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Extreme Lateral Interbody Fusion (XLIF) with Lateral Modular Plate Fixation: Preliminary Report on Clinical and Radiological Outcomes

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The Funnel: From the Skull Base to the Sacrum

Abstract

The lateral transpsoas approach (extreme lateral interbody fusion, or XLIF) allows surgeons to use various lordotic cage sizes to help restore intervertebral disk height, correct sagittal alignment, and improve fusion rates. The use of standalone devices has consistently raised doubts due to the high risk of complications and inadequate functional recovery that a circumferential arthrodesis can support. The recent introduction of a novel XLIF cage with adapted lateral plate fixation (XLPF) may further enhance the structural rigidity, consolidating the cage and plate into a singular modular entity. Nine patients from our surgical centers underwent a procedure of 1-level XLIF with XLPF in selected cases. We observed that XLPF does not extend the intraoperative footprint and provides immediate rigidity to the anterior column without any additional risk of complications and with minimal increased time compared to the traditional cage implant procedure. Although it has been shown that the use of interbody fusion cages with supplemental posterior fixation improves stabilization in all directions, the technique of standalone lateral cages may also have a place in spine surgery in that the stability may be sufficient in selected cases, such as junctional syndrome and in some forms of degenerative scoliosis.

The authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or nonfinancial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript. The authors confirm their adherence to ethical standards and have no financial disclosures that would be potential conflicts of interest with this publication.

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Abbreviations

ALIF:

Anterior lumbar interbody fusions

MISS:

Minimally invasive spine surgery

PLF:

Posterolateral lumbar fusion

PLIF:

Posterior lumbar interbody fusion

TLIF:

Transforaminal lumbar interbody fusion

XLIF:

Extreme lateral interbody fusion

References

  1. Armocida D, Pesce A, Cimatti M, Proietti L, Santoro A, Frati A. Minimally invasive transforaminal lumbar interbody fusion using expandable cages: increased risk of late postoperative subsidence without a real improvement of perioperative outcomes: a clinical monocentric study. World Neurosurg. 2021;156:e57–63. https://doi.org/10.1016/j.wneu.2021.08.127. Epub 2021 Sep 4. PMID: 34492389.

    Article  PubMed  Google Scholar 

  2. Barone G, Scaramuzzo L, Zagra A, Giudici F, Perna A, Proietti L. Adult spinal deformity: effectiveness of interbody lordotic cages to restore disc angle and spino-pelvic parameters through completely mini-invasive trans-psoas and hybrid approach. Eur Spine J. 2017;26(Suppl 4):457–63. https://doi.org/10.1007/s00586-017-5136-1. Epub 2017 May 18. PMID: 28523382.

    Article  PubMed  Google Scholar 

  3. Proietti L, Perna A, Ricciardi L, Fumo C, Santagada DA, Giannelli I, Tamburrelli FC, Leone A. Radiological evaluation of fusion patterns after lateral lumbar interbody fusion: institutional case series. Radiol Med. 2021;126(2):250–7. https://doi.org/10.1007/s11547-020-01252-5. Epub 2020 Jul 11. PMID: 32654029.

    Article  PubMed  Google Scholar 

  4. Sharif S, Shaikh Y, Peev N. Minimally invasive spinal surgery: how to keep out of trouble. World Neurosurg. 2018;119:517–26.

    Article  PubMed  Google Scholar 

  5. Chen E, et al. Cage subsidence and fusion rate in extreme lateral interbody fusion with and without fixation. World Neurosurg. 2019;122:e969–77.

    Article  PubMed  Google Scholar 

  6. Patel PD, Canseco JA, Houlihan N, Gabay A, Grasso G, Vaccaro AR. Overview of minimally invasive spine surgery. World Neurosurg. 2020;142:43–56. https://doi.org/10.1016/j.wneu.2020.06.043.

    Article  PubMed  Google Scholar 

  7. Basra S, Bucklen B, Muzumdar A, Khalil S, Gudipally M. A novel lateral lumbar integrated plate-spacer interbody implant: in vitro biomechanical analysis. Spine J. 2015;15:322–8.

    Article  PubMed  Google Scholar 

  8. DenHaese R, Gandhi A, Ferry C, Farmer S, Porter R. An in vitro biomechanical evaluation of a lateral lumbar interbody fusion device with integrated lateral modular plate fixation. Global Spine J. 2021;11(3):351–8. https://doi.org/10.1177/2192568220905611. Epub 2020 Feb 20. PMID: 32875868; PMCID: PMC8013934.

    Article  PubMed  Google Scholar 

  9. Ozgur BM, Aryan HE, Pimenta L, et al. Extreme lateral interbody fusion (XLIF): a novel surgical technique for anterior lumbar interbody fusion. Spine J. 2006;6:435–43.

