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Transmyocardial Laser Revascularization

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Ischemic Heart Disease
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Abstract

It has been almost a decade since transmyocardial laser revascularization (TMR) was approved for clinical use. The safety of TMR was demonstrated initially with non-randomized studies in which TMR was used as the only treatment for patients with severe angina. TMR efficacy was proven after multiple randomized controlled trials. These revealed significant angina relief compared to maximum medical therapy in patients with diffuse coronary disease not amenable to conventional revascularization. In light of these results, TMR has been used as an adjunct to coronary artery bypass grafting (CABG). Even though TMR has to be implemented and tested to increase the therapeutic cohort, it represents a valid option as sole therapy and in combination with CABG. Further experiments will be carried out in association with other innovative newborn treatment.

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Abbreviations

BMLR:

Bone marrow laser revascularization

CABG:

Coronary artery bypass grafting

CAD:

Coronary artery disease

LIMA:

Left internal mammary artery

PCI:

Percutaneous coronary intervention

TEE:

Transesophageal echocardiography

TMR:

Transmyocardial laser revascularization

VEGF:

Vascular endothelial growth factor

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Zancanaro, E. (2023). Transmyocardial Laser Revascularization. In: Concistrè, G. (eds) Ischemic Heart Disease. Springer, Cham. https://doi.org/10.1007/978-3-031-25879-4_33

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  • DOI: https://doi.org/10.1007/978-3-031-25879-4_33

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-25878-7

  • Online ISBN: 978-3-031-25879-4

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