Abstract
In forensic investigations, the limitations of the traditional purely autoptic approach can be overcome through post-mortem imaging (virtopsy). Virtospy has several applications to the investigation of brain and spinal injuries, whose analysis can be of forensic interest, especially in cases of suspected malpractice. In this scoping review, we briefly describe the main applications of the two most common post-mortem radiological techniques (computed tomography (CT) and magnetic resonance imaging (MRI)) to the forensic investigation of brain and spinal injuries in cases of medical malpractice or traumatic (accidental/homicidal/suicidal) deaths. Although CT represents the traditional approach to post-mortem imaging, MRI is proving to be a valuable tool to investigate brain and spinal injuries and lesions. These post-mortem radiological techniques can also be used to guide the surgeons in simulated surgical procedures on corpses in the context of training programs, thus helping operators to improve technical and non-technical skills and to reduce the risk of avoidable errors.
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References
Oliva A, Grassi S, Grassi VM, Pinchi V, Floris R, Manenti G, Colosimo C, Filograna L, Pascali VL. Postmortem CT and autopsy findings in nine victims of terrorist attack. Int J Legal Med. 2021;135:605. https://doi.org/10.1007/s00414-020-02492-w.
Thali MJ, Jackowski C, Oesterhelweg L, Ross SG, Dirnhofer R. VIRTOPSY – The Swiss virtual autopsy approach. Legal Med. 2007;9:100. https://doi.org/10.1016/j.legalmed.2006.11.011.
Araki A, Ishikawa N, Takami S, Ishikawa N, Amano C, Takeshita H, Maruyama R. Interpretation of postmortem head computed tomography for non-traumatic in-hospital deaths by non-radiologists: a preliminary study. Springerplus. 2016;5:978. https://doi.org/10.1186/s40064-016-2653-z.
Filograna L, Manenti G, Arena V, Dell’Aquila M, Pascali VL, Natale L, Colosimo C, Grassi S, Floris R, Oliva A. Claimed medical malpractice in fatal SARS-CoV-2 infections: the importance of combining ante- and post-mortem radiological data and autopsy findings for correct forensic analysis. Forens Imaging. 2021;25:200454. https://doi.org/10.1016/j.fri.2021.200454.
Mizuno J, Nakagawa H, Chang H-S, Hashizume Y. Postmortem study of the spinal cord showing snake-eyes appearance due to damage by ossification of the posterior longitudinal ligament and kyphotic deformity. Spinal Cord. 2005;43:503. https://doi.org/10.1038/sj.sc.3101727.
Someya Y, Koda M, Hashimoto M, Okawa A, Masaki Y, Yamazaki M. Postmortem findings in a woman with history of laminoplasty for severe cervical spondylotic myelopathy. J Spin Cord Med. 2011;34:523. https://doi.org/10.1179/107902611X13069205199503.
Wagensveld IM, Hunink MGM, Wielopolski PA, van Kemenade FJ, Krestin GP, Blokker BM, Oosterhuis JW, Weustink AC. Hospital implementation of minimally invasive autopsy: a prospective cohort study of clinical performance and costs. PLoS One. 2019;14:e0219291. https://doi.org/10.1371/journal.pone.0219291.
Heinemann A, Vogel H, Heller M, Tzikas A, Püschel K. Investigation of medical intervention with fatal outcome: the impact of post-mortem CT and CT angiography. Radiol Med. 2015;120:835. https://doi.org/10.1007/s11547-015-0574-5.
Bertozzi G, Maglietta F, Sessa F, Scoto E, Cipolloni L, di Mizio G, Salerno M, Pomara C. Traumatic brain injury: a forensic approach: a literature review. Curr Neuropharmacol. 2020;18:538. https://doi.org/10.2174/1570159X17666191101123145.
Signorelli F, Stumpo V, Della Pepa GM, la Rocca G, Oliva A, Olivi A, Visocchi M. Step-up establishment of neurosurgical laboratory starting with limited resources—tips and tricks. World Neurosurg. 2019;126:83. https://doi.org/10.1016/j.wneu.2019.02.034.
