Abstract
Variations (formerly “disorders”) of sex development (DSD) describe congenital conditions with atypical constellations between the chromosomal, the gonadal, and the phenotypic sex. This definition encompasses a variety of clinical entities and is not strictly defined regarding its inclusive- and exclusiveness, because the classification allows for both a clinical and a (molecular-) genetic nomenclature and classification. In addition, the DSD complex is associated with a concept of clinical care and medical management, as affected persons may have a very special gender self-perception, which may impose a sociocultural challenge. In the following chapter, we therefore introduce the present classification and the current discussion about medical management before we explain defined conditions.
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Notes
- 1.
For reasons of better readability, the masculine form is used for personal names and personal nouns in this chapter. Corresponding terms apply in principle to all genders for the purpose of equal treatment.
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Wagner, I.V., Hiort, O. (2023). Variants of Sex Development. In: Nieschlag, E., Behre, H.M., Kliesch, S., Nieschlag, S. (eds) Andrology. Springer, Cham. https://doi.org/10.1007/978-3-031-31574-9_31
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