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External Beam Radiotherapy for Nose Vestibule Malignancies

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Malignancies of the Nasal Vestibule

Abstract

Nose vestibule malignancies are rare, and randomized/prospective studies on available treatments are not available. External beam radiotherapy (EBRT), among other treatment options, has an acknowledged role as primary treatment, especially for small lesions, and in the postoperative setting, both alone and in combination with brachytherapy and chemotherapy. Nowadays, modern techniques that include IMRT and volumetric-modulated radiation therapy (VMAT) are routinely used in most centers. Target volumes are highly dependent on tumor characteristics and, in our opinion, the predictable spread patterns. The acute morbidity with EBRT is usually mild and well tolerated while late toxicities are rarely reported. Cosmetic results after EBRT are usually good, while the impact on smell function and mucociliary function can seriously impact the quality of life.

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Author information

Authors and Affiliations

  1. Radiation Oncology, Ospedale del Mare, ASL Napoli 1 Centro, Naples, Italy

    Ida D’Onofrio

  2. Otolaryngology, Mater Olbia Hospital, Olbia, Italy

    Roberto Gallus

  3. Institute of Radiological Sciences, Azienda Ospedaliero Universitaria, Sassari, Italy

    Fabrizio Sanna & Dalila Di Mario

  4. Otolaryngology Division, Azienda Ospedaliero Universitaria, Sassari, Italy

    Emilia Degni

  5. Radioterapia Oncologica, Ospedale “San Francesco”, Nuoro, Italy

    Salvatrice Campoccia

  6. UOC Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy

    Luca Tagliaferri

  7. Department of Oncology-Radiotherapy, Gustave Roussy, Villejuif, France

    Yun Gan Tao

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  1. Ida D’Onofrio
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  2. Roberto Gallus
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Corresponding author

Correspondence to Roberto Gallus .

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Editors and Affiliations

  1. Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy

    Francesco Bussu

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D’Onofrio, I. et al. (2023). External Beam Radiotherapy for Nose Vestibule Malignancies. In: Bussu, F. (eds) Malignancies of the Nasal Vestibule. Springer, Cham. https://doi.org/10.1007/978-3-031-32850-3_10

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  • DOI: https://doi.org/10.1007/978-3-031-32850-3_10

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