, Jayaveera KN (2013) Analgesic and anti-inflammatory activities of Citrus maxima (J. Burm) Merr in animal models. Res J Pharm, Biol Chem Sci 4:1800–1810

    Google Scholar 

  • Sidana J, Saini V, Dahiya S, Nain P, Bala S (2013) A review on citrus – “the boon of nature”. Int J Pharm Sci Rev Res 18:20–27

    Google Scholar 

  • Singh A (2016) Evaluation of antimicrobial potential and phytochemical assessment of Citrus maxima Burm. seeds extracts against respiratory tract pathogens. New Y Sci J 9:4–10

    Google Scholar 

  • Singh A, Navneet (2016) Evaluation of antimicrobial potential and phytochemical assessment of Citrus maxima Burm. seeds extracts against respiratory tract pathogens. New Y Sci J 9:4–10

    Google Scholar 

  • Singh A, Navneet (2017) Citrus maxima (Burm.) Merr. A traditional medicine: its antimicrobial potential and pharmacological update for commercial exploitation in herbal drugs – a review. Int J ChemTech Res 10:642–651

    CAS  Google Scholar 

  • Sinha D, Satapathy T, Jain P, Chandel JP, Sahu D, Sahu B et al (2019) In vitro antidiabetic effect of neohesperidin. J Drug Deliv Ther 9:102–109

    Article  Google Scholar 

  • Slavin J (2013) Fiber and prebiotics: mechanisms and health benefits. Nutrients 5:1417–1435

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Stanisic D, Costa AF, Fávaro WJ, Tasic L, Seabra AB (2018) Anticancer activities of hesperidin and hesperetinin vivo and their potentiality against bladder cancer. J Nanomed Nanotechnol 9:1–6

    Article  Google Scholar 

  • Straka I, Belous OG (2015) Chemical composition of grapefruit fruitage (Citrus paradise Macf.) in terms of its nutritional value. Субтропическоедекоративноесадоводство, pp 153–160

    Google Scholar 

  • Sudto K, Pornpakakul S, Wanichwecharungruang S (2009) An efficient method for the large scale isolation of naringin from pomelo (Citrus grandis) peel. Int J Food Sci Technol 44:1737–1742

    Article  CAS  Google Scholar 

  • Sun H, Ni H, Yang Y, Chen F, Cai H, Xiao A (2014) Sensory evaluation and gas chromatography–mass spectrometry (GC-MS) analysis of the volatile extracts of pummelo (Citrus maxima) peel. Flavour Frag J 29:305–312

    Article  CAS  Google Scholar 

  • Tabeshpour J, Hosseinzadeh H, Hashemzaei M, Karimi G (2020) A review of the hepatoprotective effects of hesperidin, a flavanon glycoside in citrus fruits, against natural and chemical toxicities. DARU J Pharm Sci 28:305–317

    Article  CAS  Google Scholar 

  • Tao N, Gao Y, Liu Y, Ge F (2010) Carotenoids from the peel of Shatian pummelo (Citrus grandis Osbeck) and its antimicrobial activity. Am-Eurasian J Agric Environ Sci 7:110–115

    CAS  Google Scholar 

  • Thavanapong N, Wetwitayaklung P, Charoenteeraboon J (2010) Comparison of essential oils compositions of Citrus maxima Merr. peel obtained by cold press and vacuum stream distillation methods and of its peel and flower extract obtained by supercritical carbon dioxide extraction method and their antimicrobial activity. J Essent Oil Res 22:71–77

    Article  CAS  Google Scholar 

  • Tocmo R, Pena-Fronteras J, Calumba KF, Mendoza M, Johnson JJ (2020) Valorization of pomelo (Citrus grandis Osbeck) peel: a review of current utilization, phytochemistry, bioactivities, and mechanisms of action. Compr Rev Food Sci Food Saf 19:1969–2012

    Article  CAS  PubMed  Google Scholar 

  • Tsai HL, Chang SK, Chang SJ (2007) Antioxidant content and free radical scavenging ability of fresh red pummelo (Citrus grandis (L.) Osbeck) juice and freeze-dried products. J Agric Food Chem 55:2867–2872

    Article  CAS  PubMed  Google Scholar 

  • Tsai ML, Lin CD, Khoo KA, Wang MY, Kuan TK, Lin WC et al (2017) Composition and bioactivity of essential oil from Citrus grandis (L.) Osbeck ‘Mato Peiyu’ leaf. Molecules 22:2154

    Article  PubMed  PubMed Central  Google Scholar 

  • Tuan NT, Huong BTC, Danh LT (2019) One step extraction of essential oils and pectin from pomelo (Citrus grandis) peels. Chem Eng Process 142:107550

    Article  Google Scholar 

  • Turner T, Burri BJ (2013) Potential nutritional benefits of current citrus consumption. Agriculture 3:170–187

    Article  Google Scholar 

  • Vadivukarasi G, Jenitha XA (2015) In vitro studies on phytochemical analysis and antioxidant activity of Citrus maxima. Int J Res Pharmacol Pharmacother 4:245–251

    CAS  Google Scholar 

  • Van Hung P, Yen Nhi NH, Ting LY, Lan Phi NT (2020) Chemical composition and biological activities of extracts from pomelo peel by-products under enzyme and ultrasound-assisted extractions. J Chemother 2020:1–7

    Google Scholar 

  • Vijayalakshmi P, Radha R (2016a) In vitro anti-alzheimer and anti oxidant activity of the peels of Citrus maxima fruits. Res J Pharmacol Pharmacodyn 8:17

