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Preoperative Molecular Testing for Indeterminate Thyroid Nodules

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Controversies in Thyroid Nodules and Differentiated Thyroid Cancer

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Abstract

Molecular testing has emerged as a valuable tool in the preoperative evaluation of cytologically indeterminate thyroid nodules. The addition of molecular testing to Bethesda III and IV thyroid FNAs has resulted in an overall decrease in diagnostic lobectomies/thyroidectomies. However, molecular testing is not indicated in all patients. This chapter highlights the clinical considerations when determining the appropriate usage of molecular testing in cytologically indeterminate thyroid nodules and currently available tests.

C Davis, N Addasi are co-first authors

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Authors and Affiliations

  1. Department of Internal Medicine, Division of Diabetes, Endocrinology, and Metabolism, University of Nebraska Medical Center, 984120 Nebraska Medical Center, Omaha, NE, USA

    Clifton Davis, Noor Addasi & Whitney S. Goldner

  2. Cotton O’Neil Diabetes and Endocrinology, Stormont Vail Health, Topeka, KS, USA

    Noor Addasi

Authors
  1. Clifton Davis
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  2. Noor Addasi
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  3. Whitney S. Goldner
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Corresponding author

Correspondence to Whitney S. Goldner .

Editor information

Editors and Affiliations

  1. Department of Surgery, University of California, San Francisco, San Francisco, CA, USA

    Sanziana A. Roman

  2. Department of Surgery, University of California, San Francisco, San Francisco, CA, USA

    Wen T. Shen

  3. Department of Surgery, University of California, San Francisco, San Francisco, CA, USA

    Julie Ann Sosa

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Davis, C., Addasi, N., Goldner, W.S. (2023). Preoperative Molecular Testing for Indeterminate Thyroid Nodules. In: Roman, S.A., Shen, W.T., Sosa, J.A. (eds) Controversies in Thyroid Nodules and Differentiated Thyroid Cancer. Springer, Cham. https://doi.org/10.1007/978-3-031-37135-6_3

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  • DOI: https://doi.org/10.1007/978-3-031-37135-6_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-37134-9

  • Online ISBN: 978-3-031-37135-6

  • eBook Packages: MedicineMedicine (R0)

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