Skip to main content

Post-mortem Imaging of Brain/Spine Injuries: The Importance of a Comprehensive Forensic Approach

  • Chapter
  • First Online:
The Funnel: From the Skull Base to the Sacrum

Abstract

In forensic investigations, the limitations of the traditional purely autoptic approach can be overcome through post-mortem imaging (virtopsy). Virtospy has several applications to the investigation of brain and spinal injuries, whose analysis can be of forensic interest, especially in cases of suspected malpractice. In this scoping review, we briefly describe the main applications of the two most common post-mortem radiological techniques (computed tomography (CT) and magnetic resonance imaging (MRI)) to the forensic investigation of brain and spinal injuries in cases of medical malpractice or traumatic (accidental/homicidal/suicidal) deaths. Although CT represents the traditional approach to post-mortem imaging, MRI is proving to be a valuable tool to investigate brain and spinal injuries and lesions. These post-mortem radiological techniques can also be used to guide the surgeons in simulated surgical procedures on corpses in the context of training programs, thus helping operators to improve technical and non-technical skills and to reduce the risk of avoidable errors.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Oliva A, Grassi S, Grassi VM, Pinchi V, Floris R, Manenti G, Colosimo C, Filograna L, Pascali VL. Postmortem CT and autopsy findings in nine victims of terrorist attack. Int J Legal Med. 2021;135:605. https://doi.org/10.1007/s00414-020-02492-w.

    Article  PubMed  Google Scholar 

  2. Thali MJ, Jackowski C, Oesterhelweg L, Ross SG, Dirnhofer R. VIRTOPSY – The Swiss virtual autopsy approach. Legal Med. 2007;9:100. https://doi.org/10.1016/j.legalmed.2006.11.011.

    Article  PubMed  Google Scholar 

  3. Araki A, Ishikawa N, Takami S, Ishikawa N, Amano C, Takeshita H, Maruyama R. Interpretation of postmortem head computed tomography for non-traumatic in-hospital deaths by non-radiologists: a preliminary study. Springerplus. 2016;5:978. https://doi.org/10.1186/s40064-016-2653-z.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Filograna L, Manenti G, Arena V, Dell’Aquila M, Pascali VL, Natale L, Colosimo C, Grassi S, Floris R, Oliva A. Claimed medical malpractice in fatal SARS-CoV-2 infections: the importance of combining ante- and post-mortem radiological data and autopsy findings for correct forensic analysis. Forens Imaging. 2021;25:200454. https://doi.org/10.1016/j.fri.2021.200454.

    Article  Google Scholar 

  5. Mizuno J, Nakagawa H, Chang H-S, Hashizume Y. Postmortem study of the spinal cord showing snake-eyes appearance due to damage by ossification of the posterior longitudinal ligament and kyphotic deformity. Spinal Cord. 2005;43:503. https://doi.org/10.1038/sj.sc.3101727.

    Article  CAS  PubMed  Google Scholar 

  6. Someya Y, Koda M, Hashimoto M, Okawa A, Masaki Y, Yamazaki M. Postmortem findings in a woman with history of laminoplasty for severe cervical spondylotic myelopathy. J Spin Cord Med. 2011;34:523. https://doi.org/10.1179/107902611X13069205199503.

    Article  Google Scholar 

  7. Wagensveld IM, Hunink MGM, Wielopolski PA, van Kemenade FJ, Krestin GP, Blokker BM, Oosterhuis JW, Weustink AC. Hospital implementation of minimally invasive autopsy: a prospective cohort study of clinical performance and costs. PLoS One. 2019;14:e0219291. https://doi.org/10.1371/journal.pone.0219291.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Heinemann A, Vogel H, Heller M, Tzikas A, Püschel K. Investigation of medical intervention with fatal outcome: the impact of post-mortem CT and CT angiography. Radiol Med. 2015;120:835. https://doi.org/10.1007/s11547-015-0574-5.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Bertozzi G, Maglietta F, Sessa F, Scoto E, Cipolloni L, di Mizio G, Salerno M, Pomara C. Traumatic brain injury: a forensic approach: a literature review. Curr Neuropharmacol. 2020;18:538. https://doi.org/10.2174/1570159X17666191101123145.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Signorelli F, Stumpo V, Della Pepa GM, la Rocca G, Oliva A, Olivi A, Visocchi M. Step-up establishment of neurosurgical laboratory starting with limited resources—tips and tricks. World Neurosurg. 2019;126:83. https://doi.org/10.1016/j.wneu.2019.02.034.

