Skip to main content

Exocrine Glands (Salivary Gland and Pancreas)

  • Chapter
  • First Online:
Normal Cytology
  • 450 Accesses

Abstract

This chapter details the cytomorphologic spectrum of normal elements of the salivary gland and pancreas. Diagnostic pitfalls associated with misinterpretation of benign cells as malignancy in salivary gland aspirates are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Sandrine Jousse-Joulin. Chapter 17: Salivary glands. In: Wakefield RJ, D’Agostino MA, eds. Essential applications of musculoskeletal ultrasound in rheumatology. W.B. Saunders Philadelphia, PA, 2010: 199-206.

    Chapter  Google Scholar 

  2. Xu L, Lal K, Santarpia RP III, Pollock JJ. Salivary proteolysis of histidine-rich polypeptides and the antifungal activity of peptide degradation products. Arch Oral Biol. 1993;38(4):277–83.

    Article  CAS  Google Scholar 

  3. Caselitz J, Jaup T, Seifert G. Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue. Virchows Arch A Pathol Anat Histol. 1981;394(1–2):61–73.

    Article  CAS  Google Scholar 

  4. Takano K, Malamud D, Bennick A, Oppenheim F, Hand AR. Localization of salivary proteins in granules of human parotid and submandibular acinar cells. Crit Rev Oral Biol Med. 1993;4(3–4):399–405.

    Article  CAS  Google Scholar 

  5. Langdon JD. Chapter 1: Surgical anatomy, embryology, and physiology of the salivary glands. In: Carlson ER, Ord RA, editors. Textbook and color atlas of salivary gland pathology diagnosis and management. London: Wiley-Blackwell; 2008. p. 3.

    Google Scholar 

  6. de Paula F, Teshima THN, Hsieh R, Souza MM, Nico MMS, Lourenco SV. Overview of human salivary glands: highlights of morphology and developing processes. Anat Rec. 2017;300(7):1180–8.

    Article  Google Scholar 

  7. Nanci A. Chapter 12: Oral mucosa. In: Nanci A, editor. Ten cate’s oral histology: development, structure, and function. 8th ed. Amsterdam: Elsevier; 2013. p. 275.

    Google Scholar 

  8. Schmidt RL, Hall BJ, Wilson AR, Layfield LJ. A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions. Am J Clin Pathol. 2011;136(1):45–59.

    Article  Google Scholar 

  9. Layfield LJ. Fine-needle aspiration in the diagnosis of head and neck lesions: a review and discussion of problems in differential diagnosis. Diagn Cytopathol. 2007;35(12):798–805.

    Article  Google Scholar 

  10. Liu CC, Jethwa AR, Khariwala SS, Johnson J, Sensitivity SJJ. Specificity, and posttest probability of parotid fine-needle aspiration: a systematic review and meta-analysis. Otolaryngol Head Neck Surg. 2016;154(1):9–23.

    Article  Google Scholar 

  11. Hruban RH, Pitman MB, Klimstra DS. Chapter 1: The normal pancreas. In: Silverberg SG, editor. AFIP Atlas of tumor pathology, Fourth series, Fascicle tumors of the pancreas. Washington, DC: American Registry of Pathology; 2007. p. 1–15, in collaboration with the Armed Forces Institute of Pathology, Washington, DC.

    Google Scholar 

  12. Longnecker DS. Anatomy and histology of the pancreas. Pancreapedia: Exocrine Pancreas Knowledge Base. 2021; https://doi.org/10.3998/panc.2021.01.

  13. Chang EB, Leung PS. Pancreatic physiology. In: Leung P, editor. The gastrointestinal system. Dordrecht: Springer; 2014. p. 87–105. https://doi.org/10.1007/978-94-017-8771-0_4.

    Chapter  Google Scholar 

  14. Siegel CS, Slimstra DS. Cytomorphologic and immunophenotypical features of acinar cell neoplasms of the pancreas. Cancer Cytopathol. 2013;121:459–70.

    Article  Google Scholar 

  15. Lin F, Staerkel G. Cytologic criteria for well differentiated adenocarcinoma of the pancreas in fine-needle aspiration biopsy specimens. Cancer Cytopathol. 2003;99:44–50.

    Article  Google Scholar 

  16. Samedi VG, Bocklage T. Chapter 5: Pancreaticobiliary tract. In: Siddiqui M, editor. Pitfalls in diagnostic cytopathology with key differentiating cytologic features, essentials in cytopathology 27. Springer: Cham; 2016. p. 103–6.

    Chapter  Google Scholar 

  17. Schreiner AM, Mansoor A, Faigel DO, Morgan TK. Intrapancreatic accessory spleen: mimic of pancreatic endocrine tumor diagnosed by endoscopic ultrasound-guided fine-needle aspiration biopsy. Diagn Cytopathol. 2008;36(4):262–5.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Madelyn Lew .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Lew, M., Pang, J. (2022). Exocrine Glands (Salivary Gland and Pancreas). In: Lew, M., Pang, J., Pantanowitz, L. (eds) Normal Cytology. Springer, Cham. https://doi.org/10.1007/978-3-031-20336-7_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-20336-7_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-20335-0

  • Online ISBN: 978-3-031-20336-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics