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Onion

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Essentials of Medicinal and Aromatic Crops

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Abstract

Allium cepa L. (onion) is the oldest known vegetable used in cooking and fresh salads. Onion is placed in the monocot family of herbaceous plants with order Asparagales. It is mainly cultivated for edible bulb, with pungent aste and odour, its leaves above ground are also consumed. The inflorescence is compound umbel and root system is fibrous and shallow. It contains various organosulphur compounds, phenolics, saponins and polysaccharides with Quercetin as a major bioactive compound. It shows various pharmacological properties. Onion peel and bulb have therapeutic effects for treating oxidative stress, inflammation and immune dysregulation. The use of onion is inversely proportional to the glucose levels due to the presence of volatile oil allyl propyl disulfide, it lowers blood sugar level by enhancing the availability of free insulin. The use of novel methods in onion production have led to the major changes and opportunities for the onion production.

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References

  1. Arshad, M. S., et al. (2017). Status and trends of nutraceuticals from onion and onion by-products: A critical review. Cogent Food & Agriculture, 3(1), 1280254.

    Article  Google Scholar 

  2. Rabinowitch, H., & Kamenetsky, R. (2002). 17 shallot (Allium cepa, Aggregatum Group). Allium Crop Science: Recent Advances, 409.

    Google Scholar 

  3. Wiart, C. (2019). Medicinal plants of Bangladesh and West Bengal: Botany, natural products, & ethnopharmacology. CRC Press.

    Book  Google Scholar 

  4. Khare, C. P. (2008). Indian medicinal plants: An illustrated dictionary. Springer.

    Google Scholar 

  5. Jaime, L., et al. (2002). Structural carbohydrate differences and potential source of dietary fiber of onion (Allium cepa L.) tissues. Journal of Agricultural and Food Chemistry, 50(1), 122–128.

    Article  CAS  PubMed  Google Scholar 

  6. Shiomi, N., Benkeblia, N., & Onodera, S. (2005). The metabolism of the fructooligosaccharides in onion bulbs: A comprehensive review. Journal of Applied Glycoscience, 52(2), 121–127.

    Article  CAS  Google Scholar 

  7. Baldwin, S., et al. (2014). Genetic analyses of bolting in bulb onion (Allium cepa L.). Theoretical and Applied Genetics, 127, 535–547.

    Article  CAS  PubMed  Google Scholar 

  8. Villanueva-Mosqueda, E., & Havey, M. J. (2001). Genetic analyses of seed yield in onion. Journal of the American Society for Horticultural Science, 126(5), 575–578.

    Article  Google Scholar 

  9. Caruso, G., et al. (2014). Effects of transplanting time and plant density on yield, quality and antioxidant content of onion (Allium cepa L.) in southern Italy. Scientia Horticulturae, 166, 111–120.

    Article  CAS  Google Scholar 

  10. Dilpreet, T. (2016). Growth, yield and quality of onion as influenced by integrated nutrient management. International Journal of Agriculture Sciences, 0975–3710.

    Google Scholar 

  11. Jackson, K., et al. (1997). Onion information kit. Agrilink, your growing guide to better farming guide.

    Google Scholar 

  12. Werner, C., et al. (1990). Prediction of the performance of inbred lines derived from a population cross in autumn-sown onions (Allium cepa L.). Theoretical and Applied Genetics, 79, 507–512.

    Article  CAS  PubMed  Google Scholar 

  13. Moore, S. R. (2010). Energy efficiency in small-scale biointensive organic onion production in Pennsylvania, USA. Renewable Agriculture and Food Systems, 25(3), 181–188.

    Article  Google Scholar 

  14. Boyhan, G. E., et al. (2009). Sowing date, transplanting date, and variety effect on transplanted short-day onion production. HortTechnology, 19(1), 66–71.

    Article  Google Scholar 

  15. Elhami, B., et al. (2021). Analysis and comparison of energy-economic-environmental cycle in two cultivation methods (seeding and transplanting) for onion production (case study: Central parts of Iran). Renewable Energy, 178, 875–890.

