Skip to main content
SpringerLink
Log in

Miscellaneous Rare Malignancies: Intra-abdominal Lymphomas

  • Chapter
  • First Online:
Oncologic Surgical Emergencies

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

  • 203 Accesses

Abstract

Gastrointestinal lymphomas are a heterogeneous group of malignant diseases originating from the lymphoid tissue of the gastrointestinal system. Most lymphomas of the abdomen are the nodal form of disease, involving lymph nodes only, but only about one-fourth of gastrointestinal lymphomas are extranodal, that is, involving the gastrointestinal tube. Gastric lymphomas are the most common lymphomas of the gastrointestinal system. They account for about 3–5% of all gastric tumors. Some forms of gastric lymphomas are related to chronic H. pylori infection. Gastrointestinal lymphomas, either arising in the stomach, small bowel, or colon, present usually with nonspecific symptoms of abdominal pain, weight loss, and nausea/vomiting. Rarely they can present with an acute abdomen due to perforation or bleeding, or with obstructive symptoms. In an emergency, CT scan is the diagnostic modality of choice, but if the patient is stable enough, an endoscopy may help with the diagnosis. Emergency management is usually conservative, so that the patient can start chemotherapy as soon as possible, but surgery can have a role in complicated gastrointestinal lymphomas, in particular of the small bowel. In fact, in emergency, often it is difficult to have a precise diagnosis before the emergency laparotomy and patients presenting with a perforated mass of the bowel undergo laparotomy and resection well before a diagnosis of lymphoma is confirmed. In these cases, surgery has a double value of diagnosis and treatment. Although surgery has a role in the management of complications, long survival can be obtained only with chemotherapy and in the case of marginal zone lymphomas (MALT) with the eradication of H. pylori.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bonadonna G, Robustelli Della Cuna G, Valagusa P. Medicina Oncologica. 8th ed. Elsevier Masson: Milano; 2007.

    Google Scholar 

  2. Bowzyk Al-Naeeb A, Ajithkumar T, Behan S, Hodson DJ. Non-Hodgkin lymphoma. BMJ. 2018;362:k3204.

    Article  PubMed  Google Scholar 

  3. de Leval L, Jaffe ES. Lymphoma classification. Cancer J. 2020;26(3):176–85.

    Article  PubMed  Google Scholar 

  4. Swerdlow SH, Campo E, Harris NL, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon, France: International Agency for Research on Cancer; 2017.

    Google Scholar 

  5. Freeman C, Berg JW, Cutler SJ. Occurrence and prognosis of extranodal lymphomas. Cancer. 1972;29:252–60.

    Article  CAS  PubMed  Google Scholar 

  6. Ghimire P, Wu GY, Zhu L. Primary gastrointestinal lymphoma. World J Gastroenterol. 2011;17(6):697–707.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Ghai S, Pattison J, Ghai S, O’Malley ME, Khalili K, Stephens M. Primary gastrointestinal lymphoma: Spectrum of imaging findings with pathologic correlation. Vol. 27, Radiographics. 2007. p. 1371–1388.

    Google Scholar 

  8. Gurney KA, Cartwright RA, Gilman EA. Descriptive epidemiology of gastrointestinal non-Hodgkin’s lymphoma in a population-based registry. Br J Cancer. 1999;79(11–12):1929–34.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Lo Re G, Federica V, Midiri F, et al. Radiological features of gastrointestinal lymphoma. Gastroenterol Res Pract. 2016;2016:2498143.

    PubMed  Google Scholar 

  10. Dawson IM, Cornes JS, Morson BC. Primary malignant lymphoid tumours of the intestinal tract. Report of 37 cases with a study of factors influencing prognosis. Br J Surg. 1961;49:80–9.

    Article  CAS  PubMed  Google Scholar 

  11. Bautista-Quach MA, Ake CD, Chen M, Wang J. Gastrointestinal lymphomas: morphology, immunophenotype and molecular features. J Gastrointest Oncol. 2012;3:209–25.

    PubMed  PubMed Central  Google Scholar 

  12. Pizzi M, Sabattini E, Parente P, Bellan A, Doglioni C, Lazzi S. Gastrointestinal lymphoproliferative lesions: a practical diagnostic approach. Pathologica. 2020;112(3):227–47.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Olszewska-Szopa M, Wróbel T. Gastrointestinal non-Hodgkin lymphomas. Adv Clin Exp Med. 2019;28(8):1119–24.

