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Urological Issues Related to Obstructive Sleep Apnea

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Obstructive Sleep Apnea

Abstract

Some urological conditions associated with OSAHS include erectile dysfunction, hormonal changes during puberty, irritative urinary tract symptoms, benign prostatic hyperplasia, neurogenic bladder, nocturia, lithiasis, and others. It can be defined that sexual dysfunction is the disturbance of any of the phases of human sexual response that causes dissatisfaction, damage to sexual health, and quality of life. Erectile dysfunction is defined as the persistent disability to achieving and maintaining an adequate erection that can let an unsatisfactory sexual performance. Almost 70% of erectile dysfunctions are caused by damage at this level.

There is a close relationship between OSAHS and urological diseases, either due to common pathophysiological processes or associated comorbidities, in some cases due to mechanisms not yet understood. Urinary tract symptoms alter sleep patterns, and treatment improves these patterns. There are increasing indications that patients with obstructive sleep apnea syndrome (OSAS) have a higher risk of increasing urinary symptoms, especially nocturia, as well as having a higher risk of benign prostatic hyperplasia, chronic prostatitis, urinary incontinence, lithiasis, prostate cancer, and renal failure.

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References

  1. Kang J, Keller J, et al. Association between obstructive sleep apnea and urinary calculi: a population-based case-control study. Urology. 2012;79(2):340–5.

    Article  PubMed  Google Scholar 

  2. Acuña A, Guerrero P, Aponte H. Lecciones de Sexología clínica. Editorial linotipia bolivar. Fundación universitaria de Ciencias de la Salud. 2007: 40–52.

    Google Scholar 

  3. Salonia A, Bettocchi C. et al. EUA guidelines on sexual and reproductive health. European Association of Urology 2022. http://www.uroweb.org/guideline/sexualandreproductivehealth/

  4. Konstantinovsky A, Tamir S, Katz G, et al. Erectile dysfunction, sleep disorders and endothelial function. IMAJ. 2019;21(6):408–11.

    PubMed  Google Scholar 

  5. Zhihao Y, Guodong DU, Lei MA, Yunhui LV, Yang Z, Tung On Y. Continuous positive airway pressure therapy in obstructive sleep apnoea patients with erectile dysfunction—A meta-analysis. Clin Respir J. 2020;15(163):168.

    Google Scholar 

  6. Mulhall JP, Trost LW, Brannigan RE, et al. Evaluation and management of testosterone deficiency: AUA guideline. J Urol. 2018;200:423. https://www.auanet.org/guidelines/guidelines/testosterone-deficiency-guideline

    Article  PubMed  Google Scholar 

  7. Burnett AL, Nehra A, Breau RH, et al. Disfunción eréctil: guía AUA. J Urol. 2018;200:633. https://www.auanet.org/guidelines/guidelines/erectile-dysfunction-(ed)-guideline

    Article  PubMed  Google Scholar 

  8. Coban S, Gunes A, Gul A, Turkoglu AR, Guzelsoy M, Ozturk M, Akyuz O, Kici O. Can continuous positive airway pressure improve lower urinary tract symptoms and erectile dysfunction in male patients with severe obstructive sleep apnea syndrome? Investig Clin Urol. 2020;61:607–12.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Zeyan L, Zhinquig F. The effect of CPAP and PDE5i on erectile function in men with obstructive sleep apnea and erectile dysfunction: a systematic review and meta-analysis. Sleep Med Rev. 2019;48:101217. https://doi.org/10.1016/j.smrv.2019.101217.

    Article  Google Scholar 

  10. Salk RH, Hyde JS, Abramson LY. Gender differences in depression in re- presentative national samples: meta-analyses of diagnoses and symptoms. Psychol Bull. 2017;143:783–822. https://doi.org/10.1037/bul0000102.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Johnson EO, Roth T, Schultz L, Breslau N. Epidemiology of DSM-IV insomnia in adolescence: lifetime prevalence, chronicity, and an emergent gender difference. Pediatrics. 2006;117:2. https://doi.org/10.1542/peds.2004-2629.