    Article  Google Scholar 

  16. Syverson, P., et al. (2001). Towards an analysis of onion routing security. In Designing privacy enhancing technologies: International workshop on design issues in anonymity and Unobservability Berkeley, CA, USA, July 25–26, 2000 proceedings. Springer.

    Google Scholar 

  17. Kumar, S., et al. (2007). Response of onion (Allium cepa L.) to different levels of irrigation water. Agricultural Water Management, 89(1-2), 161–166.

    Article  Google Scholar 

  18. Esmaeilzadeh, S., Asgharipour, M. R., & Khoshnevisan, B. (2020). Water footprint and life cycle assessment of edible onion production – A case study in Iran. Scientia Horticulturae, 261, 108925.

    Article  Google Scholar 

  19. Schwimmer, S., & Weston, W. J. (1961). Onion flavor and odor, enzymatic development of pyruvic acid in onion as a measure of pungency. Journal of Agricultural and Food Chemistry, 9(4), 301–304.

    Article  Google Scholar 

  20. Lancaster, J., & Boland, M. (1990). Chapter 3: Flavour biochemistry. In Onions and allied crops (Vol. III). CRC Press.

    Google Scholar 

  21. Whitaker, J. R. (1976). Development of flavor, odor, and pungency in onion and garlic. In Advances in food research (pp. 73–133). Elsevier.

    Google Scholar 

  22. Griffiths, G., et al. (2002). Onions – A global benefit to health. Phytotherapy Research, 16(7), 603–615.

    Article  CAS  PubMed  Google Scholar 

  23. Lanzotti, V. (2006). The analysis of onion and garlic. Journal of Chromatography A, 1112(1–2), 3–22.

    Article  CAS  PubMed  Google Scholar 

  24. Boyhan, G. E., Torrance, R. L., & Hill, C. R. (2007). Effects of nitrogen, phosphorus, and potassium rates and fertilizer sources on yield and leaf nutrient status of short-day onions. HortScience, 42(3), 653–660.

    Article  CAS  Google Scholar 

  25. Dorokhov, A., et al. (2021). Determining the speed of soil particles during the covering of set onion with a disk-type working element featuring a soil guide. In E3S web of conferences. EDP Sciences.

    Google Scholar 

  26. Schwartz, H. F., et al. (2014). Onion ipm PIPE: A coordinated effort to improve the management of onion thrips and Iris yellow spot virus for the US onion industry. Plant Health Progress, 15(4), 172–183.

    Article  Google Scholar 

  27. Khokhar, K. M. (2017). Environmental and genotypic effects on bulb development in onion – a review. The Journal of Horticultural Science and Biotechnology, 92(5), 448–454.

    Article  CAS  Google Scholar 

  28. Boyhan, G., & Kelley, W. (2007). Onion production guide (Bulletin 1198). The University of Georgia Cooperative Extension Service.

    Google Scholar 

  29. Brice, J., et al. (1997). Onion storage in the tropics: A practical guide to methods of storage and their selection. Natural Resources Institute.

    Google Scholar 

  30. Thuong, T. T. (2015). Factors affecting the storage decision of onion farmers in Kinh Mon District, Hai Duong Province, Vietnam. Journal of Economics, Management & Agricultural Development.

    Google Scholar 

  31. Tyson, C. (2021). Onion producers guide (pp. 1–48).

    Google Scholar 

  32. Díaz-Pérez, J. C., Purvis, A. C., & Paulk, J. T. (2003). Bolting, yield, and bulb decay of sweet onion as affected by nitrogen fertilization. Journal of the American Society for Horticultural Science, 128(1), 144–149.

    Article  Google Scholar 

  33. Wall, M., Mohammad, A., & Corgan, J. (1996). Heritability estimates and response to selection for the pungency and single center traits in onion. Euphytica, 87, 133–139.

    Article  Google Scholar 

  34. Taylor, A. G., Eckenrode, C., & Straub, R. (2001). Seed coating technologies and treatments for onion: Challenges and progress. HortScience, 36(2), 199–205.

    Article  CAS  Google Scholar 

  35. Walkey, D., et al. (1987). Production of virus-free garlic (Allium sativum L.) and shallot (A. ascalonicum L.) by meristem-tip culture. Journal of Horticultural Science, 62(2), 211–220.