    Article  PubMed  Google Scholar 

  14. Rizvi MA, Evens AM, Tallman MS, Nelson BP, Rosen ST. T-cell non-Hodgkin lymphoma. Blood. 2006;107:1255–64.

    Article  CAS  PubMed  Google Scholar 

  15. Elenitoba-Johnson KSJ, Lim MS. New insights into lymphoma pathogenesis. Annu Rev Pathol. 2018;13:193–217.

    Article  CAS  PubMed  Google Scholar 

  16. Psyrri A, Papageorgiou S, Economopoulos T. Primary extranodal lymphomas of stomach: clinical presentation, diagnostic pitfalls and management. Ann Oncol. 2008;19:1992–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Ferreri AJ, Montalbán C. Primary diffuse large B-cell lymphoma of the stomach. Crit Rev Oncol Hematol. 2007;63:65–71.

    Article  PubMed  Google Scholar 

  18. Swerdlow SH, Campo E, Harris NL, et al. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). In: Swerdlow SH, Campo E, Harris NL, et al., editors. World Health Organization classification of tumours of haematopoietic and lymphoid tissues (4th edition). Lyon: IARC Press; 2008. p. 214–7.

    Google Scholar 

  19. Lecuit M, Abachin E, Martin A, et al. Immunoproliferative small intestinal disease associated with campylobacter jejuni. N Engl J Med. 2004;350:239–48.

    Article  CAS  PubMed  Google Scholar 

  20. Matasar MJ, Zelenetz AD. Overview of lymphoma diagnosis and management. Radiol Clin N Am. 2008;46(2):175–98. vii

    Article  PubMed  Google Scholar 

  21. Azab MB, Henry-Amar M, Rougier P. Prognostic factors in primary gastrointestinal non-Hodgkin’s lymphoma. A multivariate analysis, report of 106 cases, and review of the literature. Cancer. 1989;64:1208–17.

    Article  CAS  PubMed  Google Scholar 

  22. Rohatiner A, D’Amore F, Coiffier B, et al. Report on a workshop convened to discuss the pathological and staging classifications of gastrointestinal tract lymphoma. Ann Oncol. 1994;5:397–400.

    Article  CAS  PubMed  Google Scholar 

  23. May A, Nachbar L, Pohl J, et al. Endoscopic interventions in the small bowel using double balloon enteroscopy: feasibility and limitations. Am J Gastroenterol. 2007;102:527–35.

    Article  PubMed  Google Scholar 

  24. Kobayashi K, Katsumata T, Saigenji K. Clinical usefulness of single-balloon enteroscopy in the diagnosis and treatment of small-intestinal diseases. In: Niwa H, editor. New challenges in gastrointestinal endoscopy. Springer; 2008. p. 243–50.

    Chapter  Google Scholar 

  25. Flieger D, Keller J, May A, et al. Capsule endoscopy in gastrointestinal lymphomas. Endoscopy. 2000;37:1174–80.

    Article  Google Scholar 

  26. Boot H. In: Thesis, editor. Gastric MALT-lymphoma. Studies on diagnosis, pathogenesis and treatment. Amsterdam: Thesis Publishers; 1997.

    Google Scholar 

  27. Fischbach W, Dragosics B, Kolve-Goebeler M-E, et al. Primary gastric B-cell lymphoma: results of a prospective multicenter study. Gastroenterology. 2000;119:1191–202.

    Article  CAS  PubMed  Google Scholar 

  28. Boot H, de Jong D. Diagnosis, treatment decisions, and follow-up in primary gastric lymphoma. Gut. 2002;51:621–2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Fischbach W. Gastric mucosa-associated lymphoid tissue lymphoma: a challenge for endoscopy. Gastrointest Endosc. 2008;68:632–4.

    Article  PubMed  Google Scholar 

  30. Liu H, Ye H, Ruskone-Fourmestraux A, et al. T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology. 2002;122:1286–94.

