Abstract
Sleep is accompanied by several physiological changes relevant to ventilation and respiration. During sleep, variations in airway resistance, muscle contractility, and central respiratory control occurs, which can compromise ventilation.
Sleep breathing disorders (SBDs) are relatively common and have a significant health implications.
SBD is a group of disorders which includes obstructive sleep apnea (OSA), central sleep apnea (CSA), and obesity hypoventilation syndrome (OHS).
Polysomnography (PSG) must be performed in all suspected patients, because it is the gold standard for the diagnosis of this kind of disorders.
Treatment of these conditions must contemplate pharmacological and non-pharmacological measures; noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) may play an important role in the management and treatment of this kind of disorders.
SBD is associated with high morbidity and mortality, so early diagnosis is essential for appropriate treatment to improve the prognosis and quality of life of patients.
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References
Weitzenblum E, Chaouat A. Sleep and chronic obstructive pulmonary disease. Sleep Med Rev. 2004;8:281.
Dempsey JA, Veasey SC, Morgan BJ, O'Donnell CP. Pathophysiology of sleep apnea. Physiol Rev. 2010;90:47.
Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnoea: a population health perspective. Am J Respir Crit Care Med. 2002;165:1217–39.
American Academy of Sleep Medicine. International classification of sleep disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.
Cathain EO, Gaffey MM. Upper airway obstruction. In: StatPearls. Treasure Island, FL: StatPearls Publishing; 2022. https://www.ncbi.nlm.nih.gov/books/NBK564399/.
Kubin L. Neural control of the upper airway: respiratory and state-dependent mechanisms. Compr Physiol. 2016;6(4):1801–50. https://doi.org/10.1002/cphy.c160002. PMID: 27783860; PMCID: PMC5242202.
Skatrud JB, Dempsey JA. Interaction of sleep state and chemical stimuli in sustaining rhythmic ventilation. J Appl Physiol Respir Environ Exerc Physiol. 1983;55:813.
Tangel DJ, Mezzanotte WS, White DP. Influence of sleep on tensor palatini EMG and upper airway resistance in normal men. J Appl Physiol. 1985;1991(70):2574.
Tangel DJ, Mezzanotte WS, Sandberg EJ, White DP. Influences of NREM sleep on the activity of tonic vs. inspiratory phasic muscles in normal men. J Appl Physiol. 1985;1992(73):1058.
Lee W, Nagubadi S, Kryger MH, Mokhlesi B. Epidemiology of obstructive sleep apnea: a population-based perspective. Expert Rev Respir Med. 2008;2(3):349–64. https://doi.org/10.1586/17476348.2.3.34932.
Punjabi NM. The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):136–43. https://doi.org/10.1513/pats.200709-155MG33.
Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013;177(9):1006–14. https://doi.org/10.1093/aje/kws34234.
Franklin KA, Lindberg E. Obstructive sleep apnea is a common disorder in the population-a review on the epidemiology of sleep apnea. J Thorac Dis. 2015;7(8):1311–22. https://doi.org/10.3978/j.issn.2072-1439.2015.06.11.
Senaratna CV, English DR, Currier D, et al. Sleep apnoea in Australian men: disease burden, co-morbidities, and correlates from the Australian longitudinal study on male health. BMC Public Health. 2016;16(Suppl 3):1029. https://doi.org/10.1186/s12889-016-3703-8.
Hendricks JC, Kovalski RJ, Kline LR. Phasic respiratory muscle patterns and sleep-disordered breathing during rapid eye movement sleep in the English bulldog. Am Rev Respir Dis. 1991;144(5):1112–20. https://doi.org/10.1164/ajrccm/144.5.111.
Brennan LC, Kirkham FJ, Gavlak JC. Sleep-disordered breathing and comorbidities: role of the upper airway and craniofacial skeleton. Nat Sci Sleep. 2020;12:907–36. https://doi.org/10.2147/NSS.S146608. PMID: 33204196; PMCID: PMC7667585.
Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea–hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005;365:1046–53. 326AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE VOL 179 2009.
Young T, Palta M, et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328:1230.