    Article  Google Scholar 

  36. Yoo, K. S., & Pike, L. M. (1998). Determination of flavor precursor compound S-alk (en) yl-L-cysteine sulfoxides by an HPLC method and their distribution in Allium species. Scientia Horticulturae, 75(1-2), 1–10.

    Article  Google Scholar 

  37. Wilkie, S. E., Isaac, P. G., & Slater, R. J. (1993). Random amplified polymorphic DNA (RAPD) markers for genetic analysis in Allium. Theoretical and Applied Genetics, 86, 497–504.

    Article  CAS  PubMed  Google Scholar 

  38. Fujiwara, K., et al. (2021). Real-time PCR detection of the onion downy mildew pathogen Peronospora destructor from symptomless onion seedlings and soils. Plant Disease, 105(3), 643–649.

    Article  CAS  PubMed  Google Scholar 

  39. Khan, P. S. S. V., et al. (2020). Doubled haploid production in onion (Allium cepa L.): From gynogenesis to chromosome doubling. Plant Cell, Tissue and Organ Culture (PCTOC), 142, 1–22.

    Article  CAS  Google Scholar 

  40. Martínez, L. (2003). In vitro gynogenesis induction and doubled haploid production in onion (Allium cepa L.). Doubled Haploid Production in Crop Plants: A Manual, 275–279.

    Google Scholar 

  41. Kim, S., Yoo, K. S., & Pike, L. M. (2007). Production of doubled haploid onions (Allium cepa) and evaluation of their field performance. Horticulture Environment and Biotechnology, 48(3), 143–147.

    Google Scholar 

  42. Dhatt, A., & Thakur, P. (2014). Production of doubled haploids in onion: A review. Journal of Horticultural Sciences, 9(2), 107–112.

    Article  Google Scholar 

  43. Khar, A., et al. (2019). Present status of haploidy research in onion (Allium cepa) – A review. Indian Journal of Agricultural Sciences, 89, 396–405.

    Article  CAS  Google Scholar 

  44. Khar, A., et al. (2018). Genotypic response towards haploid induction in short day tropical Indian onion (Allium cepa). Indian Journal of Agricultural Sciences, 88(5), 709–713.

    Article  CAS  Google Scholar 

  45. Bohanec, B., Jakse, M., & Havey, M. J. (2003). Genetic analyses of gynogenetic haploid production in onion. Journal of the American Society for Horticultural Science, 128(4), 571–574.

    Article  Google Scholar 

  46. Eady, C., Weld, R., & Lister, C. (2000). Agrobacterium tumefaciens-mediated transformation and transgenic-plant regeneration of onion (Allium cepa L.). Plant Cell Reports, 19, 376–381.

    Article  CAS  PubMed  Google Scholar 

  47. Ueno, S., et al. (2009). High-pressure induced transformation of onion. Japan Journal of Food Engineering, 10(1), 37–43.

    Article  Google Scholar 

  48. Vernon, R. S., Judd, G., & Borden, J. (1987). Commercial monitoring programme for the onion fly, Delia antiqua (Meigen) (Diptera: Anthomyiidae) in South-Western British Columbia. Crop Protection, 6(5), 304–312.

    Article  Google Scholar 

  49. Das, A. K., Hasan, W., & Singh, S. K. (2017). Management of onion thrips, Thrips tabaci using chemical and bio-pesticide for quality onion production. Trends in Biosciences, 10(22), 4384–4388.

    Google Scholar 

  50. Black, L., et al. (2012). Onion disease guide. A practical guide for seedsmen, growers and agricultural advisors. Seminis Vegetable Seeds.

    Google Scholar 

  51. Boelens, M., et al. (1971). Volatile flavor compounds from onion. Journal of Agricultural and Food Chemistry, 19(5), 984–991.

    Article  CAS  Google Scholar 

  52. Brewster, J. L. (2008). Onions and other vegetable alliums (Vol. 15). CABI.

    Book  Google Scholar 

  53. George, E. S., et al. (2018). A Mediterranean diet model in Australia: Strategies for translating the traditional Mediterranean diet into a multicultural setting. Nutrients, 10(4), 465.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Gebhardt, R., Beck, H., & Wagner, K. G. (1994). Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells. Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism, 1213(1), 57–62.