    Article  CAS  PubMed  Google Scholar 

  31. Boot H. Diagnosis and staging in gastrointestinal lymphoma. Best Pract Res Clin Gastroenterol. 2010;24(1):3–12.

    Article  PubMed  Google Scholar 

  32. Boveri E, Arcaini L, Merli M, et al. Bone marrow histology in marginal zone B-cell lymphomas: correlation with clinical parameters and flow cytometry in 120 patients. Ann Oncol. 2009;20:129–36.

    Article  CAS  PubMed  Google Scholar 

  33. Raderer M, Vorbeck F, Formanek M, et al. Importance of extensive staging in patients with mucosa-associated lymphoid tissue (MALT-type)-lymphoma. Br J Cancer. 2000;83:454–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  34. Jerusalem G, Beguin Y, Fassotte MF, et al. Whole-body positron emission tomography using 18F-fluorodeoxyglucose for posttreatment evaluation in Hodgkin’s disease and non-Hodgkin lymphoma has higher diagnostic and prognostic value than classical computed tomography scan imaging. Blood. 1999;94:429–33.

    Article  CAS  PubMed  Google Scholar 

  35. Isai CR, Lu P, Blaufox MD. A meta-analysis of 18F-2-deoxy-2-fluoro-D-glucose positron emission tomography in the staging and restaging of patients with lymphoma. Cancer. 2005;104:1066–74.

    Article  Google Scholar 

  36. Raderer M, Wöhrer S, Streubel B, et al. Assessment of disease dissemination in gastric compared with extragastric mucosa-associated lymphoid tissue lymphoma using extensive staging: a single-center experience. J Clin Oncol. 2006;24:3136–41.

    Article  PubMed  Google Scholar 

  37. Juárez-Salcedo LM, Sokol L, Chavez JC, Dalia S. Primary gastric lymphoma, epidemiology, clinical diagnosis, and treatment. Cancer Control. 2018;25(1):1073274818778256.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Hussell T, Isaacson PG, Crabtree JE, Spencer J. Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue. J Pathol. 1996;178:122–7.

    Article  CAS  PubMed  Google Scholar 

  39. Ohkura Y, Lee S, Kaji D, Ota Y, Haruta S, Takeji Y, Shinohara H, Ueno M, Udagawa H. Spontaneous perforation of primary gastric malignant lymphoma: a case report and review of the literature. World J Surg Oncol. 2015;13:35. https://doi.org/10.1186/s12957-015-0458-0.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Ono K, Matsumura S, Sakamoto K, Kobayashi S, Kamano T, Iwasaki R. A case of gastric malignant lymphoma with perforation during chemotherapy. Gan To Kagaku Ryoho. 1997;24(1):105–8.

    CAS  PubMed  Google Scholar 

  41. Shiomi H, Watanabe E, Umeda T. A case report of perforated gastric malignant lymphoma. Jpn J Cancer Clin. 1997;43:25–8.

    Google Scholar 

  42. Bestari MB, Palungkun IG, Hernowo BS, Abdurachman SA, Nugraha ES. Low-stage gastric MALT lymphoma causing life-threatening upper gastrointestinal bleeding. Case Rep Gastroenterol. 2019;13(3):376–84.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Taal BG, Burgers JM. Primary non-Hodgkin’s lymphoma of the stomach: endoscopic diagnosis and the role of surgery. Scand J Gastroenterol Suppl. 1991;188:33–7.

    Article  CAS  PubMed  Google Scholar 

  44. Püspök A, Raderer M, Chott A, Dragosics B, Gangl A, Schöfl R. Endoscopic ultrasound in the follow up and response assessment of patients with primary gastric lymphoma. Gut. 2002;51:691–4.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Al-Akwaa AM, Siddiqui N, Al-Mofleh IA. Primary gastric lymphoma. World J Gastroenterol. 2004;10:5–11.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Lupescu IG, Grasu M, Goldis G, Popa G, Gheorghe C, Vasilescu C, Moicean A, Herlea V, Georgescu SA. Computer tomographic evaluation of digestive tract non-Hodgkin lymphomas. J Gastrointestin Liver Dis. 2007;16:315–9.

    PubMed  Google Scholar 

  47. Radan L, Fischer D, Bar-Shalom R, Dann EJ, Epelbaum R, Haim N, Gaitini D, Israel O. FDG avidity and PET/CT patterns in primary gastric lymphoma. Eur J Nucl Med Mol Imaging. 2008;35:1424–30.

