Abstract
The assessment of thyroid nodule composition is an important aspect of the determination of a given nodule’s risk of malignancy. Along with other ultrasound and clinical characteristics, thyroid nodule composition will impact the decision to pursue fine needle aspiration. Nodule composition is described based on the ratio of cystic to solid components. Predominantly cystic and spongiform nodules are most likely benign. For solid nodules, based on their size and other nodule characteristics, fine needle aspiration can help determine the likelihood of malignancy.
In this chapter, images and descriptions of the various types of nodule composition are reviewed. An interesting case based on nodule composition is presented, and challenges in interpretation of ultrasound findings are also discussed.
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Further Reading
Chung R, Kim D. Imaging of thyroid nodules. Appl Radiol. https://www.appliedradiology.com/Communities/Pediatric-Imaging/imaging-of-thyroid-nodules
Haugen BR, et al. Management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26(1):1–133.
Kim JY, Kim E-K, Lee HS, Kwak JY. Conventional papillary thyroid carcinoma: effects of cystic changes visible on ultrasonography on disease prognosis. Ultrasonography. 2014;33(4):291–7.
Mokhtari M, Kumar PV, Hayati K. Fine-needle aspiration study of cystic papillary thyroid carcinoma: rare cytological findings. J Cytol. 2016;33(3):120–4.
Yang GCH, Stern CM, Messina AV. Cystic papillary thyroid carcinoma in fine needle aspiration may represent a subset of the encapsulated variant in WHO classification. Diagn Cytopathol. 2009;38(10):721–6.
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Eldeiry, L.S. (2023). Thyroid Nodule Composition. In: Eldeiry, L.S., Laver, N.M.V., Randolph, G.W., Sacks, B., Garber, J.R. (eds) Handbook of Thyroid and Neck Ultrasonography. Contemporary Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-031-18448-2_7
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DOI: https://doi.org/10.1007/978-3-031-18448-2_7
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