Young T, Evans L, et al. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women. Sleep. 1997;20:705–6.
Bixler EO, Vgontzas AN, Lin HM, et al. Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med. 2001;163:608.
Jordan AS, McSharry DG, Malhotra A. Adult obstructive sleep apnoea. Lancet. 2014;383:736.
Arita A, Kumagai H, Sawatari H, Hoshino T, Konishi N, Murase Y, Urabe A, Nomura A, Sasanabe R, Shiomi T. Advanced emergency braking system reduces the risk of motor vehicle collisions caused by falling asleep while driving in patients with untreated obstructive sleep apnea. J Sleep Res. 2022;32:e13713. https://doi.org/10.1111/jsr.13713. Epub ahead of print.
Reeves-Hoche MK, Hudgel DW, Meck R, Witteman R, Ross A, Zwillich CW. Continuous versus bilevel positive airway pressure for obstructive sleep apnea. Am J Respir Crit Care Med. 1995;151:443–9. [PubMed: 7842204].
Vennelle M, White S, Riha RL, Mackay TW, Engleman HM, Douglas NJ. Randomized controlled trial of variable-pressure versus fixed-pressure continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnea/hypopnea syndrome (OSAHS). Sleep. 2010;33:267–71. [PubMed: 20175411]
Kent D, Stanley J, Aurora RN, et al. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021;17:2499.
Eijsvogel MM, Ubbink R, Dekker J, et al. Sleep position trainer versus tennis ball technique in positional obstructive sleep apnea syndrome. J Clin Sleep Med. 2015;11:139.
Stepanski EJ, Wyatt JK. Use of sleep hygiene in the treatment of insomnia. Sleep Med Rev. 2003;7:215.
Qaseem A, Holty JE, Owens DK, et al. Management of obstructive sleep apnea in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2013;159:471.
Donovan LM, Kapur VK. Prevalence and characteristics of central compared to obstructive sleep apnea: analyses from the sleep heart health study cohort. Sleep. 2016;39(7):1353–9. https://doi.org/10.5665/sleep.5962. PMID: 27166235; PMCID: PMC4909617.
Guilleminault C, van den Hoed J, Mitler MM. Clinical overview of the sleep apnea syndromes. In: Guilleminault C, Dement W, editors. Sleep apnea syndromes. New York: Alan R Liss; 1978. p. 1–12.
Mokhlesi B, Masa JF, Brozek JL, et al. Evaluation and management of obesity hypoventilation syndrome. An official American Thoracic Society clinical practice guideline. Am J Respir Crit Care Med. 2019;200:e6.
Sanders MH, Newman AB, Haggerty CL, et al. Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway disease. Am J Respir Crit Care Med. 2003;167:7.
Jacobs SS, Lederer DJ, Garvey CM, et al. Optimizing home oxygen therapy. An official American Thoracic Society workshop report. Ann Am Thorac Soc. 2018;15(12):1369–81.
Department of Health and Human Services. Centers for medicare and medicaid services. Home oxygen therapy. 2015.
Dunn WF, Nelson SB, Hubmayr RD. Oxygen-induced hypercarbia in obstructive pulmonary disease. Am Rev Respir Dis. 1991;144:526.
Spiesshoefer J, Bannwitz B, Mohr M, Herkenrath S, Randerath W, Sciarrone P, Thiedemann C, Schneider H, Braun AT, Emdin M, Passino C, Dreher M, Boentert M, Giannoni A. Effects of nasal high flow on sympathovagal balance, sleep, and sleep-related breathing in patients with precapillary pulmonary hypertension. Sleep Breath. 2021;25(2):705–17. https://doi.org/10.1007/s11325-020-02159-1. Epub 2020 Aug 22. PMID: 32827122; PMCID: PMC8195975.
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Silva, J., Portela, J. (2023). Sleep Breathing Disorders in Upper Airway Disorders Implications for Noninvasive Ventilation. In: Esquinas, A.M., De Vito, A., Barbetakis, N. (eds) Upper Airway Disorders and Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-031-32487-1_37
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DOI: https://doi.org/10.1007/978-3-031-32487-1_37
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