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Upper Gastrointestinal Bleeding

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Acute Care Surgery in Geriatric Patients
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Abstract

Classically, gastrointestinal bleeding is separated into upper gastrointestinal bleeding (UGIB) or lower gastrointestinal bleeding (LGIB). Bleeding can be classified as acute or chronic, with acute bleeds more sudden and apparent and chronic bleeds more insidious. Upper GI bleeding is considered bleeding originating above the Ligament of Treitz. Acute Upper GI bleeding usually presents as hematemesis, coffee ground emesis, or melena. However, chronic UGIB can manifest with fatigue, weakness, or syncopal episodes as a sequela to blood loss. Upper GI bleeding has a more common occurrence than lower GI bleeds. With gastrointestinal bleeding a common problem seen in the elderly, adhering to an accurate diagnostic and treatment algorithm is crucial in managing upper GI bleeds.

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References

  1. van Leerdam ME. Epidemiology of acute upper gastrointestinal bleeding. Best Pract Res Clin Gastroenterol. 2008;22(2):209–24. https://doi.org/10.1016/j.bpg.2007.10.011.

    Article  PubMed  Google Scholar 

  2. Narayanan M, Reddy KM, Marsicano E. Peptic ulcer disease and Helicobacter pylori infection. Mo Med. 2018;115(3):219–24.

    PubMed  PubMed Central  Google Scholar 

  3. Malik TF, Gnanapandithan K, Singh K. Peptic ulcer disease. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. https://www.ncbi.nlm.nih.gov/books/NBK534792/.

    Google Scholar 

  4. Huang JQ, Sridhar S, Hunt RH. Role of helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis. Lancet. 2002;359(9300):14–22.

    Article  CAS  PubMed  Google Scholar 

  5. Meseeha M, Attia M. Esophageal varices. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. https://www.ncbi.nlm.nih.gov/books/NBK448078/.

    Google Scholar 

  6. Nejat Pish-Kenari F, Qujeq D, Maghsoudi H. Some of the effective factors in the pathogenesis of gastro-oesophageal reflux disease. J Cell Mol Med. 2018;22(12):6401–4.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Harris JM, DiPalma JA. Clinical significance of Mallory-Weiss tears. Am J Gastroenterol. 1993;88(12):2056.

    CAS  PubMed  Google Scholar 

  8. Velmurugan B, Mani A, Nagini S. Combination of S-allylcysteine and lycopene induces apoptosis by modulating Bcl-2, Bax, Bim and caspases during experimental gastric carcinogenesis. Eur J Cancer Prev. 2005;14:387–93.

    Article  CAS  PubMed  Google Scholar 

  9. Mitacek EJ, Brunnemann KD, Suttajit M, Caplan LS, Gagna CE, Bhothisuwan K, Siriamornpun S, Hummel CF, Ohshima H, Roy R, et al. Geographic distribution of liver and stomach cancers in Thailand in relation to estimated dietary intake of nitrate, nitrite, and nitrosodimethylamine. Nutr Cancer. 2008;60:196–203.

    Article  PubMed  Google Scholar 

  10. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69–90.

    Article  PubMed  Google Scholar 

  11. Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol. 2006;12:354–62.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Baradarian R, Ramdhaney S, Chapalamadugu R, et al. Early intensive resuscitation of patients with upper gastrointestinal bleeding decreases mortality. Am J Gastroenterol. 2004;99:619–22.

    Article  PubMed  Google Scholar 

  13. Serafini M, Jakszyn P, Luján-Barroso L, Agudo A, Bas Bueno-de-Mesquita H, van Duijnhoven FJ, Jenab M, Navarro C, Palli D, Boeing H, et al. Dietary total antioxidant capacity and gastric cancer risk in the European prospective investigation into cancer and nutrition study. Int J Cancer. 2012;131:e544–54.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Jun L. Levine .

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Levine, J.L. (2023). Upper Gastrointestinal Bleeding. In: Petrone, P., Brathwaite, C.E. (eds) Acute Care Surgery in Geriatric Patients. Springer, Cham. https://doi.org/10.1007/978-3-031-30651-8_46

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  • DOI: https://doi.org/10.1007/978-3-031-30651-8_46

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-30650-1

  • Online ISBN: 978-3-031-30651-8

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