Abstract
Obstructive sleep apnea (OSA) is a complex disease characterized by frequent complete (apnea) or partial (hypopnea) upper airway obstructed breathing. Whilst anatomical factors clearly play an important role in all patients, the degree to which anatomical versus non-anatomical causes contribute to OSA on an individual patient basis is highly variable. Airway collapse can occur at single or multiple sites along with the disturbance of neuromuscular, respiratory control, and arousal factors. Thus, patient phenotyping/endotyping techniques are needed to allow for the role of anatomical versus non-anatomical causal factors to be better understood within each individual patient.
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Carney, A.S., Catcheside, P.G., Eckert, D.J. (2023). OSA Pathogenesis. In: Delakorda, M., de Vries, N. (eds) The Role of Epiglottis in Obstructive Sleep Apnea. Springer, Cham. https://doi.org/10.1007/978-3-031-34992-8_2
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DOI: https://doi.org/10.1007/978-3-031-34992-8_2
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