Abstract
It is well established that weakness and debility are common sequelae of critical illness and that participation in physical therapy programs, and in particular early mobilization in the intensive care unit (ICU), can help mitigate these effects and lead to improved outcomes. The safety and feasibility of mobilizing patients during extracorporeal membrane oxygenation (ECMO) are important considerations. Multiple studies have demonstrated that patients may be safely mobilized when appropriate screening criteria and safety protocols are in place and experienced personnel are available. In the bridge to lung transplant population, mobilization is important to maintain physical fitness in order to preserve transplant eligibility, and may improve transplant outcomes. Patients receiving ECMO as a bridge to recovery from an acute illness may also safely undergo early mobilization. Specific factors have been identified that predict the ability of patients receiving ECMO to participate in active physical therapy.
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References
Needham DM. Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function. JAMA. 2008;300:1685–90.
Stevens RD, Dowdy DW, Michaels RK, Mendez-Tellez PA, Pronovost PJ, Needham DM. Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Med. 2007;33:1876–91.
Fan E, Dowdy DW, Colantuoni E, et al. Physical complications in acute lung injury survivors: a 2-year longitudinal prospective study. Crit Care Med. 2014;42:849–59.
Waldauf P, Jiroutkova K, Krajcova A, Puthucheary Z, Duska F. Effects of rehabilitation interventions on clinical outcomes in critically ill patients: systematic review and meta-analysis of randomized controlled trials. Crit Care Med. 2020;48:1055–65.
Morris PE, Goad A, Thompson C, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36:2238–43.
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, Hodgson CL. The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review. Intensive Care Med. 2017;43:171–83.
Nydahl P, Sricharoenchai T, Chandra S, et al. Safety of patient mobilization and rehabilitation in the intensive care unit. systematic review with meta-analysis. Ann Am Thorac Soc. 2017;14:766–77.
Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet. 2009;373:1874–82.
Hayes K, Holland AE, Pellegrino VA, Mathur S, Hodgson CL. Acute skeletal muscle wasting and relation to physical function in patients requiring extracorporeal membrane oxygenation (ECMO). J Crit Care. 2018;48:1–8.
Tipograf Y, Salna M, Minko E, et al. Outcomes of extracorporeal membrane oxygenation as a bridge to lung transplantation. Ann Thorac Surg. 2019;107:1456–63.
Chicotka S, Pedroso FE, Agerstrand CL, et al. Increasing opportunity for lung transplant in interstitial lung disease with pulmonary hypertension. Ann Thorac Surg. 2018;106:1812–9.
Abrams D, Javidfar J, Farrand E, et al. Early mobilization of patients receiving extracorporeal membrane oxygenation: a retrospective cohort study. Crit Care. 2014;18:R38.
Munshi L, Kobayashi T, DeBacker J, et al. Intensive care physiotherapy during extracorporeal membrane oxygenation for acute respiratory distress syndrome. Ann Am Thorac Soc. 2017;14:246–53.
Wells CL, Forrester J, Vogel J, Rector R, Tabatabai A, Herr D. Safety and feasibility of early physical therapy for patients on extracorporeal membrane oxygenator: University of Maryland Medical Center experience. Crit Care Med. 2018;46:53–9.
Braune S, Bojes P, Mecklenburg A, et al. Feasibility, safety, and resource utilisation of active mobilisation of patients on extracorporeal life support: a prospective observational study. Ann Intensive Care. 2020;10:161.
Abrams D, Madahar P, Eckhardt CM, et al. Early mobilization during extracorporeal membrane oxygenation for cardiopulmonary failure in adults: factors associated with intensity of treatment. Ann Am Thorac Soc. 2022;19:90–8.
Mustafa AK, Alexander PJ, Joshi DJ, et al. Extracorporeal membrane oxygenation for patients with COVID-19 in severe respiratory failure. JAMA Surg. 2020;155:990–2.
Mustafa AK, Tatooles AJ. Extracorporeal membrane oxygenation and coronavirus disease 2019—reply. JAMA Surg. 2021;156:403.
Ramanathan K, Shekar K, Ling RR, et al. Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis. Crit Care. 2021;25:211.
ECMO-PT Study Investigators; International ECMO Network. Early mobilisation during extracorporeal membrane oxygenation was safe and feasible: a pilot randomised controlled trial. Intensive Care Med. 2020;46:1057–9.
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Melville, K.E., Brodie, D., Abrams, D. (2023). Early Mobilization in Patients Receiving ECMO for Respiratory Failure. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2023. Annual Update in Intensive Care and Emergency Medicine. Springer, Cham. https://doi.org/10.1007/978-3-031-23005-9_19
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DOI: https://doi.org/10.1007/978-3-031-23005-9_19
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