    Article  PubMed  Google Scholar 

  48. Stathis A, Chini C, Bertoni F, Proserpio I, Capella C, Mazzucchelli L, Pedrinis E, Cavalli F, Pinotti G, Zucca E. Long-term outcome following helicobacter pylori eradication in a retrospective study of 105 patients with localized gastric marginal zone B-cell lymphoma of MALT type. Ann Oncol. 2009;20:1086–93.

    Article  CAS  PubMed  Google Scholar 

  49. Greiner A, Knörr C, Qin Y, Sebald W, et al. Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT-type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation. Am J Pathol. 1997;150(5):1583–93.

    CAS  PubMed  PubMed Central  Google Scholar 

  50. Raderer M, Wöhrer S, Kiesewetter B, et al. Antibiotic treatment as sole management of helicobacter pylori-negative gastric MALT lymphoma: a single center experience with prolonged follow-up. Ann Hematol. 2015;94(6):969–73.

    Article  CAS  PubMed  Google Scholar 

  51. Egger ME, Ikoma N, Badgwell BD. Primary gastric malignancies. In: The MD Anderson surgical oncology handbook. 6th ed. Wolters Kluwer Health Adis (ESP); 2018. p. 417–9.

    Google Scholar 

  52. Ferrucci PF, Zucca E. Primary gastric lymphoma pathogenesis and treatment: what has changed over the past 10 years? Br J Haematol. 2007;136:521–38.

    Article  CAS  PubMed  Google Scholar 

  53. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2015;47(10):a1–46.

    Article  PubMed  Google Scholar 

  54. Yoon SS, Coit DG, Portlock CS, Karpeh MS. The diminishing role of surgery in the treatment of gastric lymphoma. Ann Surg. 2004;240(1):28–37.

    Article  PubMed  PubMed Central  Google Scholar 

  55. Stabile BE, Smith BR. Cancer of the stomach: surgical management. In: Principles and practice of surgical oncology. Multidisciplinary approach to difficult problems. Lippincott Williams & Wilkins, a Wolters Kluwer Business; 2010. p. 685–7.

    Google Scholar 

  56. Speranza V, Lomanto D. Primary gastric lymphoma. In: Holzheimer RG, Mannick JA, editors. Surgical treatment: evidence-based and problem-oriented. Munich: Zuckschwerdt; 2001. https://www.ncbi.nlm.nih.gov/books/NBK6966/.

    Google Scholar 

  57. Salles G, Herbrecht R, Tilly H, et al. Aggressive primary gastrointestinal lymphomas: review of 91 patients treated with the LNH-84 regimen. A study of the groupe d’etude des lymphomes agressifs. Am J Med. 1991;90:77–84.

    Article  CAS  PubMed  Google Scholar 

  58. Ohkura Y, Lee S, Kaji D, et al. Spontaneous perforation of primary gastric malignant lymphoma: a case report and review of the literature. World J Surg Oncol. 2015;13:35.

    Article  PubMed  PubMed Central  Google Scholar 

  59. Chen G, Zhang MM, Zhu JM, Mao J, Li YM. Damage control surgery saves patient with gastric lymphoma from radical gastrectomy. J Coll Physicians Surg Pak. 2021;31(8):978–81.

    Article  PubMed  Google Scholar 

  60. Søreide K, Thorsen K, Harrison EM, et al. Perforated peptic ulcer. Lancet. 2015;386(10000):1288–98.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Cao YJ, Duan J, Liu LF, Wei X, Ren L, Zhang LN, Zhang W. Individualized treatment and palliative Care for a 90-year-old patient with primary gastric diffuse large-B cell lymphoma: 4 year follow-up and inspiration. Chin Med Sci J. 2021;36(1):72–7.

    Article  PubMed  Google Scholar 

  62. Schottenfeld D, Beebe-Dimmer JL, Vigneau FD. The epidemiology and pathogenesis of neoplasia in the small intestine. Ann Epidemiol. 2009;19:58–69.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Bilimoria KY, Bentrem DJ, Wayne JD, Ko CY, Bennett CL, Talamonti MS. Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 years. Ann Surg. 2009;249(1):63–71.

