Abstract
Esophageal non-traumatic emergencies are more common as compared to the traumatic etiology and are mostly represented by iatrogenic perforation, barogenic (Boerhaave) perforation, foreign body ingestion, complications of reconstructive esophageal surgery, descending necrotizing mediastinitis, and esophageal bleeding. In general, esophageal emergencies are rare but burdened with high morbidity and mortality if not recognized and treated promptly. Early diagnosis, stratification of risk score at presentation, and individualized treatment are consistently recommended, but management strategies vary widely and are influenced by the patient’s physiologic status, type of clinical presentation, site and size of injury, hospital setting, and locally available expertise. A high degree of suspicion is recommended in clinical situations that may be associated with or have the potential to progress to esophageal perforation. Both computed tomography (CT) scan and endoscopy are reliable diagnostic tools and their use should be tailored to the patient’s conditions in order not to miss subtle findings that may significantly impact clinical decision-making and prognosis. Endoscopic and surgical approach still represents the mainstay of therapy. Hybrid minimally invasive techniques, including interventional radiology/endoscopy and/or thoracoscopy/laparoscopy, are effective and increasingly used in centers where multidisciplinary expertise is available. Non-operative management is a reasonable option in carefully selected patients, but a low threshold of alert and an aggressive policy of percutaneous drainage are mandatory to control sepsis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Singer M, Deutschman CS, Seymour CW. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA. 2016;315(8):801–10.
van der Steen M, Verhage R, Singer M, Pickkers P. Overview of the third international consensus definitions for sepsis and shock (sepsis-3). Neth J Crit Care. 2016;24:6–9.
Wahed S, Dent B, Jones R, Griffrin SM. Spectrum of oesophageal perforations and their influence on management. Br J Surg. 2014;101:e156–62.
Axtell AL, Gaissert HA, Morse CR, et al. Management and outcomes of esophageal perforation. Dis Esophagus. 2021;35(1):doab039. https://doi.org/10.1093/dote/doab039.
Wu JT, Mattox KL, Wall MJ. Esophageal perforations: new perspectives and treatment paradigms. J Trauma. 2007;63:1173–84.
Korn O, Onate JC, Lopez R. Anatomy of the Boerhave syndrome. Surgery. 2007;141:222–8.
Griffin SM, Lamb PJ, Shenfine J, et al. Spontaneous rupture of the oesophagus. Br J Surg. 2008;95:115–20.
Schweigert M, Sousa HS, Solymosi N, et al. Spotlight on esophageal perforation: a multinational study using the Pittsburgh esophageal perforation severity scoring system. J Thorac Cardiovasc Surg. 2016;151(4):1002–9.
Wigley C, Athanasiou A, Bhatti A, et al. Does the Pittsburgh Severity Score predict outcome in esophageal perforation? Dis Esophagus. 2019;32(2):doy109. https://doi.org/10.1093/dote/doy109.
Chirica M, Kelly MD, Siboni S, et al. Esophageal emergencies: WSES guidelines. World J Emerg Surg. 2019;14(1):20. https://doi.org/10.1186/s13017-019-0245-2.20.
Hill LD. Incarcerated paraesophageal hernia. A surgical emergency. Am J Surg. 1973;126:286–91.
Bonavina L, Inaba K. Incarcerated hiatal hernia. In: Galante J, Coimbra R, editors. Thoracic surgery for the acute surgeon, hot topics in acute care surgery and trauma. Cham: Springer Nature; 2021. p. 43–51.
Sinha R. Naclerio’s V sign. Radiology. 2007;245:296–7.
Aiolfi A, Ferrari D, Riva CG, Toti F, Bonitta GL, Bonavina L. Esophageal foreign bodies in adults: systematic review of the literature. Scand J Gastroenterol. 2018;53(10–11):1171–8. https://doi.org/10.1080/00365521.2018.1526317.
Ferrari D, Siboni S, Riva CG, et al. Esophageal foreign bodies: observational cohort study and factors associated with recurrent impaction. Eur J Gastroenterol Hepatol. 2020;32(7):827–31.
Verstegen MHP, Bouwense SAW, van Workum F, et al. Management of intrathoracic and cervical anastomotic leakage after esophagectomy for esophageal cancer: a systematic review. World J Emerg Surg. 2019;14:17. https://doi.org/10.1186/s13017-019-0235-4.
