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Candidiasis

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Diagnosis and Treatment of Fungal Infections

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Abstract

Multiple pathogenic species of Candida are responsible for a myriad of superficial and systemic or deep clinical syndromes that constitute candidiasis. Recent epidemiologic shifts in causative Candida species reflect the impact of use of several groups or classes of antimycotic drugs, as well as the increase of at-risk and immunocompromised hosts. Newly introduced diagnostic tests facilitate earlier use of antifungal agents with improved clinical outcomes and reduced morbidity and mortality. The increased appearance of non-albicans Candida species has created an increased challenge to selecting early appropriate antifungal drug therapy. Since the introduction of the echinocandins class of drugs, new in vitro and clinical resistance of certain Candida species, notably C. glabrata has emerged to this class as well, creating the need for more rapid species identification to ensure the rapid use of appropriate antimycotic therapy.

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Author information

Authors and Affiliations

  1. Division of Infectious Diseases, McGovern Medical School, Houston, TX, USA

    Luis Ostrosky-Zeichner

  2. Mott Center for Human Growth and Development, School of Medicine, Wayne State University, Detroit, MI, USA

    Jack D. Sobel

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  1. Luis Ostrosky-Zeichner
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  2. Jack D. Sobel
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Correspondence to Luis Ostrosky-Zeichner .

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Editors and Affiliations

  1. Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    Duane R. Hospenthal

  2. Departments of Pathology, Microbiology, and Clinical Laboratory Sciences, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    Michael G. Rinaldi

  3. Departments of Medicine and Microbiology & Immunology, University of Maryland School of Medicine, Baltimore, MD, USA

    Thomas J. Walsh

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Ostrosky-Zeichner, L., Sobel, J.D. (2023). Candidiasis. In: Hospenthal, D.R., Rinaldi, M.G., Walsh, T.J. (eds) Diagnosis and Treatment of Fungal Infections. Springer, Cham. https://doi.org/10.1007/978-3-031-35803-6_9

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  • DOI: https://doi.org/10.1007/978-3-031-35803-6_9

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