Abstract
The prototypic enzymatic reactions introduced in Chap. 7 are shown in this chapter as they combine and function coordinately as “metabolic modules.” Metabolic modules are short enzymatic reaction sequences connected by common intermediates. Metabolic modules frequently reoccur in many different pathways and combine to form new pathways. Metabolic modules reveal the logic of metabolic pathways and their evolution, and, thus, provide a useful factual and intuitive understanding of metabolism.
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Further Readings
Lehninger AL (1982) Principles of biochemistry. Worth Publishers
Ahmed H, Ettema TJG, Tjaden B, Geerling ACM, van der Oost J, Siebers B (2005) The semi-phosphorylative Entner–Doudoroff pathway in hyperthermophilic archaea: a re-evaluation. Biochem J 390(2):529–540
Siebers B, Schoenheit P (2005) Unusual pathways and enzymes of central carbohydrate metabolism in Archaea. Curr Opin Microbiol 8:695–706
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Spormann, A.M. (2023). Metabolic Modules, Pathways, and Nodes of Intermediates. In: Principles of Microbial Metabolism and Metabolic Ecology. Springer, Cham. https://doi.org/10.1007/978-3-031-28218-8_8
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DOI: https://doi.org/10.1007/978-3-031-28218-8_8
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