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Home Parenteral Support for Patients with Incurable Advance Cancer

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Intestinal Failure

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Abstract

The use of long-term home parenteral support (HPS) for patients with incurable advanced cancer in the palliative phase of disease is a common indication in many countries, though the prevalence varies for historic, cultural and economic reasons. The detrimental effects of malnutrition and cachexia for this group of patients is well documented. HPS is used for a small select group of patients with advanced incurable cancers. It is a burdensome treatment with high associated costs for patients with incurable advanced cancers. It can be used to negate the negative effects of dehydration and malnutrition, with emerging evidence suggesting cachexia previously considered refractory, can be reversed or halted, leading to increased survival time and improved quality of life in selected patients. The positive impacts of treatment are most evident in patients with a high performance status and a low burden of an inflammatory state at the time of commencing HPS. Optimised patient selection, including a multidisciplinary approach with patient involvement, will lead to greater benefits from treatments and be more cost effective.

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Authors and Affiliations

  1. Department of Gastroenterology, St Mark’s Hospital, London, UK

    Mani Naghibi

  2. Faculty of Medicine, University of Medicine, Milan, Italy

    Federico Bozzetti

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  1. Mani Naghibi
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  2. Federico Bozzetti
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Correspondence to Mani Naghibi .

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  1. St Mark’s Hospital, Harrow, Middlesex, UK

    Jeremy M.D. Nightingale

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Naghibi, M., Bozzetti, F. (2023). Home Parenteral Support for Patients with Incurable Advance Cancer. In: Nightingale, J.M. (eds) Intestinal Failure. Springer, Cham. https://doi.org/10.1007/978-3-031-22265-8_49

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