Abstract
Schwannoma is a benign neoplasm of Schwann cells. It can occur in the head and neck region and is most commonly found on the tongue intraorally. Schwannoma presents as an asymptomatic, slow-growing solitary lump. Occasionally, patients may also report pain and paraesthesia. Histologically, a schwannoma shows an encapsulated tumour with the characteristic ‘Antoni A’ and ‘Antoni B’ patterns. ‘Antoni A’ shows a hypercellular area of palisaded spindle cells with elongated nuclei. The acellular eosinophilic area in between the palisaded nuclei is termed the Verocay body. ‘Antoni B’ area is hypocellular and the cells are arranged in a more disorganized pattern. The treatment for this lesion is surgical excision and recurrence is unlikely.
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Further Reading
Colreavy MP, Lacy PD, Hughes J, et al. Head and neck schwannomas–a 10 year review. J Laryngol Otol. 2000;114(02):119–24.
Cohen M, Wang MB. Schwannoma of the tongue: two case reports and review of the literature. Eur Arch Otorhinolaryngol. 2009;266(11):1823–9. https://doi.org/10.1007/s00405-008-0907-2.
Dokania V, Rajguru A, Mayashankar V, Mukherjee I, Jaipuria B, Shere D. Palatal schwannoma: an analysis of 45 literature reports and of an illustrative case. Int Arch Otorhinolaryngol. 2019;23(3):e360–70.
Fine SW, McClain SA, Li M. Immunohistochemical staining for calretinin is useful for differentiating schwannomas from neurofibromas. Am J Clin Pathol. 2004;122(4):552–9. https://doi.org/10.1309/AGBG-TBRJ-4W0B-C7LN. PMID: 15487453
López-Carriches C, Baca-Pérez-Bryan R, Montalvo-Montero S. Schwannoma located in the palate: clinical case and literature review. Med Oral Patol Oral Cir Bucal. 2009;14(09):e465–8.
Lopez-Jornet P, Bermejo Fenoll-Ambrosio. Neurilemmoma of the tongue. Oral Oncol Extra 2005; 41:154-157.
Santos PPA, Freitas VS, Pinto LP, Freitas RA, de Souza LB. Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature. Ann Diagn Pathol. 2010;14(4):235–9.
Woo SB. Oral pathology E-book: a comprehensive atlas and text. Elsevier Health Sciences; 2016.
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Zainuddin, N.I. (2023). Lump on the Tongue: Schwannoma. In: Tilakaratne, W.M., Kallarakkal, T.G. (eds) Clinicopathological Correlation of Oral Diseases. Springer, Cham. https://doi.org/10.1007/978-3-031-24408-7_20
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DOI: https://doi.org/10.1007/978-3-031-24408-7_20
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