    Article  Google Scholar 

  • Vijayalakshmi P, Radha R (2016b) Pharmacognostical and phytochemical screening of the peels of Citrus maxima. Microscopy 14:16

    Google Scholar 

  • Wadhwa R, Paudel KR, Chin LH, Hon CM, Madheswaran T, Gupta G et al (2021) Anti-inflammatory and anticancer activities of Naringenin-loaded liquid crystalline nanoparticles in vitro. J Food Biochem 45:e13572

    Article  CAS  PubMed  Google Scholar 

  • Wandee Y, Uttapap D, Puncha-arnon S, Puttanlek C, Rungsardthong V, Wetprasit N (2014) Enrichment of rice noodles with fibre-rich fractions derived from cassava pulp and pomelo peel. Int J Food Sci Technol 49:2348–2355

    Article  CAS  Google Scholar 

  • Wang YC, Chuang YC, Hsu HW (2008) The flavonoid, carotenoid and pectin content in peels of citrus cultivated in Taiwan. Food Chem 106:277–284

    Article  CAS  Google Scholar 

  • Wintergerst ES, Maggini S, Hornig DH (2006) Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab 50:85–94

    Article  CAS  PubMed  Google Scholar 

  • Wu CH, Huang SM, Lin JA, Yen GC (2011) Inhibition of advanced glycation endproduct formation by foodstuffs. Food Funct 2:224–234

    Article  CAS  PubMed  Google Scholar 

  • Wu F, Jin Y, Xu X, Yang N (2017) Electrofluidic pretreatment for enhancing essential oil extraction from citrus fruit peel waste. J Clean Prod 159:85–94

    Article  CAS  Google Scholar 

  • Wu Y, Huang C, Gong J, Huang J, Pan T (2021) Analysis of carotenoid components in ‘Minihongyou’ (Citrus maxima (Burm.) Merr.) fruit by HPLC. Chinese J Trop Crops 42:546

    Google Scholar 

  • Xi W, Fang B, Zhao Q, Jiao B, Zhou Z (2014) Flavonoid composition and antioxidant activities of Chinese local pummelo (Citrus grandis Osbeck.) varieties. Food Chem 161:230–238

    Article  CAS  PubMed  Google Scholar 

  • Xiao L, Ye F, Zhou Y, Zhao G (2021) Utilization of pomelo peels to manufacture value-added products: a review. Food Chem 351:129247

    Article  CAS  PubMed  Google Scholar 

  • Xiong H, Wang J, Ran Q, Lou G, Peng C, Gan Q et al (2019) Hesperidin: a therapeutic agent for obesity. Drug Des Devel Ther 13:3855

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Xu CJ, Fraser PD, Wang WJ, Bramley PM (2006) Differences in the carotenoid content of ordinary citrus and lycopene-accumulating mutants. J Agric Food Chem 54:5474–5481

    Article  CAS  PubMed  Google Scholar 

  • Xu YR, Zhang KF, Xie QJ, Lin JX, Huan KX, Liao Y (2015) Chemical constituents from young fruits of Citrus maxima cv. Shatian. Zhong yaocai = Zhongyaocai = J Chinese Med Mat 38:1879–1881

    CAS  Google Scholar 

  • Yan F, Shi M, He Z, Wu L, Xu X, He M, Chen J, Deng X, Cheng Y, Xu J (2018) Largely different carotenogenesis in two pummelo fruits with different flesh colors. PLoS One 13:e0200320

    Article  PubMed  PubMed Central  Google Scholar 

  • Yaseen DA, Scholz M (2019) Textile dye wastewater characteristics and constituents of synthetic effluents: a critical review. Int J Environ Sci Technol 16:1193–1226

    Article  CAS  Google Scholar 

  • Yathiender S (2017) A comparative study of antimicrobial activity of Citrus maxima and Citrus Aurantium plant extracts. Int J Recent Sci Res 8:18507–18509

    Google Scholar 

  • Yu EA, Kim GS, Lee JE, Park S, Yi S, Lee SJ et al (2015) Flavonoid profiles of immature and mature fruit tissues of Citrus grandis Osbeck (Dangyuja) and overall contribution to the antioxidant effect. Biomed Chromatogr 29:590–594

    Article  CAS  PubMed  Google Scholar 

  • Zain NM, Yusop SM, Ahmad I (2014) Preparation and characterization of cellulose and nanocellulose from pomelo (Citrus grandis) albedo. J Nutr Food Sci 5:334

    Google Scholar 

  • Zhang M, Li L, Wu Z, Wang Y, Zang Y, Liu G (2017) Volatile composition in two pummelo cultivars (Citrus grandis L. Osbeck) from different cultivation regions in China. Molecules 22:716

    Article  PubMed  PubMed Central  Google Scholar 

  • Zhao YL, Yang XW, Wu BF, Shang JH, Liu YP, Zhi-Dai Luo XD (2019) Anti-inflammatory effect of pomelo peel and its bioactive coumarins. J Agric Food Chem 67:8810–8818

    Article  CAS  PubMed  Google Scholar 

  • Zhu J, Liu Q, Li Z, Liu J, Zhang H, Li R et al (2017) Recovery of uranium (VI) from aqueous solutions using a modified honeycomb-like porous carbon material. Dalton Trans 46:420–429

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Kushwaha, R., Singh, V., Kushwaha, P.P., Kaur, D. (2023). Pomelo. In: Singh Purewal, S., Punia Bangar, S., Kaur, P. (eds) Recent Advances in Citrus Fruits. Springer, Cham. https://doi.org/10.1007/978-3-031-37534-7_5

Download citation

Publish with us

Policies and ethics