    Article  PubMed  Google Scholar 

  64. Opelz G, Daniel V, Naujokat C, Dohler B. Epidemiology of pretransplant EBV and CMV serostatus in relation to posttransplant non-Hodgkin lymphoma. Transplantation. 2009;88(8):962–7.

    Article  PubMed  Google Scholar 

  65. Howell JM, Auer-Grzesiak I, Zhang J, Andrews CN, Stewart D, Urbanski SJ. Increasing incidence rates, distribution and histological characteristics of primary gastrointestinal non-Hodgkin lymphoma in a north American population. Can J Gastroenterol. 2012;26(7):452–6.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Scott KS, James RH. Tumors of the small bowel in Morita Ys. In: Balch CM, editor. Textbook of complex general surgical oncology. McGraw-Hill Companies; 2018. p. 1637–42.

    Google Scholar 

  67. Biko DM, Anupindi SA, Hernandez A, Kersun L, Bellah R. Childhood Burkitt lymphoma: abdominal and pelvic imaging findings. AJR Am J Roentgenol. 2009;192:1304–15.

    Article  PubMed  Google Scholar 

  68. Choi SY, Kim SJ, Kim WS, et al. Aggressive B cell lymphomas of the gastrointestinal tract: clinicopathologic and genetic analysis. Virchows Arch. 2011;459:495–502.

    Article  CAS  PubMed  Google Scholar 

  69. Nguyen V, Nguyen B, Petris GD, et al. Education and imaging. Gastrointestinal: gastrointestinal involvement of mantle cell lymphoma. J Gastroenterol Hepatol. 2012;27:617.

    Article  PubMed  Google Scholar 

  70. Hirata N, Tominaga K, Ohta K, et al. A case of mucosa-associated lymphoid tissue lymphoma forming multiple lymphomatous polyposis in the small intestine. World J Gastroenterol. 2007;13:1453–7.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Al-Saleem T, Al-Mondhiry H. Immunoproliferative small intestinal disease (IPSID): a model for mature B-cell neoplasms. Blood. 2005;105:2274–80.

    Article  CAS  PubMed  Google Scholar 

  72. Garrido A, Luque A, Vázquez A, et al. Primary small bowel neoplasms as a complication of celiac disease. Gastroenterol Hepatol. 2009;32:618–21.

    Article  PubMed  Google Scholar 

  73. Ludvigsson JF, Lebwohl B, Rubio-Tapia A, et al. Does celiac disease influence survival in lymphoproliferative malignancy? Eur J Epidemiol. 2013;28(6):475–83.

    Article  CAS  PubMed  Google Scholar 

  74. Koch P, del Valle F, Berdel WE, et al. Primary gastrointestinal non-Hodgkin’s lymphoma: I. anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German multicenter study GIT NHL 01/92. J Clin Oncol. 2001;19(18):3861–73.

    Article  CAS  PubMed  Google Scholar 

  75. Ibrahim EM, Ezzat AA, El-Weshi AN, et al. Primary intestinal diffuse large B-cell non-Hodgkin’s lymphoma: clinical features, management, and prognosis of 66 patients. Ann Oncol. 2001;12(1):53–8.

    Article  CAS  PubMed  Google Scholar 

  76. Zinzani PL, Magagnoli M, Pagliani G, et al. Primary intestinal lymphoma: clinical and therapeutic features of 32 patients. Haematologica. 1997;82(3):305–8.

    CAS  PubMed  Google Scholar 

  77. Donohue JH, Schnelldorfer T. Small bowel tumors. In: Silberman H, Silberman AW, editors. Principles and practice of surgical oncology multidisciplinary approach to difficult problems. Lippincott Williams & Wilkins, a Wolters Kluwer business; 2010. p. 814–6.

    Google Scholar 

  78. Onkendi EO, Grotz TE, Murray JA, Donohue JH. Adult intussusception in the last 25 years of modern imaging: is surgery still indicated? J Gastrointest Surg. 2011;15(10):1699–705.

    Article  PubMed  Google Scholar 

  79. Beaton C, Davies M, Beynon J. The management of primary small bowel and colon lymphoma—a review. Int J Color Dis. 2012;27(5):555–63.

    Article  Google Scholar 

  80. Mitsui K, Tanaka S, Yamamoto H, et al. Role of double-balloon endoscopy in the diagnosis of small-bowel tumors; the first Japanese multicenter study. Gastrointest Endosc. 2009;70(3):498–504.