    Article  CAS  PubMed  Google Scholar 

  55. Glässer, G., et al. (2002). Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites. Phytomedicine, 9(1), 33–40.

    Article  PubMed  Google Scholar 

  56. Goldman, I. L., et al. (1996). Antiplatelet activity in onion (Allium cepa) is sulfur dependent. Thrombosis and Haemostasis, 76(09), 450–452.

    CAS  PubMed  Google Scholar 

  57. Gao, C. M., et al. (1999). Protective effect of allium vegetables against both esophageal and stomach cancer: A simultaneous case-referent study of a high-epidemic area in Jiangsu Province, China. Japanese Journal of Cancer Research, 90(6), 614–621.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  58. Warid, W., & Tims, E. (1952). Studies on the inheritance of resistance to downy mildew studies in onion incited by Peronospora destructor. Phytopathology, 42, 22.

    Google Scholar 

  59. Walker, J., Jones, H., & Clarke, A. (1944). Smut resistance in an Allium species hybrid.

    Google Scholar 

  60. Warid, W. A. B. (1952). Inheritance studies in the onion, Allium cepa L. Louisiana State University.

    Google Scholar 

  61. Goldschlag, D., Reed, M., & Syverson, P. (1999). Onion routing. Communications of the ACM, 42(2), 39–41.

    Article  Google Scholar 

  62. Whitwell, J., & Frith, L. (1973). Experiments on the use of maleic hydrazide as a sprout suppressant on spring sown bulb onions. Experimental Horticulture.

    Google Scholar 

  63. Gulati, A., Wardhan, H., & Sharma, P. (2022). Tomato, Onion and Potato (TOP) value chains. Agricultural Value Chains in India: Ensuring Competitiveness, Inclusiveness, Sustainability, Scalability, and Improved Finance, 33–97.

    Google Scholar 

  64. Dong, J., et al. (2022). Global vegetable supply towards sustainable food production and a healthy diet. Journal of Cleaner Production, 369, 133212.

    Article  Google Scholar 

  65. Ariga, T., et al. (2000). Antithrombotic and antineoplastic effects of phyto-organosulfur compounds. BioFactors, 13(1-4), 251–255.

    Article  CAS  PubMed  Google Scholar 

  66. Augusti, K., et al. (1975). Partial identification of the fibrinolytic activators in onion. Atherosclerosis, 21(3), 409–416.

    Article  CAS  PubMed  Google Scholar 

  67. Bajaj, J. S., Shaker, R., & Hogan, W. J. (2004). Esophageal veggie spasms: A food-specific cause of chest distress. Official Journal of the American College of Gastroenterology | ACG, 99(7), 1396–1398.

    Article  Google Scholar 

  68. Bianchini, F., & Vainio, H. (2001). Allium vegetables and organosulfur compounds: Do they help prevent cancer? Environmental Health Perspectives, 109(9), 893–902.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. Boyle, S., et al. (2000). Absorption and DNA protective effects of flavonoid glycosides from an onion meal. European Journal of Nutrition, 39(5), 213.

    Article  CAS  PubMed  Google Scholar 

  70. Briggs, W. H., et al. (2001). Administration of raw onion inhibits platelet-mediated thrombosis in dogs. The Journal of Nutrition, 131(10), 2619–2622.

    Article  CAS  PubMed  Google Scholar 

  71. Campos, K., et al. (2003). Hypoglycaemic and antioxidant effects of onion, Allium cepa: Dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats. International Journal of Food Sciences and Nutrition, 54(3), 241–246.

    Article  CAS  PubMed  Google Scholar 

  72. Cho, J.-W., et al. (2010). Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo. International Journal of Molecular Medicine, 25(3), 347–352.

    CAS  PubMed  Google Scholar 

  73. Chung, V. Q., et al. (2006). Onion extract gel versus petrolatum emollient on new surgical scars: A prospective double-blinded study. Dermatologic Surgery, 32(2), 193–197.