    Article  PubMed  Google Scholar 

  10. Fogel GR, Turner AW, Dooley ZA, Cornwall GB. Biomechanical stability of lateral interbody implants and supplemental fixation in a cadaveric degenerative spondylolisthesis model. Spine (Phila Pa 1976). 2014;39(19):E1138–46. https://doi.org/10.1097/BRS.0000000000000485. PMID: 24979274.

    Article  PubMed  Google Scholar 

  11. Youssef JA, McAfee PC, Patty CA, Raley E, DeBauche S, Shucosky E, Chotikul L. Minimally invasive surgery: lateral approach interbody fusion: results and review. Spine (Phila Pa 1976). 2010;35(26 Suppl):S302–11.

    Article  PubMed  Google Scholar 

  12. Bess RS, Cornwall GB, Vance RE, Bachus KN, Brodke DS. Biomechanics of lateral arthrodesis. In: Goodrich JA, Volcan IJ, editors. Extreme lateral interbody fusion (XLIF). St. Louis: Quality Medical Publishing; 2008. p. 31–40.

    Google Scholar 

  13. Barbagallo GM, Albanese V, Raich AL, Dettori JR, Sherry N, Balsano M. Lumbar lateral interbody fusion (LLIF): comparative effectiveness and safety versus PLIF/TLIF and predictive factors affecting LLIF outcome. Evid Based Spine Care J. 2014;5(1):28–37.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Joseph JR, Smith BW, La Marca F, Park P. Comparison of complication rates of minimally invasive transforaminal lumbar interbody fusion and lateral lumbar interbody fusion: a systematic review of the literature. Neurosurg Focus. 2015;39(4):E4.

    Article  PubMed  Google Scholar 

  15. DenHaese R, Hill C, Strenge B, et al. Lateral lumbar interbody fusion with modular plate fixation: initial experience with a novel technology. Intra-op and 1-year outcomes. Paper presented at: Society of Minimally Invasive Spine Surgery (SMISS) Global Forum, Las Vegas, NV; 5–7 Nov 2015.

    Google Scholar 

  16. Smith WD, Huntington CF. Letter to the editor regarding: Dua K, Kepler CK, Huang RC, Marchenko A. Vertebral body fracture after anterolateral instrumentation and interbody fusion in two osteoporotic patients. Spine J 2010;10:e11–5. Spine J. 2011;11(2):166–7; author reply 167. https://doi.org/10.1016/j.spinee.2010.12.008. PMID: 21296303.

    Article  PubMed  Google Scholar 

  17. Dua K, Kepler CK, Huang RC, Marchenko A. Vertebral body fracture after anterolateral instrumentation and interbody fusion in two osteoporotic patients. Spine J. 2010;10(9):e11–5. https://doi.org/10.1016/j.spinee.2010.07.007. PMID: 20797649.

    Article  PubMed  Google Scholar 

  18. Reis MT, Reyes PM, Bse, Altun I, Newcomb AG, Singh V, Chang SW, Kelly BP, Crawford NR. Biomechanical evaluation of lateral lumbar interbody fusion with secondary augmentation. J Neurosurg Spine. 2016;25(6):720–6. https://doi.org/10.3171/2016.4.SPINE151386. Epub 2016 Jul 8. PMID: 27391398.

    Article  PubMed  Google Scholar 

  19. Ge T, Ao J, Li G, Lang Z, Sun Y. Additional lateral plate fixation has no effect to prevent cage subsidence in oblique lumbar interbody fusion. J Orthop Surg Res. 2021;16(1):584. https://doi.org/10.1186/s13018-021-02725-7. PMID: 34635143; PMCID: PMC8507130.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Kaneda K, Taneichi H, Abumi K, et al. Anterior decompression and stabilization with the Kaneda device for thoracolumbar burst fractures associated with neurological deficits. J Bone Joint Surg Am. 1997;79:69–83.

    Article  CAS  PubMed  Google Scholar 

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We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. We wish to draw the attention of the editor to the following facts, which may be considered as potential conflicts of interest, and to the significant financial contributions to this work.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

This article does not contain any studies with animals performed by any of the authors.

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Armocida, D. et al. (2023). Extreme Lateral Interbody Fusion (XLIF) with Lateral Modular Plate Fixation: Preliminary Report on Clinical and Radiological Outcomes. In: Visocchi, M. (eds) The Funnel: From the Skull Base to the Sacrum. Acta Neurochirurgica Supplement, vol 135. Springer, Cham. https://doi.org/10.1007/978-3-031-36084-8_66

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  • DOI: https://doi.org/10.1007/978-3-031-36084-8_66

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