Persson A, Falk J, Berge J, Jackowski C. Atlanto-axial rotatory subluxations in postmortem CT: radiologists be aware of a common pitfall. Forensic Sci Int. 2013;225:9. https://doi.org/10.1016/j.forsciint.2013.01.001.
Sutherland T, O’Donnell C. The artefacts of death: CT post-mortem findings. J Med Imaging Radiat Oncol. 2018;62:203. https://doi.org/10.1111/1754-9485.12691.
Thayyil S, Sebire NJ, Chitty LS, Wade A, Chong W, Olsen O, Gunny RS, Offiah AC, Owens CM, Saunders DE, et al. Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study. Lancet. 2013;382:223. https://doi.org/10.1016/S0140-6736(13)60134-8.
Stäbler A, Eck J, Penning R, Milz SP, Bartl R, Resnick D, Reiser M. Cervical spine: postmortem assessment of accident injuries—comparison of radiographic, MR imaging, anatomic, and pathologic findings. Radiology. 2001;221:340. https://doi.org/10.1148/radiol.2212010336.
Atesok K, Tanaka N, O’Brien A, Robinson Y, Pang D, Deinlein D, Manoharan SR, Pittman J, Theiss S. Posttraumatic spinal cord injury without radiographic abnormality. Adv Orthop. 2018;2018:7060654. https://doi.org/10.1155/2018/7060654.
Gascho D, Deininger-Czermak E, Zoelch N, Tappero C, Sommer S, Hinterholzer N, Thali MJ. Noninvasive 7 tesla MRI of fatal craniocerebral gunshots – a glance into the future of radiologic wound ballistics. Forens Sci Med Pathol. 2020;16:595. https://doi.org/10.1007/s12024-020-00300-w.
Calabrese E, Adil SM, Cofer G, Perone CS, Cohen-Adad J, Lad SP, Johnson GA. Postmortem diffusion MRI of the entire human spinal cord at microscopic resolution. NeuroImage Clin. 2018;18:963. https://doi.org/10.1016/j.nicl.2018.03.029.
Coolen T, Lolli V, Sadeghi N, Rovai A, Trotta N, Taccone FS, Creteur J, Henrard S, Goffard J-C, Dewitte O, et al. Early postmortem brain MRI findings in COVID-19 non-survivors. Neurology. 2020;95:e2016. https://doi.org/10.1212/WNL.0000000000010116.
Alkemade A, Groot JM, Forstmann BU. Do we need a human post mortem whole-brain anatomical ground truth in in vivo magnetic resonance imaging? Front Neuroanat. 2018;12:110. https://doi.org/10.3389/fnana.2018.00110.
Bodmer A, Ross S, Raabe A, Beck J, Ulrich C, Schucht P. Virtual autopsy to assess sacral anatomy: conditions for a minimal invasive approach to the spinal canal through the Hiatus Sacralis. Surg Neurol Int. 2017;8:290. https://doi.org/10.4103/sni.sni_313_17.
Signorelli F, Stumpo V, Oliva A, Pascali VL, Olivi A, Visocchi M. Mastering craniovertebral junction surgical approaches: the dissection laboratory experience at the Catholic University of Rome. Acta Neurochir Suppl. 2019;125:13.
Visocchi M, Barbagallo G, Pascali VL, Mattogno P, Signorelli F, Iacopino G, Germano’ A, la Rocca G. Craniovertebral junction transanasal and transoral approaches: reconstruct the surgical pathways with soft or hard tissue endocopic lines? This Is the Question. Acta Neurochir Suppl. 2017;124:117.
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Azmitia, L. et al. (2023). Post-mortem Imaging of Brain/Spine Injuries: The Importance of a Comprehensive Forensic Approach. In: Visocchi, M. (eds) The Funnel: From the Skull Base to the Sacrum. Acta Neurochirurgica Supplement, vol 135. Springer, Cham. https://doi.org/10.1007/978-3-031-36084-8_6
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