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Biomedical Applications of Nanocarriers in Nasal Delivery

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Nasal Drug Delivery

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Abstract

Non-invasive drug delivery is an emerging way to target a wide range of therapeutics. One of them, i.e., the nasal drug delivery has shown promising results in delivering small and large molecules, genes, peptides, and proteins. This drug delivery system targets the drug to the brain by direct nose-to-brain and/or indirect nose-to-blood-to-brain routes. Nanocarriers play a vital role in the nasal delivery system due to their small size which provides ease in targeting. Numerous strategies have been explored by researchers for the transportation of drugs from nose to target and found excellent results in therapy. It was observed that polymeric and lipidic nanocarriers have numerous applications in targeted drug delivery, gene delivery, and vaccine delivery. Moreover, they are also used for diagnostics as well as theranostics purposes. This chapter briefly summarizes the different types of nanocarriers used for nasal delivery with their characterization techniques. Further, the biomedical applications of nanocarriers via the nasal route are discussed in detail.

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Acknowledgments

The authors would like to thank Nirma University, India for providing financial assistance in the form of Nirma University fellowship-SRF to Atul Garkal (NU/Ph.D./IP/GAD/19-20/1496).

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The authors declare that there are no conflicts of interest for this publication.

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Authors and Affiliations

  1. Department of Pharmaceutics, Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India

    Namdev Dhas, Atul Garkal, Jahanvi Patel & Tejal Mehta

  2. Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, MAHE, Manipal, India

    Namdev Dhas, Soji Neyyar, Ritu Kudarha & Srinivas Mutalik

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  1. Namdev Dhas
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  2. Soji Neyyar
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  3. Atul Garkal
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  7. Tejal Mehta
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Correspondence to Tejal Mehta .

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Editors and Affiliations

  1. Taneja College of Pharmacy, University of South Florida, Tampa, FL, USA

    Yashwant V. Pathak

  2. School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India

    Hemant K. S. Yadav

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Dhas, N. et al. (2023). Biomedical Applications of Nanocarriers in Nasal Delivery. In: Pathak, Y.V., Yadav, H.K.S. (eds) Nasal Drug Delivery. Springer, Cham. https://doi.org/10.1007/978-3-031-23112-4_7

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