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Thermal Radiomics for Improving the Interpretability of Breast Cancer Detection from Thermal Images

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Artificial Intelligence over Infrared Images for Medical Applications and Medical Image Assisted Biomarker Discovery (MIABID 2022, AIIIMA 2022)

Abstract

Mortality rates of breast cancer are expected to increase over the next 10 years. Detection of cancers in their early stage can help in combating this disease and improving the survival rates. The traditional breast cancer detection techniques that worked in high income countries might not be applicable in low- and middle-income countries owing to implementation challenges. Thermography is re-emerging as an affordable imaging modality to enable screening in these countries. However, manual interpretation of thermograms is subjective and not accurate. Thermalytix is a novel fusion of machine learning and thermography to alleviate the subjectivity and improve the accuracy and interpretability of breast cancer detection. In this paper, we discuss three different thermal radiomics employed by Thermalytix to characterize different thermal patterns in the breast region. These thermal radiomics are interpretable and play an important role in clinical adaptation. When we tested Thermalytix with these radiomics on thermal data obtained from two different clinical studies involving 717 women, it resulted in an AUROC of 0.944 with a sensitivity and specificity of 90.6% and 85.3%, respectively. This shows the potential of Thermalytix as a promising tool for breast cancer detection.

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References

  1. Sung, H., et al.: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71(3), 209–249 (2021)

    Article  Google Scholar 

  2. Kakileti, S.T.: Machine learning for breast cancer diagnosis in developing Countries. Doctoral Thesis, Maastricht University. ProefschriftMaken (2020)

    Google Scholar 

  3. Nickson, C., Kavanagh, A.M.: Tumour size at detection according to different measures of mammographic breast density. J. Med. Screen. 16(3), 140–146 (2009)

    Article  Google Scholar 

  4. Kakileti, S.T., Manjunath, G.: AIM for breast thermography. In: Artificial Intelligence in Medicine, pp. 1–16 (2020)

    Google Scholar 

  5. Kakileti, S.T., Manjunath, G., Madhu, H., Ramprakash, H.V.: Advances in breast thermography. In: IntechOpen, p. 91 (2017)

    Google Scholar 

  6. Rassiwala, M., et al.: Evaluation of digital infra–red thermal imaging as an adjunctive screening method for breast carcinoma: a pilot study. Int. J. Surg. 12(12), 1439–1443 (2014)

    Article  Google Scholar 

  7. Omranipour, R., et al.: Comparison of the accuracy of thermography and mammography in the detection of breast cancer. Breast Care 11(4), 260–264 (2016)

    Article  Google Scholar 

  8. Baker, L.H.: Breast cancer detection demonstration project: five-year summary report. CA: A Cancer J. Clin. 32(4), 194–225 (1982)

    Google Scholar 

  9. Keyserlingk, J.R., Ahlgren, P.D., Yu, E., Belliveau, N., Yassa, M.: Functional infrared imaging of the breast. IEEE Eng. Med. Biol. Mag. 19(3), 30–41 (2000)

    Article  Google Scholar 

  10. Borchartt, T.B., Conci, A., Lima, R.C., Resmini, R., Sanchez, A.: Breast thermography from an image processing viewpoint: a survey. Signal Process. 93(10), 2785–2803 (2013)

    Article  Google Scholar 

  11. Singh, D., Singh, A.K.: Role of image thermography in early breast cancer detection-Past, present and future. Comput. Methods Programs Biomed. 183, 105074 (2020)

    Article  Google Scholar 

  12. Bratko, I.: Machine learning: between accuracy and interpretability. In: Learning, Networks and Statistics, pp. 163–177. Springer, Vienna (1997)

    Chapter  MATH  Google Scholar 

  13. Vellido, A.: The importance of interpretability and visualization in machine learning for applications in medicine and health care. Neural Comput. Appl. 32(24), 18069–18083 (2019). https://doi.org/10.1007/s00521-019-04051-w

    Article  Google Scholar 

  14. Kakileti, S.T., Madhu, H.J., Manjunath, G., Wee, L., Dekker, A., Sampangi, S.: Personalized risk prediction for breast cancer pre-screening using artificial intelligence and thermal radiomics. Artif. Intell. Med. 105, 101854 (2020)

    Article  Google Scholar 

  15. Madhu, H., Kakileti, S.T., Venkataramani, K., Jabbireddy, S.: Extraction of medically interpretable features for classification of malignancy in breast thermography. In: 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1062–1065. IEEE (2016)

    Google Scholar 

  16. Kakileti, S.T., Venkataramani, K.: Automated blood vessel extraction in two-dimensional breast thermography. In: 2016 IEEE International Conference on Image Processing (ICIP), pp. 380–384. IEEE (2016)

    Google Scholar 

  17. Singh, A., et al.: Multicentric study to evaluate the effectiveness of Thermalytix as compared with standard screening modalities in subjects who show possible symptoms of suspected breast cancer. BMJ Open 11(10), e052098 (2021)

    Article  Google Scholar 

  18. Bansal, R., Aggarwal, B., Krishnan, L.: A prospective study of an AI-based breast cancer screening solution for resource-constrained settings. J. Clin. Oncol. 39(15_suppl), e13586–e13586 (2021)

    Article  Google Scholar 

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Correspondence to Raghav Shrivastava .

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Shrivastava, R., Kakileti, S.T., Manjunath, G. (2022). Thermal Radiomics for Improving the Interpretability of Breast Cancer Detection from Thermal Images. In: Kakileti, S.T., et al. Artificial Intelligence over Infrared Images for Medical Applications and Medical Image Assisted Biomarker Discovery. MIABID AIIIMA 2022 2022. Lecture Notes in Computer Science, vol 13602. Springer, Cham. https://doi.org/10.1007/978-3-031-19660-7_1

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  • DOI: https://doi.org/10.1007/978-3-031-19660-7_1

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