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Peripheral Arterial Disease and Diabetes Mellitus

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Abstract

Peripheral arterial disease (PAD) is the partial or total occlusion of peripheral arteries and is usually due to atherosclerotic disease. While it can be diagnosed in a variety of ways, it is objectively most commonly defined as an ankle brachial index <0.9. It results in a spectrum of manifestations ranging from asymptomatic disease, intermittent claudication, rest pain, and tissue loss to gangrene. Furthermore, the presence of PAD is a coronary artery disease equivalent and puts patients at risk for cardiovascular and cerebrovascular complications and mortality. Diabetes is a primary risk factor for PAD. The severity and progression of PAD are accelerated when associated with diabetes. Patients with diabetes are among those most vulnerable to developing PAD, and they suffer the most complications and worst outcomes, making early detection and risk factor modification paramount in their treatment.

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Authors and Affiliations

  1. Division of Vascular and Endovascular Surgery, Department of Surgery, Long School of Medicine, University of Texas Health San Antonio, San Antonio, TX, USA

    Georges M. Haidar & Boulos Toursarkissian

  2. Peripheral Vascular Associates, San Antonio, TX, USA

    Georges M. Haidar & Boulos Toursarkissian

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  1. Georges M. Haidar
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  2. Boulos Toursarkissian
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Correspondence to Boulos Toursarkissian .

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  1. Mexico City, Mexico

    Joel Rodriguez-Saldana

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Haidar, G.M., Toursarkissian, B. (2023). Peripheral Arterial Disease and Diabetes Mellitus. In: Rodriguez-Saldana, J. (eds) The Diabetes Textbook. Springer, Cham. https://doi.org/10.1007/978-3-031-25519-9_52

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