Brenkman HJF, Parry K, Noble F, et al. Hiatal hernia after esophagectomy for cancer. Ann Thorac Surg. 2017;103:1055–62.
Lagarde SM, Omloo JMT, de Jong K, et al. Incidence and management of chyle leakage after esophagectomy. Ann Thorac Surg. 2005;80:449–54.
Asti E, Bonitta G, Melloni M, et al. Utility of C-reactive protein as predictive biomarker of anastomotic leak after minimally invasive esophagectomy. Langenbecks Arch Surg. 2018;403:235–44. https://doi.org/10.1007/s00423-018-1663-4.
Dindo D, Demartines N, Clavien PA. Classification of surgical complications. A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13.
Low DE, Alderson D, Cecconello I, et al. International consensus on standardization of data collection for complications associated with esophagectomy: esophagectomy complications consensus group (ECCG). Ann Surg. 2015;262:286–94.
Ridder GJ, Maier W, Kinzer S, et al. Descending necrotizing mediastinitis. Contemporary trends in etiology, diagnosis, management, and outcome. Ann Surg. 2010;251(3):528–34.
Wangrattanapranee P, Khrucharoen U, Jensen DM, et al. Severe upper gastrointestinal hemorrhage caused by reflux esophagitis. Dig Dis Sci. 2022;67:159–69.
Byrne JJ, Moran JM. The Mallory–Weiss syndrome. N Engl J Med. 1965;272:398–400.
Gurvits GE, Cherian K, Shami MF, et al. Black esophagus: new insights and multicenter international experience in 2014. Dig Dis Sci. 2015;60:444–53.
Hollander JE, Quick J. Aortoesophageal fistula: a comprehensive review of the literature. Am J Med. 1991;91:279–87.
Grimaldi S, Milito P, Lovece A, et al. Dysphagia aortica. Eur Surg. 2021;54:228–39. https://doi.org/10.1007/s10353-021-00741-9.
Karstensen JG, Ebigbo A, Bhat P, et al. Endoscopic treatment of variceal upper gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Cascade guideline. Endosc Intern Open. 2020;8:E990–7.
Kuppusamy M, Hubka M, Felisky CD, et al. Evolving management strategies in esophageal perforation: surgeons using nonoperative techniques to improve outcomes. J Am Coll Surg. 2011;213:164–72.
Biancari F, Saarnio J, Mennander A, et al. Outcome of patients with esophageal perforations: a multicenter study. World J Surg. 2014;38(4):902–9.
Biancari F, Gudbjartsson T, Mennander A, et al. Treatment of esophageal perforation in octogenarians: a multicenter study. Dis Esophagus. 2014;27(8):715–8.
Ali JT, Rice RD, David EA, et al. Perforated esophageal intervention focus (PERF) study: a multi-center examination of contemporary treatment. Dis Esophagus. 2017;30:1–8.
Altorjay A, Kiss J, Voros A, et al. Nonoperative management of esophageal perforations. Is it justified? Ann Surg. 1997;225(4):415–21.
Sudarshan M, Elharram M, Spicer J, et al. Management of esophageal perforation in the endoscopic era: is operative repair still relevant? Surgery. 2016;160(4):1104–10.
Abbas G, Schuchert MJ, Pettiford BL, et al. Contemporaneous management of esophageal perforation. Surgery. 2009;146(4):749–55.
Ferguson MK, Reeder LB, Olak J. Outcome after failed initial therapy for rupture of the esophagus or intrathoracic stomach. J Gastrointest Surg. 1997;1:34–9.
Conti M, Pougeoise M, Wurtz A, et al. Management of postintubation tracheobronchial ruptures. Chest. 2006;130:412–8.
Foroulis CN, Nana C, Kleontas A, et al. Repair of post-intubation tracheoesophageal fistulas through the left pre-sternocleidomastoid approach: a recent case-series of 13 patients. J Thorac Dis. 2015;7(S1):S20–6.
Sdralis EIK, Petousis S, Rashid F, et al. Epidemiology, diagnosis and management of esophageal perforations: systematic review. Dis Esophagus. 2017;30(8):1–6.
Tang A, Ahmad U, Raja S, et al. Repair, reconstruct, or divert. The fate of the perforated esophagus. Ann Surg. 2021;274:e417–24.
Bona D, Aiolfi A, Rausa E, Bonavina L. Management of Boerhaave’s syndrome with an over-the-scope-clip. Eur J Cardio Thorac Surg. 2013;45:752–4.
