Abstract
A large cardiac surgery center is planning an audit of blood product usage and wastage. Basics of audit planning are outlined. Emphasis is placed on platelets and plasma usage in conjunction with the use of cardiopulmonary bypass. Monitoring of hemostatic parameters in theaters is greatly facilitated by the adoption of viscoelastic clot tests. Causes of intra- and postoperative bleeding, including heparin overdose and platelet dysfunction, are discussed, as well as the timing of antiplatelet drug discontinuation. Despite red cell anatomical and biochemical changes during storage, age of transfused red cells does not seem to influence the mortality rates and organ dysfunction scores.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Steiner ME, Ness PM, Assmann SF, et al. Effects of red-cell storage duration on patients undergoing cardiac surgery. New Engl J Med. 2015;372:1419–29.
Welsby IJ, Lockhart E, Phillips-Bute B, et al. Storage age of transfused platelets and outcomes after cardiac surgery. Transfusion. 2010;50:2311–7.
Weightman WM, Gibbs NM, Weidmann CR, et al. The effect of aspirin-free interval on red blood cell transfusion requirements in cardiac surgical patients. J Cardiothorac Vasc Anesth. 2002;16:54–8.
NICE guideline on antiplatelet treatment, revision; 2020.
Further Reading
Van den Watering L. Red cell storage and prognosis. Vox Sang. 2011;100:36–45.
McCullough J. Transfusion medicine. 5th ed. Wiley Blackwell; 2021.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Mijovic, A. (2023). Heart of the Matter. In: Mijovic, A. (eds) Transfusion Medicine. Springer, Cham. https://doi.org/10.1007/978-3-031-31462-9_21
Download citation
DOI: https://doi.org/10.1007/978-3-031-31462-9_21
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-31461-2
Online ISBN: 978-3-031-31462-9
eBook Packages: MedicineMedicine (R0)