Abstract
Aortic diseases encompass a wide of range of pathologies, which can involve heart chambers and valves and can extend to vascular branches, besides affecting the aortic wall. Cardiac magnetic resonance (CMR) has emerged as a multiparametric diagnostic tool which allows the assessment of complex disease within a single examination. Vessel course, patency, and connections, together with vessel wall, plaque characteristics, intimal flaps, and intramural haemorrhage can be visualized thanks to specific functional (SSFP cines, fast gradient echo and velocity encoding sequences) and morphologic sequences (fast spin echo sequences). Aortic wall inflammation can be assessed with STIR T2-weighted images and late gadolinium enhancement. Contrast-enhanced magnetic resonance angiography (CE-MRA) allows the acquisition of isotropic 3D datasets with high space resolution that can be reconstructed in any plane and is the ideal tool to assess aortic anatomy and dimensions and characterize pathology like aneurysms, dissection, atherosclerotic plaque, and thrombus, while assessing the presence or extension of pathology to main aortic branches. Moreover, in the same examination cardiac chambers dimensions, function and heart muscle tissue characterization can be achieved, together with detailed morphologic and functional evaluation of heart valves. In this chapter, an introduction to the applications of CMR in the study of aortic disease is presented and is followed by the description of ten clinical cases. These cases highlight the role of CMR and CE-MRA in the diagnostic workflow of aortic pathology, as well as in decision-making process and disease follow-up. Moreover, the cases emphasize the relevance of an integrated advanced cardiac imaging approach in the management of aortic pathology and the key role of knowledge of patients’ global clinical frame in aortic disease, as the aorta can be a target of systemic connective or rheumatologic pathology.
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Acknowledgments
Dr. Patrizia Pedrotti and Dr. Giuseppina Quattrocchi are grateful to Dr. Selene Capitanio and to Dr. Antonio Gaetano Rampoldi, respectively, affiliated to Nuclear Medicine and Interventional Radiology Units of ASST Grande Ospedale Metropolitano Niguarda of Milano, Italy, for providing 18F-FDG PET-CT and angiographic images related to clinical cases 5, 6 and 7.
Dr. Patrizia Pedrotti is particularly grateful to Dr. Andrea Barison for his assistance in drafting this chapter.
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Short-axis bSSFP cine view (same as Fig. 16.3, upper panel) (MP4 6048 kb)
Paracoronal bSSFP cine view (same as Fig. 16.3, lower panel) (MP4 4711 kb)
Type A aortic dissection: bSSFP parasagittal stack. bSSFP sequence (MP4 6233 kb)
Type A aortic dissection: bSSFP paracoronal stack. bSSFP sequence (MP4 1672 kb)
Type A aortic dissection on CT scan, axial stack (MP4 1990 kb)
Type B aortic dissection: parasagittal cine view. bSSFP sequence (MP4 5101 kb)
Type B aortic dissection: 3D volume rendering. CE-MRA sequence (MP4 639 kb)
Pseudoaneurysm of the descending aorta: bSSFP sequence. Parasagittal cine view (MP4 8283 kb)
Pseudoaneurysm of the descending aorta: CE-MRA sequence. Parasagittal cine view (MP4 4881 kb)
Follow-up CT scan after pseudoaneurysm exclusion (MP4 3118 kb)
Parasagittal SSFP cine image of the aorta (MP4 222 kb)
SSFP cine of the aorta, parasagittal view (MP4 269 kb)
SSFP cine of left ventricular outflow tract, coronal plane (MP4 82 kb)
CE-MRA 3-D reconstruction (MP4 93 kb)
SSFP cine, RVOT view (MP4 213 kb)
SSFP cine, in-out right ventricle view (MP4 333 kb)
SSFP cine, pulmonary valve plane (MP4 128 kb)
Through-plane velocity-encoded images of the pulmonary valve (MP4 269 kb)
CE-MRA 3-D reconstruction (MP4 213 kb)
Aneurysm of thoracic descending and abdominal aorta: 3D volume rendering from CE-MRA sequence (MOV 285 kb)
Aneurysm of thoracic descending and abdominal aorta: parasagittal bSSFP cine view (MOV 4485 kb)
Bicuspid aortic valve with fused coronary cusps. Axial view bSSFP cine image (MP4 87 kb)
Aneurysm of ascending aorta. 3D volume rendering from CE-MRA sequence (MOV 177 kb)
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Aimo, A., La Mura, L., Quattrocchi, G., Pedrotti, P. (2023). Aortic Diseases. In: Barison, A., Dellegrottaglie, S., Pontone, G., Indolfi, C. (eds) Case-based Atlas of Cardiovascular Magnetic Resonance. Springer, Cham. https://doi.org/10.1007/978-3-031-32593-9_16
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DOI: https://doi.org/10.1007/978-3-031-32593-9_16
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