Moore CB, Almoghrabi O, Hofstetter W, Veeramachanen N. Endoluminal wound vac: an evolving role in treatment of esophageal perforation. J Vis Surg. 2020;6:43.
Vermeulen BD, Van der Leeden B, Ali JT, et al. Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta-analysis. Surg Endosc. 2020;35:3492–505. https://doi.org/10.1007/s00464-020-07806-y.
Bardini R, Bonavina L, Pavanello M, Asolati M, Peracchia A. Temporary double exclusion of the perforated esophagus using absorbable staples. Ann Thorac Surg. 1992;54:1165–7.
Thal AP, Hatafuku T. Improved operation for esophageal rupture. JAMA. 1964;188:126–8.
Bawahab M, Mitchell P, Church N, Debru E. Management of acute paraesophageal hernia. Surg Endosc. 2009;23:255–9.
Tsang TK, Walker R, Yu DJ. Endoscopic reduction of gastric volvulus: the alpha-loop maneuver. Gastrointest Endosc. 1995;42:244–8.
Kercher KW, Matthews BD, Ponsky JL, et al. Minimally invasive management of paraesophageal herniation in the high-risk surgical patient. Am J Surg. 2001;182:510–4.
Light D, Links D, Griffin M. The threatened stomach: management of the acute gastric volvulus. Surg Endosc. 2016;30:1847–52.
Ferrari D, Aiolfi A, Bonitta G, et al. Flexible versus rigid endoscopy in the management of esophageal foreign body impaction: systematic review and meta-analysis. World J Emerg Surg. 2018;13:42.
Bonavina L, Aiolfi A, Siboni S, Rausa E. Thoracoscopic removal of dental prosthesis impacted in the upper thoracic esophagus. World J Emerg Surg. 2014;9:5.
Rausa E, Asti E, Aiolfi A, Bianco F, Bonitta G, Bonavina L. Comparison of endoscopic vacuum therapy versus endoscopic stenting for esophageal leaks: systematic review and meta-analysis. Dis Esophagus. 2018;31(11):doy060. https://doi.org/10.1093/dote/doy060.
Van Boeckel PGA, Sijbring A, Vleggaar FP, Siersema PD. Systematic review: temporary stent placement for benign rupture or anastomotic leak of the oesophagus. Aliment Pharmacol Ther. 2011;33(12):1292–301.
Dent B, Griffin SM, Jones R, Wahed S, Immanuel A, Hayes N. Management and outcomes of anastomotic leaks after oesophagectomy. Br J Surg. 2016;103:1033–8.
Bonavina L, Saino G, Bona D, et al. Thoracoscopic management of chylothorax complicating esophagectomy. J Laparoendosc Surg Adv Surg Tech. 2001;11(6):367–9.
Chiesa R, Melissano G, Marone EM, et al. Endovascular treatment of aortoesophageal and aortobronchial fistulae. J Vasc Surg. 2010;51:1195–202.
Escorsell A, Pavel O, Cardenas A, et al. Esophageal balloon tamponade versus esophageal stent in controlling acute refractory variceal bleeding: a multicenter randomized controlled trial. Hepatology. 2016;63:1957–67.
Further Reading
Cameron JL, Kieffer RF, Hendrix TR, et al. Selective non operative management of contained intrathoracic esophageal disruptions. Ann Thorac Surg. 1979;27:404–8.
Chirica M, Kelly MD, Siboni S, et al. Esophageal emergencies: WSES guidelines. World J Emerg Surg. 2019;14:26. https://doi.org/10.1186/s13017-019-0245-2.20.
Griffin SM, Lamb PJ, Shenfine J, et al. Spontaneous rupture of the oesophagus. Br J Surg. 2008;95:115–20.
Kuppusamy M, Hubka M, Felisky CD, et al. Evolving management strategies in esophageal perforation: surgeons using nonoperative techniques to improve outcomes. J Am Coll Surg. 2011;213:164–72.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Bonavina, L., Asti, E., Tonucci, T.P. (2023). Esophageal Non-traumatic Emergencies. In: Coccolini, F., Catena, F. (eds) Textbook of Emergency General Surgery. Springer, Cham. https://doi.org/10.1007/978-3-031-22599-4_56
Download citation
DOI: https://doi.org/10.1007/978-3-031-22599-4_56
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-22598-7
Online ISBN: 978-3-031-22599-4
eBook Packages: MedicineMedicine (R0)