Skip to main content

Early Mobilization in Patients Receiving ECMO for Respiratory Failure

  • Chapter
  • First Online:
Annual Update in Intensive Care and Emergency Medicine 2023

Part of the book series: Annual Update in Intensive Care and Emergency Medicine ((AUICEM))

  • 1350 Accesses

Abstract

It is well established that weakness and debility are common sequelae of critical illness and that participation in physical therapy programs, and in particular early mobilization in the intensive care unit (ICU), can help mitigate these effects and lead to improved outcomes. The safety and feasibility of mobilizing patients during extracorporeal membrane oxygenation (ECMO) are important considerations. Multiple studies have demonstrated that patients may be safely mobilized when appropriate screening criteria and safety protocols are in place and experienced personnel are available. In the bridge to lung transplant population, mobilization is important to maintain physical fitness in order to preserve transplant eligibility, and may improve transplant outcomes. Patients receiving ECMO as a bridge to recovery from an acute illness may also safely undergo early mobilization. Specific factors have been identified that predict the ability of patients receiving ECMO to participate in active physical therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Needham DM. Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function. JAMA. 2008;300:1685–90.

    Article  CAS  PubMed  Google Scholar 

  2. Stevens RD, Dowdy DW, Michaels RK, Mendez-Tellez PA, Pronovost PJ, Needham DM. Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Med. 2007;33:1876–91.

    Article  PubMed  Google Scholar 

  3. Fan E, Dowdy DW, Colantuoni E, et al. Physical complications in acute lung injury survivors: a 2-year longitudinal prospective study. Crit Care Med. 2014;42:849–59.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Waldauf P, Jiroutkova K, Krajcova A, Puthucheary Z, Duska F. Effects of rehabilitation interventions on clinical outcomes in critically ill patients: systematic review and meta-analysis of randomized controlled trials. Crit Care Med. 2020;48:1055–65.

    PubMed  Google Scholar 

  5. Morris PE, Goad A, Thompson C, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36:2238–43.

    Article  PubMed  Google Scholar 

  6. Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL. The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review. Intensive Care Med. 2017;43:171–83.

    Article  PubMed  Google Scholar 

  7. Nydahl P, Sricharoenchai T, Chandra S, et al. Safety of patient mobilization and rehabilitation in the intensive care unit. systematic review with meta-analysis. Ann Am Thorac Soc. 2017;14:766–77.

    Article  PubMed  Google Scholar 

  8. Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet. 2009;373:1874–82.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Hayes K, Holland AE, Pellegrino VA, Mathur S, Hodgson CL. Acute skeletal muscle wasting and relation to physical function in patients requiring extracorporeal membrane oxygenation (ECMO). J Crit Care. 2018;48:1–8.

    Article  CAS  PubMed  Google Scholar 

  10. Tipograf Y, Salna M, Minko E, et al. Outcomes of extracorporeal membrane oxygenation as a bridge to lung transplantation. Ann Thorac Surg. 2019;107:1456–63.

    Article  PubMed  Google Scholar 

  11. Chicotka S, Pedroso FE, Agerstrand CL, et al. Increasing opportunity for lung transplant in interstitial lung disease with pulmonary hypertension. Ann Thorac Surg. 2018;106:1812–9.

    Article  PubMed  Google Scholar 

  12. Abrams D, Javidfar J, Farrand E, et al. Early mobilization of patients receiving extracorporeal membrane oxygenation: a retrospective cohort study. Crit Care. 2014;18:R38.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Munshi L, Kobayashi T, DeBacker J, et al. Intensive care physiotherapy during extracorporeal membrane oxygenation for acute respiratory distress syndrome. Ann Am Thorac Soc. 2017;14:246–53.

    Article  PubMed  Google Scholar 

  14. Wells CL, Forrester J, Vogel J, Rector R, Tabatabai A, Herr D. Safety and feasibility of early physical therapy for patients on extracorporeal membrane oxygenator: University of Maryland Medical Center experience. Crit Care Med. 2018;46:53–9.

    Article  PubMed  Google Scholar 

  15. Braune S, Bojes P, Mecklenburg A, et al. Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study. Ann Intensive Care. 2020;10:161.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Abrams D, Madahar P, Eckhardt CM, et al. Early mobilization during extracorporeal membrane oxygenation for cardiopulmonary failure in adults: factors associated with intensity of treatment. Ann Am Thorac Soc. 2022;19:90–8.

    Article  PubMed  Google Scholar 

  17. Mustafa AK, Alexander PJ, Joshi DJ, et al. Extracorporeal membrane oxygenation for patients with COVID-19 in severe respiratory failure. JAMA Surg. 2020;155:990–2.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Mustafa AK, Tatooles AJ. Extracorporeal membrane oxygenation and coronavirus disease 2019—reply. JAMA Surg. 2021;156:403.

    Article  PubMed  Google Scholar 

  19. Ramanathan K, Shekar K, Ling RR, et al. Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis. Crit Care. 2021;25:211.

    Article  PubMed  PubMed Central  Google Scholar 

  20. ECMO-PT Study Investigators; International ECMO Network. Early mobilisation during extracorporeal membrane oxygenation was safe and feasible: a pilot randomised controlled trial. Intensive Care Med. 2020;46:1057–9.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to D. Abrams .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Melville, K.E., Brodie, D., Abrams, D. (2023). Early Mobilization in Patients Receiving ECMO for Respiratory Failure. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2023. Annual Update in Intensive Care and Emergency Medicine. Springer, Cham. https://doi.org/10.1007/978-3-031-23005-9_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-23005-9_19

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-23004-2

  • Online ISBN: 978-3-031-23005-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics