Abstract
Vascular anomalies can be regarded as lesions arising from congenital errors in angiogenesis and are relatively common in the head and neck region. They usually present as bluish-purple soft and compressible lesions and tend to bleed profusely if traumatised. The classification and nomenclature for vascular anomalies are complex and encompass a diverse range of lesions of different origins, locations and pathogenesis. While a working diagnosis can be made based on history and clinical findings for most lesions, a histopathological examination may be required in some of the clinical appearances that are less conclusive. Any surgical interventions for diagnosis or treatment have to be performed with extreme care and appropriate measures to manage potential profuse intra-operative haemorrhage. Much progress has been made in the past two decades resulting in a better understanding of their biological behaviours, using modern imaging protocols, novel therapies and improvement of the conceptual framework on pathogenesis to underpin treatment decisions.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Further Reading
Buckmiller L, Richter G, Suen J. Diagnosis and management of hemangiomas and vascular malformations of the head and neck. Oral Dis. 2010;16:405–18. https://doi.org/10.1111/j.1601-0825.2010.01661.x.
Izadpanah A, Izadpanah A, Kanevsky J, et al. Propranolol versus corticosteroids in the treatment of infantile hemangioma: a systematic review and meta-analysis. Plast Reconstr Surg. 2013;131:601–13.
Mulligan PR, Prajapati HJ, Martin LG, Patel TH. Vascular anomalies: classification, imaging characteristics and implications for interventional radiology treatment approaches. Br J Radiol. 2014;87(1035):20130392. https://doi.org/10.1259/bjr.20130392.
Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982;69:412–22.
Munden A, Butschek R, Tom WL, et al. Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies. Br J Dermatol. 2014;170(04):907–13.
North PE, Waner M, Mizeracki A, et al. GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas. Hum Pathol. 2000;31:11–22.
Shirley MD, Tang H, Gallione CJ, Baugher JD, Frelin LP, Cohen B, North PE, Marchuk DA, Comi AM, Pevsner J. Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ. N Engl J Med. 2013;368(21):1971–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
De Silva, H.L., Seo, B. (2023). Blue-Purple Lump on the Lip: Haemangioma/Vascular Anomaly. In: Tilakaratne, W.M., Kallarakkal, T.G. (eds) Clinicopathological Correlation of Oral Diseases. Springer, Cham. https://doi.org/10.1007/978-3-031-24408-7_12
Download citation
DOI: https://doi.org/10.1007/978-3-031-24408-7_12
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-24407-0
Online ISBN: 978-3-031-24408-7
eBook Packages: MedicineMedicine (R0)