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Body Cavities (Mesothelium, Synovium)

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Normal Cytology

Abstract

The major serosal body cavities of the thorax, pericardium, and abdomen are lined by a monolayer of mesothelial cells. The body cavity wall (parietes) and the organs (viscera) are lined by mesothelium. The pleura covers the lung and hemithorax, the pericardium covers and surrounds the heart, and the peritoneum lines most of the abdomen and envelops many of its organs. Effusions, excess fluid in a body cavity, are always due to a pathologic process and are frequently evaluated by cytology to differentiate between a benign or malignant process. Synovium is composed of two to three layers of synoviocytes that line joint cavities. This chapter discusses the cytomorphology of normal mesothelium and synovium.

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References

  1. DeMay RM. Chapter 3. Fluids. In: DeMay RM, editor. The art & science of cytopathology. Exfoliative cytology. 2nd ed. Chicago: American Society for Clinical Pathology Press; 2012. p. 268–89, 338-341.

    Google Scholar 

  2. Naylor B. Chapter 19. Pleural, peritoneal, and pericardial effusions. In: Bibbo M, Wilbur D, editors. Comprehensive cytopathology. 3rd ed. Amsterdam: Elsevier; 2008. p. 515–35.

    Chapter  Google Scholar 

  3. Samedi VG, Bocklage T. Chapter 10: body cavity fluids. In: Siddiqui M, editor. Pitfalls in diagnostic cytopathology with key differentiating cytologic features, essentials in cytopathology, vol. 27. Springer: Cham; 2016. p. 183–93.

    Chapter  Google Scholar 

  4. Cibas ES. Chapter 4. Pleural pericardial, and peritoneal fluids. In: Cibas ES, Ducatman BS, editors. Cytology diagnostic principles and clinical correlates. 4th ed. Amsterdam: Elsevier; 2014. p. 127–31.

    Google Scholar 

  5. Rooper LM, Ali SZ, Olson MT. A minimum volume of 75 ml is needed to ensure adequacy in a pleural effusion: a retrospective analysis of 2540 cases. Cancer Cytopathol. 2014;122(9):657–65.

    Article  Google Scholar 

  6. Cibas ES. Chapter 5. Peritoneal washings. In: Cibas ES, Ducatman BS, editors. Cytology diagnostic principles and clinical correlates. 4th ed. Amsterdam: Elsevier; 2014. p. 155–60.

    Google Scholar 

  7. Mutsaers SE. The mesothelial cell. Int J Biochem Cell Biol. 2004;36(1):9–16.

    Article  CAS  Google Scholar 

  8. Wojcik EM, Naylor B. “Collagen balls” in peritoneal washings. Prevalence, morphology, origin and significance. Acta Cytol. 1992;36(4):466–70.

    CAS  Google Scholar 

  9. Hasteh F, Lin GY, Weidner N, Michael CW. The use of immunohistochemistry to distinguish reactive mesothelial cells from malignant mesothelioma in cytologic effusions. Cancer Cytopathol. 2010;118(2):90–6.

    Article  Google Scholar 

  10. Vojtek M, Walsh MD, Papadimos DF, Shield PW. Claudin-4 immunohistochemistry is a useful pan-carcinoma marker for serous effusion specimens. Cytopathology. 2019;30:614–9.

    Article  Google Scholar 

  11. O’Connell JX. Pathology of the synovium. Am J Clin Pathol. 2000;114:773–84.

    Article  Google Scholar 

  12. Smith MD. The normal synovium. Open Rheumatol J. 2011;5:100–6.

    Article  Google Scholar 

  13. Mundt LA, Shanahan K. Chapter 11. Synovial fluid. In: Mundt LA, editor. Graff’s textbook of routine urinalysis and body fluids. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2011. p. 253–60.

    Google Scholar 

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Correspondence to Judy Pang .

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Pang, J. (2022). Body Cavities (Mesothelium, Synovium). In: Lew, M., Pang, J., Pantanowitz, L. (eds) Normal Cytology. Springer, Cham. https://doi.org/10.1007/978-3-031-20336-7_13

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  • DOI: https://doi.org/10.1007/978-3-031-20336-7_13

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