    Article  PubMed  Google Scholar 

  81. Gollub MJ. Imaging of gastrointestinal lymphoma. Radiol Clin N Am. 2008;46:287–312, ix.

    Article  PubMed  Google Scholar 

  82. Chung HH, Kim YH, Kim JH, Cha SH, Kim BH, Kim TK, Kim AR, Cho SJ. Imaging findings of mantle cell lymphoma involving gastrointestinal tract. Yonsei Med J. 2003;44:49–57.

    Article  PubMed  Google Scholar 

  83. Koniaris LG, Drugas G, Katzman PJ, Salloum R. Management of gastrointestinal lymphoma. J Am Coll Surg. 2003;197(1):127–41.

    Article  PubMed  Google Scholar 

  84. Fleming ID, Turk PS, Murphy SB, et al. Surgical implications of primary gastrointestinal lymphoma of childhood. Arch Surg. 1990;125:252–6.

    Article  CAS  PubMed  Google Scholar 

  85. Lightner AL, Shannon E, Gibbons MM, Russell MM. Primary gastrointestinal non-Hodgkin’s lymphoma of the small and large intestines: a systematic review. J Gastrointest Surg. 2016;20(4):827–39.

    Article  PubMed  Google Scholar 

  86. Lu PW, Fields AC, Yoo J, Irani J, Goldberg JE, Bleday R, Melnitchouk N. Surgical management of small bowel lymphoma. J Gastrointest Surg. 2021;25(3):757–65.

    Article  PubMed  Google Scholar 

  87. Dickson BC, Serra S, Chetty R. Primary gastrointestinal tract lymphoma: diagnosis and management of common neoplasms. Expert Rev Anticancer Ther. 2006;6:1609–28.

    Article  CAS  PubMed  Google Scholar 

  88. Yamamoto S, Nakase H, Yamashita K, et al. Gastrointestinal follicular lymphoma: review of the literature. J Gastroenterol. 2010;45:370–88.

    Article  PubMed  Google Scholar 

  89. Dionigi G, Annoni M, Rovera F, Boni L, Villa F, Castano P, Bianchi V, Dionigi R. Primary colorectal lymphomas: review of the literature. Surg Oncol. 2007;16(Suppl 1):S169–71.

    Article  PubMed  Google Scholar 

  90. Fan CW, Changchien CR, Wang JY. Primary colorectal lymphoma. Dis Colon Rectum. 2000;43:1277–82.

    Article  CAS  PubMed  Google Scholar 

  91. Foukas PG, de Leval L. Recent advances in intestinal lymphomas. Histopathology. 2015;66(1):112–36.

    Article  PubMed  Google Scholar 

  92. Niino D, Yamamoto K, Tsuruta O, et al. Regression of rectal mucosa-associated lymphoid tissue (MALT) lymphoma after antibiotic treatments. Pathol Int. 2010;60:438–44.

    Article  PubMed  Google Scholar 

  93. Hollie N, Asakrah S. MALT lymphoma of the colon: a clinicopathological review. J Clin Pathol. 2020;73(7):378–83.

    Article  PubMed  Google Scholar 

  94. Said J, Pinter-Brown L. Clinical and pathological diagnosis of peripheral T-cell lymphoma and emerging treatment options: a case-based discussion. Clin Adv Hematol Oncol. 2009;7:S1, S4–13; quiz S15.

    PubMed  Google Scholar 

  95. Abbott S, Nikolousis E, Badger I. Intestinal lymphoma—a review of the management of emergency presentations to the general surgeon. Int J Color Dis. 2015;30(2):151–7.

    Article  CAS  Google Scholar 

  96. Chou YH, Hsu HL, Lee JC, Lin BR, Liu KL. Emphysematous colitis of ascending colon with portal venous air caused by diffuse large B-cell lymphoma. J Clin Oncol. 2010;28:e496–7.

    Article  PubMed  Google Scholar 

  97. Stanojevic GZ, Nestorovic MD, Brankovic BR, Stojanovic MP, Jovanovic MM, Radojkovic MD. Primary colorectal lymphoma: an overview. World J Gastrointest Oncol. 2011;3:14–8.

