Abstract
Wound healing is a complex mechanism that involves different types of cells to restore damaged skin layers. Therefore, different types of medical bandages are used. Keratin and Matricaria chamomilla extract based electrospun medical dressings may improve wound healing process due to promotion of different types of cells that take act in skin regeneration process. Biosynthesized silver nanoparticles can upgrade these bandages due to the strong antibacterial activity. However, the addition of AgNPs to keratin composition may affect electrospinability. The aim of this research is to investigate the possibility to obtain electrospun keratin mats containing biosynthesized silver nanoparticles for medical applications. Therefore, herbal extract and AgNPs were investigated, their influence on keratin compositions viscosity, electroconductivity and electrospinability were evaluated. It was determined that biosyntesized AgNPs improve phenolic and antioxidant activity, however, they lessen keratin composition viscosity, electroconductivity, and electrospinability. Thus, a more viscous keratin solution for mats electrospinning should be used.
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Acknowledgements
This work was supported by the Research Council of Lithuania [grant number P-SV-22-73] and by the European Regional Development Fund [grant number 01.2.2-MITA-K-702-10-0004].
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Andziukevičiūtė-Jankūnienė, A. et al. (2023). Investigation of Electrospun Keratin Mats Containing Biosynthesized Silver Nanoparticles. In: Dekhtyar, Y., Saknite, I. (eds) 19th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics. NBC 2023. IFMBE Proceedings, vol 89. Springer, Cham. https://doi.org/10.1007/978-3-031-37132-5_9
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DOI: https://doi.org/10.1007/978-3-031-37132-5_9
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