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Retrospective and Differential Pathogen Diagnosis

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Interdisciplinary Insights from the Plague of Cyprian

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Abstract

This chapter focuses on the key and difficult issue of retrospective pathogen diagnosis in regard to the Plague of Cyprian. Having eliminated a wide range of pathogenic suspects in Part I (including a number of VHFs), we analytically turn our attention to considering the filoviruses. Most of these are differentially eliminated quickly through our systems-synthesis methodology. A far more detailed examination of the Ebola virus (EBOV) and Marburg virus (MARV) evolutionary lineages produces the conclusion that the MARV evolutionary lineage, from a wide variety of analytical interdisciplinary perspectives, is by far the more likely to have been the probable pathogenic cause of the Plague of Cyprian.

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Author information

Authors and Affiliations

  1. Department of History, Doane University, Crete, NE, USA

    Mark Orsag

  2. Institute for Human and Planetary Health, Crete, NE, USA

    Amanda E. McKinney

  3. Bucknell University, Lewisburg, PA, USA

    DeeAnn M. Reeder

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  1. Mark Orsag
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  2. Amanda E. McKinney
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  3. DeeAnn M. Reeder
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Correspondence to Mark Orsag .

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Orsag, M., McKinney, A.E., Reeder, D.M. (2023). Retrospective and Differential Pathogen Diagnosis. In: Interdisciplinary Insights from the Plague of Cyprian. Palgrave Macmillan, Cham. https://doi.org/10.1007/978-3-031-26094-0_4

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  • DOI: https://doi.org/10.1007/978-3-031-26094-0_4

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  • Publisher Name: Palgrave Macmillan, Cham

  • Print ISBN: 978-3-031-26093-3

  • Online ISBN: 978-3-031-26094-0

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