    Article  PubMed  PubMed Central  Google Scholar 

  98. Vetro C, Romano A, Amico I, et al. Endoscopic features of gastro-intestinal lymphomas: from diagnosis to follow-up. World J Gastroenterol. 2014;20(36):12993–3005.

    Article  PubMed  PubMed Central  Google Scholar 

  99. Levine MS, Rubesin SE, Pantongrag-Brown L, et al. Non-Hodgkin’s lymphoma of the gastrointestinal tract: radiographic findings. Am J Roentgenol. 1997;168:167–72.

    Article  Google Scholar 

  100. Lee HJ, Han JK, Kim TK, et al. Primary colorectal lymphoma: spectrum of imaging findings with pathologic correlation. Eur Radiol. 2002;12:2242–9.

    Article  PubMed  Google Scholar 

  101. Tondini C, Giardini R, Bozzetti F, Valagussa P, Santoro A, Bertulli R, et al. Combined modality treatment for primary gastrointestinal non-Hodgkin’s lymphoma: the Milan cancer institute experience. Ann Oncol. 1993;4:831–7.

    Article  CAS  PubMed  Google Scholar 

  102. She WH, Day W, Lau PY, et al. Primary colorectal lymphoma: case series and literature review. Asian J Surg. 2011;34(3):111–4.

    Article  PubMed  Google Scholar 

  103. Pandey M, Swain J, Iyer HM, Shukla M. Primary lymphoma of the colon: report of two cases and review of literature. World J Surg Oncol. 2019;17(1):18.

    Article  PubMed  PubMed Central  Google Scholar 

  104. Zighelboim J, Larson MV. Primary colonic lymphoma. J Clin Gastroenterol. 1994;19:135–8.

    Google Scholar 

  105. Salar A, Domingo-Domenech E, Estany C, et al. Combination therapy with rituximab and intravenous or oral fludarabine in the first-line, systemic treatment of patients with extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type. Cancer. 2009;115:5210–7.

    Article  CAS  PubMed  Google Scholar 

  106. Cai S, Cannizzo F Jr, Bullard Dunn KM, Gibbs JF, CzuczmanM RA. The role of surgical intervention in non-Hodgkin’s lymphoma of the colon and rectum. Am J Surg. 2007;193:409–12; discussion 412.

    Article  PubMed  Google Scholar 

  107. Zhai L, Zhao Y, Lin L, Tian Y, Chen X, Huang H, Lin T. Non-Hodgkin’s lymphoma involving the ileocecal region: a single-institution analysis of 46 cases in a Chinese population. J Clin Gastroenterol. 2012;46(6):5091.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Digestive and Emergency Surgery, S. Maria Hospital Trust, Terni, Italy

    Alessandro Gemini & Giovanni Domenico Tebala

  2. Surgical Emergency Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

    Barza Afzal, Amr Elserafy, Lucia Lazzereschi, Antonio Matarangolo & Giovanni Domenico Tebala

Authors
  1. Alessandro Gemini
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Barza Afzal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Amr Elserafy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Lucia Lazzereschi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Antonio Matarangolo
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Giovanni Domenico Tebala
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Giovanni Domenico Tebala .

Editor information

Editors and Affiliations

  1. Emergency Surgery Dept., Parma University Hospital, Parma, Italy

    Antonio Tarasconi

  2. Oncology Dept., Parma University Hospital, Parma, Italy

    Simona Bui

  3. Digestive Surgery Dept, Ctr. Hosp. Univ. Grenoble Alpes, La Tronche, France

    Mircea Chirica

  4. Hepato-gastroenterology and Digestive oncology Dept., Grenoble-Alpes University Hospital, Grenoble, France

    Gaël Roth

  5. Department of Surgery, University of California, Irvine, Orange, CA, USA

    Jeffry Nahmias

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Gemini, A., Afzal, B., Elserafy, A., Lazzereschi, L., Matarangolo, A., Tebala, G.D. (2023). Miscellaneous Rare Malignancies: Intra-abdominal Lymphomas. In: Tarasconi, A., Bui, S., Chirica, M., Roth, G., Nahmias, J. (eds) Oncologic Surgical Emergencies. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-031-36860-8_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-36860-8_20

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-36859-2

  • Online ISBN: 978-3-031-36860-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation