Abstract
Vessel segmentation is an important step for cerebrovascular disease analysis, while automatic and complete segmentation of head and neck vessels in CT angiography is a challenging problem. The reason is that vessels have diverse shapes and sizes in long and tortuous tubular-like vasculatures, as well as confounding appearance with surrounding tissues. Current deep learning-based methods often use voxel-wise segmentation, without considering the shape or connectivity of segmented vessels. In this paper, we describe vascular structures using affinity maps and construct connectivity priors of vessels so as to establish a topological connectivity loss for vessel segmentation. Specifically, a multi-head 3D U-Net is applied to predict the segmentation mask and the affinity map, and subsequently the connectivity-aware affinity map is used to refine the segmentation. In experiments, we applied our method on 72 head and neck CT angiography images. Voxel-wise and topology-relevant metrics show that the proposed method achieved superior performance than the widely used 3D nnU-Net and provided better 3D vessel visualization results.
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This work was supported in part by the National Key Research and Development Program of China under Grant 2018YFC0116400.
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Yao, L. et al. (2022). Head and Neck Vessel Segmentation with Connective Topology Using Affinity Graph. In: Lian, C., Cao, X., Rekik, I., Xu, X., Cui, Z. (eds) Machine Learning in Medical Imaging. MLMI 2022. Lecture Notes in Computer Science, vol 13583. Springer, Cham. https://doi.org/10.1007/978-3-031-21014-3_24
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