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Complicated Delayed Sleep Wake Phase Disorder in a 59-Year-Old Woman

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A Clinical Casebook of Sleep Disorders in Women

Abstract

This chapter presents a 59-year-old woman with delayed sleep wake phase disorder complicated by obstructive sleep apnea, parasomnias and higher than recommended doses of benzodiazepines. Historical features, diagnostic tools, and treatments are discussed. Though the prevalence of delayed sleep wake phase disorder may peak in adolescence at 4%, this disorder may persist into adulthood. Many of these adults have adapted to this sleeping pattern with jobs that allow them to sleep on a later schedule. Some of these adults, however, are distressed at missing much of the day. Like the patient described in this chapter, affected patients often present with complaints of sleep-onset insomnia with difficulty awakening in the morning making this circadian rhythm disorder difficult to distinguish from sleep onset insomnia in individuals with decades of counterproductive adaptations to their circadian rhythm disorder the desire of the patient to change becomes essential to therapeutic success.

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References

  1. Gaspar LS, Hesse J, Yalçin M, Santos B, Carvalhas-Almeida C, Ferreira M, et al. Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea. EBioMedicine. 2021;65:103248. https://doi.org/10.1016/j.ebiom.2021.103248.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American academy of sleep medicine clinical practice guideline. J Clin Sleep Med. 2017;13(2):307–49.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Barnes M, McEvoy RD, Banks S, Tarquinio N, Murray CG, Vowles N, et al. Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea. Am J Respir Crit Care Med. 2004;170(6):656–64.

    Article  PubMed  Google Scholar 

  4. Phillips CL, Grunstein MA, Darendeliler MA, Mihailidou AS, Srinivasan K, Yee BJ, et al. Health outcomes of continuous positive airway pressure versus oral appliance treatment for obstructive sleep apnea: a randomized controlled trial. Am J Respir Crit Care Med. 2013;187(8):879–87.

    Article  PubMed  Google Scholar 

  5. Valipour A, Lothaller H, Rauscher H, Zwick H, Burghuber OC, Lavie P. Gender-related differences in symptoms of patients with suspected breathing disorders in sleep: a clinical population study using the sleep disorders questionnaire. Sleep. 2007;30(3):312–9. https://doi.org/10.1093/sleep/30.3.312.

    Article  PubMed  Google Scholar 

  6. Shechter A, Cain SW. Sex effects and differences in circadian rhythms and sleep. In: Kryger MH, Roth T, Goldstein CA, editors. Principles and practice of sleep medicine. 7th ed. Philadelphia: Elsevier; 2021. p. 1734–41.

    Google Scholar 

  7. Cain SW, Chang AM, Phillips AJ, Munch MY, Gronfier C, Wyatt JK, Dijk DJ, Wright KP Jr, Czeisler CA. Sex differences in phase angle of entrainment and melatonin amplitude in humans. J Biol Rhythm. 2010;25:288–96.

    Article  CAS  Google Scholar 

  8. Duffy JF, Cain SW, Chang A-M, Phillips AJK, Münch MY, Gronfier C, et al. Sex difference in the near-24-hour intrinsic period of the human circadian timing system. Proc Natl Acad Sci U S A. 2011;108(supplement_3):15602–8. https://doi.org/10.1073/pnas.1010666108.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Hazama GI, Inoue C, Kojima K, Ueta T, Nakagone K. The prevalence of probable delayed sleep-phase syndrome in students from junior high school to university in Tottori, Japan. Tohoku J Exp Med. 2008;216(1):95–8.

    Article  PubMed  Google Scholar 

  10. Sivertsen B, Pallesen S, Stormark KM, Bøe T, Lundervold AJ, Hysing M. Delayed sleep phase syndrome in adolescents: prevalence and correlates in a large population-based study. BMC Public Health. 2013;13(1):1163. https://doi.org/10.1186/1471-2458-13-1163.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Ashbrook LH, Krystal AD, Fu YH, Ptacek LJ. Genetics of the human circadian clock and sleep homeostat. Neuropsychopharmacology. 2020;45:45–54.

    Article  PubMed  Google Scholar 

  12. Patke A, Murphy PJ, Onat OE, Krieger AC, Özçelik T, Campbell SS, et al. Mutation of the human circadian clock gene CRY1 in familial delayed sleep phase disorder. Cell. 2017;169(2):203–215.e13. https://doi.org/10.1016/j.cell.2017.03.027.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Depner CM, Melanson EL, Eckel RH, Snell-Bergeon JK, Perreault L, Bergman BC, et al. Ad libitum weekend recovery sleep fails to prevent metabolic dysregulation during a repeating pattern of insufficient sleep and weekend recovery sleep. Curr Biol. 2017;29(6):957–67.

    Article  Google Scholar 

  14. Drerup M (2020) How exercise affects your sleep and whether evening workouts keep you awake. https://health.clevelandclinic.org. Accessed 30 April 2022.

  15. Carter GS, Auger RR. Delayed sleep-wake phase disorder. In: Auger RR, editor. Circadian rhythm sleep-wake disorders: an evidence-based guide for clinicians and investigators. Cham: Springer; 2020. p. 67–90.

    Chapter  Google Scholar 

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Correspondence to Marilyn K. Culp .

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Culp, M.K., Luong, S.R., Carter, G.S. (2023). Complicated Delayed Sleep Wake Phase Disorder in a 59-Year-Old Woman. In: Khan, S.S., Khawaja, I.S. (eds) A Clinical Casebook of Sleep Disorders in Women. Springer, Cham. https://doi.org/10.1007/978-3-031-24200-7_9

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  • DOI: https://doi.org/10.1007/978-3-031-24200-7_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-24199-4

  • Online ISBN: 978-3-031-24200-7

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