    CAS  PubMed  Google Scholar 

  74. Draelos, Z. D. (2008). The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. Journal of Cosmetic Dermatology, 7(2), 101–104.

    Article  PubMed  Google Scholar 

  75. El-Demerdash, F. M., Yousef, M. I., & Abou El-Naga, N. (2005). Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food and Chemical Toxicology, 43(1), 57–63.

    Article  CAS  PubMed  Google Scholar 

  76. Gabler, N. K., et al. (2006). Dietary onion intake as part of a typical high fat diet improves indices of cardiovascular health using the mixed sex pig model. Plant Foods for Human Nutrition, 61, 179–185.

    Article  CAS  PubMed  Google Scholar 

  77. Galeone, C., et al. (2009). Allium vegetables intake and endometrial cancer risk. Public Health Nutrition, 12(9), 1576–1579.

    Article  PubMed  Google Scholar 

  78. Galeone, C., et al. (2009). Allium vegetable intake and risk of acute myocardial infarction in Italy. European Journal of Nutrition, 48, 120–123.

    Article  CAS  PubMed  Google Scholar 

  79. Graefe, E. U., et al. (2001). Pharmacokinetics and bioavailability of quercetin glycosides in humans. The Journal of Clinical Pharmacology, 41(5), 492–499.

    Article  CAS  PubMed  Google Scholar 

  80. Herman-Antosiewicz, A., & Singh, S. V. (2004). Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by allium vegetable-derived organosulfur compounds: A review. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 555(1-2), 121–131.

    Article  CAS  PubMed  Google Scholar 

  81. Hister, C., et al. (2009). Evaluation of the antiproliferative effects of infusions and essential oil of Aloysia gratissima. Pakistan Journal of Biological Sciences, 12(24).

    Google Scholar 

  82. Ho, W. S., et al. (2006). Use of onion extract, heparin, allantoin gel in prevention of scarring in Chinese patients having laser removal of tattoos: A prospective randomized controlled trial. Dermatologic Surgery, 32(7), 891–896.

    CAS  PubMed  Google Scholar 

  83. Hong, Y.-J., & Mitchell, A. E. (2004). Metabolic profiling of flavonol metabolites in human urine by liquid chromatography and tandem mass spectrometry. Journal of Agricultural and Food Chemistry, 52(22), 6794–6801.

    Article  CAS  PubMed  Google Scholar 

  84. Hosnuter, M., et al. (2007). The effects of onion extract on hypertrophic and keloid scars. Journal of Wound Care, 16(6), 251–254.

    Article  CAS  PubMed  Google Scholar 

  85. Huang, T.-H., et al. (2008). Onion decreases the ovariectomy-induced osteopenia in young adult rats. Bone, 42(6), 1154–1163.

    Article  CAS  PubMed  Google Scholar 

  86. Hubbard, G. P., et al. (2006). Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: A pilot study. British Journal of Nutrition, 96(3), 482–488.

    Article  CAS  PubMed  Google Scholar 

  87. Jalili, T., et al. (2006). Quercetin-supplemented diets lower blood pressure and attenuate cardiac hypertrophy in rats with aortic constriction. Journal of Cardiovascular Pharmacology, 47(4), 531–541.

    Article  CAS  PubMed  Google Scholar 

  88. Jung, Y.-S., et al. (2002). Antithrombotic effect of onion in streptozotocin-induced diabetic rat. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 66(4), 453–458.

    Article  CAS  Google Scholar 

  89. Karagoz, H., et al. (2009). Comparison of efficacy of silicone gel, silicone gel sheeting, and topical onion extract including heparin and allantoin for the treatment of postburn hypertrophic scars. Burns, 35(8), 1097–1103.

    Article  PubMed  Google Scholar 

  90. Kim, J. W., Kim, Y. S., & Kyung, K. H. (2004). Inhibitory activity of essential oils of garlic and onion against bacteria and yeasts. Journal of Food Protection, 67(3), 499–504.

    Article  CAS  PubMed  Google Scholar 

  91. Koc, E., et al. (2008). An open, randomized, controlled, comparative study of the combined effect of intralesional triamcinolone acetonide and onion extract gel and intralesional triamcinolone acetonide alone in the treatment of hypertrophic scars and keloids. Dermatologic Surgery, 34(11), 1507–1514.