    Article  Google Scholar 

  12. Krishnan V, Collop NA. Gender differences in sleep disorders. Curr Opin Pulm Med. 2006;12:383–9.

    Article  PubMed  Google Scholar 

  13. Knutson KL. The association between pubertal status and sleep duration and quality among a nationally representative sample of US adolescents. Am J Hum Biol. 2005;17:418–24.

    Article  PubMed  Google Scholar 

  14. Westerterp-Plantenga MS. Conference on ‘roles of sleep and circadian rhythms in the origin and nutritional management of obesity and metabolic disease’ symposium 1: relevance of circadian rhythms and sleep to obesity and metabolic disease. Sleep, circadian rhythm and body weight: parallel developments. Proc Nutr Society. 2016;75:431–9.

    Article  CAS  Google Scholar 

  15. Chung S-D, et al. Obstructive sleep apnea and urological comorbidities in males: a population-based study. Sleep Breath. 2016;20(4):1203–8. https://doi.org/10.1007/s11325-016-1336-x.

    Article  PubMed  Google Scholar 

  16. Fantus R, Packiam V, et al. The relationship between sleep disorders and lower urinary tract symptoms: results from the NHANES. J Urol. 2018;200(1–6):161–6. https://doi.org/10.1016/j.juro.2018.01.083.

    Article  PubMed  Google Scholar 

  17. Helfand B, MacVary A, et al. The relationship between lower urinary tract symptom severity and sleep disturbance in the CAMUS trial. J Urol. 2011;185:2223–8. https://doi.org/10.1016/j.juro.2011.02.012.

    Article  PubMed  Google Scholar 

  18. Cakir O, MacVary K. LUTS and sleep disorders: emerging risk factor. Curr Urol Rep. 2012;13:407–12. https://doi.org/10.1007/s11934-012-0281-x.

    Article  PubMed  Google Scholar 

  19. Miyazaki T, Kolima S, et al. Nocturia in patients with sleep-disordered breathing and cardiovascular disease. Circ J. 2015;79:2632–40.

    Article  CAS  PubMed  Google Scholar 

  20. Alshahrani S, McGill J, Agarwal A. Prostatitis and male infertility. J Reprod Immunol. 2013;100(1):30–6. https://doi.org/10.1016/j.jri.2013.05.004.

    Article  PubMed  Google Scholar 

  21. Witthaus MW, Nipa F, Yang JH, Li Y, Lerner LB, Azadzoi KM. Bladder oxidative stress in sleep apnea contributes to detrusor instability and nocturia. J Urol. 2015;193(5):1692–9. https://doi.org/10.1016/j.juro.2014.11.055.

    Article  CAS  PubMed  Google Scholar 

  22. Abuyassim B, Sharman K, et al. Obstructive sleep apnea and kidney disease: a potential bidirectional relationship? J Clin Sleep Med. 2015;11(8):915–24.

    Article  Google Scholar 

  23. Lui T, Zhan Y, et al. Obstructive sleep apnea syndrome and risk of renal impairment: a systematic review and meta-analysis with trial sequential analysis. Sleep Breath. 2020;25:17–27. https://doi.org/10.1007/s11325-020-02090-5.

    Article  Google Scholar 

  24. Vilaseca A, Nguyeng D, et al. Obstructive sleep apnea and Fuhrman grade in patients with clear cell renal cell carcinoma treated surgically. World J Urol. 2016;35:51–6. https://doi.org/10.1007/s00345-016-1830-6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Varon, H.A.A., Vargas, D.C.N., Leal, D.M.C., Rodriguez, B.E.L.D.M. (2023). Urological Issues Related to Obstructive Sleep Apnea. In: Baptista, P.M., Lugo Saldaña, R., Amado, S. (eds) Obstructive Sleep Apnea. Springer, Cham. https://doi.org/10.1007/978-3-031-35225-6_16

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  • DOI: https://doi.org/10.1007/978-3-031-35225-6_16

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