Abstract
Quite by chance, I became aware of Vincent L. Gott MD from an abstract prepared for a Carbon Conference and contacted him, offering test samples of quasi-crystalline carbon structures General Atomic could supply. Test them he did. Consequently, General Atomic was awarded a contract to study its carbon for use in the Artificial Heart Program, a government-funded study. I also participated in an informal Gordon Conference held in Vermont. Our objective was to determine the effect of the crystalline structure, surface chemistry, and surface topography of carbon on the sorptivity of heparin and the carbon’s compatibility with blood. The stage had been set for General Atomic’s entrance to the medical device field.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gott VL, Koepke DE, Daggett RL, et al. The coating of intravascular plastic prostheses with colloidal graphite. Surgery. 1961;50(2):382–9.
Gott VL, Daggett RL, Koepke DE, et al. Replacement of canine pulmonary valve and pulmonary artery with a graphite coated valve prosthesis. J Thorac Cardiovasc Surg. 1962;44(6):713–21.
Gott VL, Whiffen JD, Dutton RD, et al. The anticlot properties of graphite coatings on artificial heart valves. Abstract of paper submitted for presentation at the Sixth American Carbon Conference, Pittsburgh, PA, June 17–21, 1963.
Gott VL, Whiffen JD, Dutton RD. Heparin bonding on colloidal graphite surfaces. Science. 1963;142:1297–8.
Hastings FW, Harmison LT. Proceedings of artificial heart program, National Heart Institute, Hegyeli RJ, editor, June 9–13, 1969.
Bokros JC, Ellis WH. US Patent No 3,526,005, Carbon Medical Implant Devices, issued September 1, 1970.
De Laszlo. US Patent No 3,526,906, issued September 8, 1970.
Bokros JC. US Patent No 3,579,645, Broad Medical Implants, issued May 25, 1971.
Bokros JC. US Patent No 3,676,179, Residual Stress, issued July 11, 1972.
Bokros JC, Ellis WH. US Patent No 3,677,795, PyC Medical Devices, issued July 18, 1972.
Bokros JC, Ellis WH. US Patent No 3,685,059, Medical Devices, issued August 22, 1972.
Bokros JC, Ellis WH. US Patent No 3,707,006, Orthopedic Implant Devices, issued December 26, 1972.
Bokros JC. US Patent No 3,783,868, Percutaneous Device, issued January 8, 1974.
Bokros JC. US Patent No 3,971,134, Dental Implant, issued July 27, 1976.
Bokros JC. US Patent No 4,131,957, Finger Joint, issued January 2, 1979.
Bokros JC, Haubold AD, Akins RJ, et al. Trends in prosthetic heart valve design in. In: Bodnar E, Frater RWM, editors. Replacement cardiac valves. New York: Pergamon Press, Inc; 1991. p. 333–55.
Bokros JC, Haubold AD, Akins RJ, et al. The durability of mechanical heart valve replacements: past experiences and current trends in. In: Bodnar E, Frater RWM, editors. Replacement cardiac valves. New York: Pergamon Press, Inc.; 1991. p. 21–48.
Haubold AD, Bokros JC. Chapter 1: carbon in medical devices. In: Williams DF, editor. Biocompatibility of clinical implant materials, CRC series in biocompatibility, vol. 2. Boca Raton: CRC Press, Inc; 1981. p. 3.
Bokros JC, Gott VL, LaGrange LD, et al. Heparin sorptivity and blood compatibility of carbon surfaces. J Biomed Mater Res. 1970;4:145–87.
LaGrange LD, Gott VL, Bokros JC, et al. Compatibility of carbon and blood. In: Hegyeli RJ, editor. Proceedings of artificial heart program, June 9–13 1969. Washington DC: National Heart Institute; 1969.
Bokros JC, Gott VL, LaGrange LD, et al. Correlations between the blood compatibility and heparin sorptivity for an impermeable, isotropic pyrolytic carbon. J Biomed Mater Res. 1969;3:497–528.
Gott VL, Alejo DE, Cameron DEMD. Mechanical heart valves: 50 years of evolution. Ann Thorac Surg. 2003;76:S2230.
Gott VL, Daggett RL, Young WP. Development of a carbon coated central-hinging bileaflet valve. Ann Thorac Surg. 1989;48:528–30.
Bokros JC. US Patent No 3,546,711, Heart Valve, issued December 15, 1970.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Bokros, J. (2023). Gott’s Early Experience: A Lesson in Serendipity. In: Heart of Carbon . Springer, Cham. https://doi.org/10.1007/978-3-031-17933-4_4
Download citation
DOI: https://doi.org/10.1007/978-3-031-17933-4_4
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-17932-7
Online ISBN: 978-3-031-17933-4
eBook Packages: EngineeringEngineering (R0)