    CAS  PubMed  Google Scholar 

  92. Kook, S., Kim, G.-H., & Choi, K. (2009). The antidiabetic effect of onion and garlic in experimental diabetic rats: Meta-analysis. Journal of Medicinal Food, 12(3), 552–560.

    Article  CAS  PubMed  Google Scholar 

  93. Kumari, K., & Augusti, K. (2002). Antidiabetic and antioxidant effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa Linn) as compared to standard drugs in alloxan diabetic rats.

    Google Scholar 

  94. Kumari, K., & Augusti, K. (2007). Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats. Journal of Ethnopharmacology, 109(3), 367–371.

    Article  CAS  PubMed  Google Scholar 

  95. Yu, C. S., et al. (2010). Quercetin inhibited murine leukemia WEHI-3 cells in vivo and promoted immune response. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 24(2), 163–168.

    Article  CAS  Google Scholar 

  96. Zhou, Y., et al. (2011). Consumption of large amounts of Allium vegetables reduces risk for gastric cancer in a meta-analysis. Gastroenterology, 141(1), 80–89.

    Article  CAS  PubMed  Google Scholar 

  97. Zurada, J. M., Kriegel, D., & Davis, I. C. (2006). Topical treatments for hypertrophic scars. Journal of the American Academy of Dermatology, 55(6), 1024–1031.

    Article  PubMed  Google Scholar 

  98. Akash, M. S. H., Rehman, K., & Chen, S. (2014). Spice plant Allium cepa: Dietary supplement for treatment of type 2 diabetes mellitus. Nutrition, 30(10), 1128–1137.

    Article  CAS  PubMed  Google Scholar 

  99. Albanesi, M., et al. (2019). Immunological characterization of onion (Allium cepa) allergy. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 36(1), 98–103.

    Article  PubMed  PubMed Central  Google Scholar 

  100. Armentia, A., et al. (2020). Allergic hypersensitivity to garlic and onion in children and adults. Allergologia et Immunopathologia, 48(3), 232–236.

    Article  CAS  PubMed  Google Scholar 

  101. Brüll, V., et al. (2015). Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-) hypertension: A randomised double-blinded placebo-controlled cross-over trial. British Journal of Nutrition, 114(8), 1263–1277.

    Article  PubMed  Google Scholar 

  102. Burak, C., et al. (2017). Higher plasma quercetin levels following oral administration of an onion skin extract compared with pure quercetin dihydrate in humans. European Journal of Nutrition, 56, 343–353.

    Article  CAS  PubMed  Google Scholar 

  103. Campanati, A., et al. (2010). Effect of allium cepa-allantoin-pentaglycan gel on skin hypertrophic scars: Clinical and video-capillaroscopic results of an open-label, controlled, nonrandomized clinical trial. Dermatologic Surgery, 36(9), 1439–1444.

    Article  CAS  PubMed  Google Scholar 

  104. Choi, E.-Y., et al. (2015). Effect of onion peel extract on endothelial function and endothelial progenitor cells in overweight and obese individuals. Nutrition, 31(9), 1131–1135.

    Article  CAS  PubMed  Google Scholar 

  105. Conti, V., et al. (2020). Effectiveness and tolerability of a patch containing onion extract and allantoin for cesarean section scars. Frontiers in Pharmacology, 11, 569514.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  106. Draelos, Z. D., et al. (2010). Evaluation of an onion extract, Centella asiatica, and hyaluronic acid cream in the appearance of striae rubra. Skinmed, 8(2), 80–86.

    PubMed  Google Scholar 

  107. Ebrahimi-Mamaghani, M., et al. (2014). Effects of raw red onion consumption on metabolic features in overweight or obese women with polycystic ovary syndrome: A randomized controlled clinical trial. Journal of Obstetrics and Gynaecology Research, 40(4), 1067–1076.

    Article  CAS  PubMed  Google Scholar 

  108. Güngör, E. S., et al. (2020). The efficacy of onion extract in the management of subsequent abdominal hypertrophic scar formation. Journal of Wound Care, 29(10), 612–616.

