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Time Series Analysis of Asthma Hospital Admissions and Air Quality in Sofia – A Pilot Study

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Environmental Protection and Disaster Risks (EnviroRISKs 2022)

Abstract

Asthma is a multifaceted inflammatory disease of the airways, which takes a heavy toll on public health and quality of life in Bulgaria. The present study aimed to investigate the short-term effects of air pollution on hospital admission for asthma in the city of Sofia.

Daily admission counts and air pollutant concentrations (PM2.5, PM10, NO2, SO2, CO, and O3) were obtained for Sofia in the period January 1, 2009 to December 31, 2018. Their associations were analyzed using negative binomial regressions with air pollution lagged over 0–7 days.

In the child population, at some lags, 10 µg/m3 increase in NO2 increased the risk of hospital admission by up to 6%, SO2 by 13%, and PM2.5 by 3%. Results for O3 were conflicting, even though at some lags the risk reached 5% per 10 µg/m3. At lag0, CO increased the risk of hospitalization in the group 0–4 years by 7.4%, which reached an IRR of 2.53 (95% CI: 1.27, 5.07) in the distributed lag models. It was estimated that approximately 6% of the admissions in children (5–14 years old) could be attributable to short-term PM2.5 ≥ 15 µg/m3 and NO2 ≥ 25 µg/m3.

Overall, short-term increases in some air pollutants in Sofia increased the risk of hospital admissions, more clearly among asthmatic children, over the following week. A small but non-trivial proportion of admissions in 5–14 years old children was attributable to air pollution.

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Acknowledgements

This work has been carried out in the framework of the National Science Program “Environmental Protection and Reduction of Risks of Adverse Events and Natural Disasters”, approved by the Resolution of the Council of Ministers №577/17.08.2018 and supported by the Ministry of Education and Science (MES) of Bulgaria (Agreement № Д01-279/03.12.2021).

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Correspondence to Angel M. Dzhambov .

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Dzhambov, A.M., Dikova, K., Georgieva, T., Mukhtarov, P., Dimitrova, R. (2023). Time Series Analysis of Asthma Hospital Admissions and Air Quality in Sofia – A Pilot Study. In: Dobrinkova, N., Nikolov, O. (eds) Environmental Protection and Disaster Risks. EnviroRISKs 2022. Lecture Notes in Networks and Systems, vol 638. Springer, Cham. https://doi.org/10.1007/978-3-031-26754-3_17

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  • DOI: https://doi.org/10.1007/978-3-031-26754-3_17

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