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Heart of the Matter

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Transfusion Medicine

Abstract

A large cardiac surgery center is planning an audit of blood product usage and wastage. Basics of audit planning are outlined. Emphasis is placed on platelets and plasma usage in conjunction with the use of cardiopulmonary bypass. Monitoring of hemostatic parameters in theaters is greatly facilitated by the adoption of viscoelastic clot tests. Causes of intra- and postoperative bleeding, including heparin overdose and platelet dysfunction, are discussed, as well as the timing of antiplatelet drug discontinuation. Despite red cell anatomical and biochemical changes during storage, age of transfused red cells does not seem to influence the mortality rates and organ dysfunction scores.

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References

  1. Steiner ME, Ness PM, Assmann SF, et al. Effects of red-cell storage duration on patients undergoing cardiac surgery. New Engl J Med. 2015;372:1419–29.

    Article  CAS  PubMed  Google Scholar 

  2. Welsby IJ, Lockhart E, Phillips-Bute B, et al. Storage age of transfused platelets and outcomes after cardiac surgery. Transfusion. 2010;50:2311–7.

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  3. Weightman WM, Gibbs NM, Weidmann CR, et al. The effect of aspirin-free interval on red blood cell transfusion requirements in cardiac surgical patients. J Cardiothorac Vasc Anesth. 2002;16:54–8.

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  4. NICE guideline on antiplatelet treatment, revision; 2020.

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Further Reading

  1. Van den Watering L. Red cell storage and prognosis. Vox Sang. 2011;100:36–45.

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  2. McCullough J. Transfusion medicine. 5th ed. Wiley Blackwell; 2021.

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Correspondence to Aleksandar Mijovic .

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© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Mijovic, A. (2023). Heart of the Matter. In: Mijovic, A. (eds) Transfusion Medicine. Springer, Cham. https://doi.org/10.1007/978-3-031-31462-9_21

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  • DOI: https://doi.org/10.1007/978-3-031-31462-9_21

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-31461-2

  • Online ISBN: 978-3-031-31462-9

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