    Article  PubMed  Google Scholar 

  109. Jenwitheesuk, K., et al. (2012). Role of silicone derivative plus onion extract gel in presternal hypertrophic scar protection: A prospective randomized, double blinded, controlled trial. International Wound Journal, 9(4), 397–402.

    Article  PubMed  Google Scholar 

  110. Jeong, S., et al. (2020). Effect of steamed onion (ONIRO) consumption on body fat and metabolic profiles in overweight subjects: A 12-week randomized, double-blind, placebo-controlled clinical trial. Journal of the American College of Nutrition, 39(3), 206–215.

    Article  CAS  PubMed  Google Scholar 

  111. Lee, J.-S., et al. (2016). Onion peel extract reduces the percentage of body fat in overweight and obese subjects: A 12-week, randomized, double-blind, placebo-controlled study. Nutrition Research and Practice, 10(2), 175–181.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  112. Nakayama, Y., et al. (2020). Effects of onion extract containing concentrated cysteine sulfoxides on sleep quality: A randomized, double-blind, placebo-controlled, crossover study. Food Science and Biotechnology, 29(12), 1755–1762.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  113. Nishimura, M., et al. (2019). Effect of daily ingestion of quercetin-rich onion powder for 12 weeks on visceral fat: A randomised, double-blind, placebo-controlled, parallel-group study. Nutrients, 12(1), 91.

    Article  PubMed  PubMed Central  Google Scholar 

  114. Wananukul, S., et al. (2013). A prospective placebo-controlled study on the efficacy of onion extract in silicone derivative gel for the prevention of hypertrophic scar and keloid in median sternotomy wound in pediatric patients. Journal of the Medical Association of Thailand, 96(11), 1428–1433.

    PubMed  Google Scholar 

  115. Yuan, X., et al. (2021). Onion extract gel is not better than other topical treatments in scar management: A meta-analysis from randomised controlled trails. International Wound Journal, 18(3), 396–409.

    Article  PubMed  Google Scholar 

  116. Zhang, J., et al. (2021). Association between dietary onion intake and subclinical hypothyroidism in adults: A population-based study from an iodine-replete area. Endocrine, 74, 616–624.

    Article  CAS  PubMed  Google Scholar 

  117. Zhou, X.-F., Ding, Z.-S., & Liu, N.-B. (2013). Allium vegetables and risk of prostate cancer: Evidence from 132,192 subjects. Asian Pacific Journal of Cancer Prevention, 14(7), 4131–4134.

    Article  PubMed  Google Scholar 

  118. Augusti, K. (1996). Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.). Indian Journal of Experimental Biology, 34(7), 634–640.

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Botany Department, Government College University, Faisalabad, Pakistan

    Sara Zafar, Nazia Aslam & Shagufta Perveen

  2. Botany, Department, Government College Women University, Faisalabad, Pakistan

    Abida Kausar

  3. Department of Pharmacy, Shaheed Benazir Bhutto University, Sheringal, Pakistan

    Muhammad Riaz

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  3. Abida Kausar
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  4. Shagufta Perveen
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  5. Muhammad Riaz
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Corresponding author

Correspondence to Sara Zafar .

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Editors and Affiliations

  1. Office of Research, Innovation and Commercialization, University of Engineering and Technology, Lahore, Pakistan

    Muhammad Zia-Ul-Haq

  2. Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia

    Arwa Abdulkreem AL-Huqail

  3. Department of Pharmacy, Shaheed Benazir Bhutto University, Sheringal Dir Upper, Pakistan

    Muhammad Riaz

  4. Institute of Industrial Biotechnology, Government College University, Lahore, Lahore, Pakistan

    Umar Farooq Gohar

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© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Zafar, S., Aslam, N., Kausar, A., Perveen, S., Riaz, M. (2023). Onion. In: Zia-Ul-Haq, M., Abdulkreem AL-Huqail, A., Riaz, M., Farooq Gohar, U. (eds) Essentials of Medicinal and Aromatic Crops. Springer, Cham. https://doi.org/10.1007/978-3-031-35403-8_17

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