    Article  PubMed  Google Scholar 

  11. Persson A, Falk J, Berge J, Jackowski C. Atlanto-axial rotatory subluxations in postmortem CT: radiologists be aware of a common pitfall. Forensic Sci Int. 2013;225:9. https://doi.org/10.1016/j.forsciint.2013.01.001.

    Article  CAS  PubMed  Google Scholar 

  12. Sutherland T, O’Donnell C. The artefacts of death: CT post-mortem findings. J Med Imaging Radiat Oncol. 2018;62:203. https://doi.org/10.1111/1754-9485.12691.

    Article  PubMed  Google Scholar 

  13. Thayyil S, Sebire NJ, Chitty LS, Wade A, Chong W, Olsen O, Gunny RS, Offiah AC, Owens CM, Saunders DE, et al. Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study. Lancet. 2013;382:223. https://doi.org/10.1016/S0140-6736(13)60134-8.

    Article  PubMed  Google Scholar 

  14. Stäbler A, Eck J, Penning R, Milz SP, Bartl R, Resnick D, Reiser M. Cervical spine: postmortem assessment of accident injuries—comparison of radiographic, MR imaging, anatomic, and pathologic findings. Radiology. 2001;221:340. https://doi.org/10.1148/radiol.2212010336.

    Article  PubMed  Google Scholar 

  15. Atesok K, Tanaka N, O’Brien A, Robinson Y, Pang D, Deinlein D, Manoharan SR, Pittman J, Theiss S. Posttraumatic spinal cord injury without radiographic abnormality. Adv Orthop. 2018;2018:7060654. https://doi.org/10.1155/2018/7060654.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Gascho D, Deininger-Czermak E, Zoelch N, Tappero C, Sommer S, Hinterholzer N, Thali MJ. Noninvasive 7 tesla MRI of fatal craniocerebral gunshots – a glance into the future of radiologic wound ballistics. Forens Sci Med Pathol. 2020;16:595. https://doi.org/10.1007/s12024-020-00300-w.

    Article  Google Scholar 

  17. Calabrese E, Adil SM, Cofer G, Perone CS, Cohen-Adad J, Lad SP, Johnson GA. Postmortem diffusion MRI of the entire human spinal cord at microscopic resolution. NeuroImage Clin. 2018;18:963. https://doi.org/10.1016/j.nicl.2018.03.029.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Coolen T, Lolli V, Sadeghi N, Rovai A, Trotta N, Taccone FS, Creteur J, Henrard S, Goffard J-C, Dewitte O, et al. Early postmortem brain MRI findings in COVID-19 non-survivors. Neurology. 2020;95:e2016. https://doi.org/10.1212/WNL.0000000000010116.

    Article  CAS  PubMed  Google Scholar 

  19. Alkemade A, Groot JM, Forstmann BU. Do we need a human post mortem whole-brain anatomical ground truth in in vivo magnetic resonance imaging? Front Neuroanat. 2018;12:110. https://doi.org/10.3389/fnana.2018.00110.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Bodmer A, Ross S, Raabe A, Beck J, Ulrich C, Schucht P. Virtual autopsy to assess sacral anatomy: conditions for a minimal invasive approach to the spinal canal through the Hiatus Sacralis. Surg Neurol Int. 2017;8:290. https://doi.org/10.4103/sni.sni_313_17.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Signorelli F, Stumpo V, Oliva A, Pascali VL, Olivi A, Visocchi M. Mastering craniovertebral junction surgical approaches: the dissection laboratory experience at the Catholic University of Rome. Acta Neurochir Suppl. 2019;125:13.

    Article  PubMed  Google Scholar 

  22. Visocchi M, Barbagallo G, Pascali VL, Mattogno P, Signorelli F, Iacopino G, Germano’ A, la Rocca G. Craniovertebral junction transanasal and transoral approaches: reconstruct the surgical pathways with soft or hard tissue endocopic lines? This Is the Question. Acta Neurochir Suppl. 2017;124:117.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Antonio Oliva .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Azmitia, L. et al. (2023). Post-mortem Imaging of Brain/Spine Injuries: The Importance of a Comprehensive Forensic Approach. In: Visocchi, M. (eds) The Funnel: From the Skull Base to the Sacrum. Acta Neurochirurgica Supplement, vol 135. Springer, Cham. https://doi.org/10.1007/978-3-031-36084-8_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-36084-8_6

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-36083-1

  • Online ISBN: 978-3-031-36084-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics