Skip to main content

Defining the High-Risk Surgical Patient

  • Chapter
  • First Online:
The High-risk Surgical Patient

Abstract

The definition of risk in surgical patients is a complex process mainly based on subjective evaluation of the patient’s overall health status by the surgeon and the anaesthesiologist and the type and urgency of the surgical procedure. An objective assessment of risk is essential to guide surgical decision-making, communication within the multidisciplinary team and with the patient and his family, allocation of resources, and improvement of patient outcomes through tailored perioperative care. Different risk prediction tools described in this chapter can be used in the evaluation of surgical risk; in addition, functional capacity, frailty, and the likelihood of perioperative neurocognitive disorders must be taken into account during risk assessment. Accurate and timely identification of high-risk surgical patients, defined by predicted hospital mortality of ≥5%, is required for optimizing their care through improved preoperative evaluation and perioperative management, including advanced haemodynamic monitoring and goal-directed haemodynamic optimization. This chapter aims to summarize the recent advances in perioperative risk stratification, suggesting a practical approach to the assessment of surgical risk.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Pearse RM, Harrison DA, James P, Watson D, Hinds C, Rhodes A, Grounds RM, Bennett ED. Identification and characterisation of the high-risk surgical population in the United Kingdom. Crit Care. 2006;10(3):R81.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Moonesinghe SR, Mythen MG, Das P, Rowan KM, Grocott MP. Risk stratification tools for predicting morbidity and mortality in adult patients undergoing major surgery: qualitative systematic review. Anesthesiology. 2013;119(4):959–81.

    Article  PubMed  Google Scholar 

  3. Bilimoria KY, Liu Y, Paruch JL, Zhou L, Kmiecik TE, Ko CY, Cohen ME. Development and evaluation of the universal ACS NSQIP surgical risk calculator: a decision aid and informed consent tool for patients and surgeons. J Am Coll Surg. 2013;217(5):833–42. e831–3.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Boyd O, Jackson N. Clinical review: how is risk defined in high-risk surgical patient management? Crit Care. 2005;9(4):390.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Royal College of Surgeons of England, Department of Health. The higher risk general surgical patient: towards improved care for a forgotten group. London: RCSE; 2011.

    Google Scholar 

  6. Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. London: RCSE; 2018.

    Google Scholar 

  7. Sankar A, Beattie WS, Wijeysundera DN. How can we identify the high-risk patient? Curr Opin Crit Care. 2015;21(4):328–35.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Finks JF, Osborne NH, Birkmeyer JD. Trends in hospital volume and operative mortality for high-risk surgery. N Engl J Med. 2011;364(22):2128–37.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Bohnen JD, Ramly EP, Sangji NF, de Moya M, Yeh DD, Lee J, Velmahos GC, Chang DC, Kaafarani HM. Perioperative risk factors impact outcomes in emergency versus nonemergency surgery differently: time to separate our national risk-adjustment models? J Trauma Acute Care Surg. 2016;81(1):122–30.

    Article  PubMed  Google Scholar 

  10. Ingraham AM, Cohen ME, Bilimoria KY, Raval MV, Ko CY, Nathens AB, Hall BL. Comparison of 30-day outcomes after emergency general surgery procedures: potential for targeted improvement. Surgery. 2010;148(2):217–38.

    Article  PubMed  Google Scholar 

  11. Ingraham AM, Cohen ME, Bilimoria KY, Feinglass JM, Richards KE, Hall BL, Ko CY. Comparison of hospital performance in nonemergency versus emergency colorectal operations at 142 hospitals. J Am Coll Surg. 2010;210(2):155–65.

    Article  PubMed  Google Scholar 

  12. Becher RD, Hoth JJ, Miller PR, Mowery NT, Chang MC, Meredith JW. A critical assessment of outcomes in emergency versus nonemergency general surgery using the American College of Surgeons National Surgical Quality Improvement Program database. Am Surg. 2011;77(7):951–9.

    Article  PubMed  Google Scholar 

  13. Akinbami F, Askari R, Steinberg J, Panizales M, Rogers SO Jr. Factors affecting morbidity in emergency general surgery. Am J Surg. 2011;201(4):456–62.

    Article  PubMed  Google Scholar 

  14. Havens JM, Peetz AB, Do WS, Cooper Z, Kelly E, Askari R, Reznor G, Salim A. The excess morbidity and mortality of emergency general surgery. J Trauma Acute Care Surg. 2015;78(2):306–11.

    Article  PubMed  Google Scholar 

  15. Saunders DI, Murray D, Pichel AC, Varley S, Peden CJ, Network UKEL. Variations in mortality after emergency laparotomy: the first report of the UK emergency laparotomy Network. Br J Anaesth. 2012;109(3):368–75.

    Article  CAS  PubMed  Google Scholar 

  16. Vester-Andersen M, Lundstrom LH, Moller MH, Waldau T, Rosenberg J, Moller AM, Danish Anaesthesia D. Mortality and postoperative care pathways after emergency gastrointestinal surgery in 2904 patients: a population-based cohort study. Br J Anaesth. 2014;112(5):860–70.

    Article  CAS  PubMed  Google Scholar 

  17. Al-Temimi MH, Griffee M, Enniss TM, Preston R, Vargo D, Overton S, Kimball E, Barton R, Nirula R. When is death inevitable after emergency laparotomy? Analysis of the American College of Surgeons National Surgical Quality Improvement Program database. J Am Coll Surg. 2012;215(4):503–11.

    Article  PubMed  Google Scholar 

  18. Symons NR, Moorthy K, Almoudaris AM, Bottle A, Aylin P, Vincent CA, Faiz OD. Mortality in high-risk emergency general surgical admissions. Br J Surg. 2013;100(10):1318–25.

    Article  CAS  PubMed  Google Scholar 

  19. Association of Coloproctology of Great Britain and Ireland, Royal College of Surgeons of England, Health and Social Care Information Centre. National Bowel Cancer Audit annual report 2017, version 2. London: Health and Social Care Information Centre; 2017.

    Google Scholar 

  20. Saklad M. Grading of patients for surgical procedures. Anesthesiology. 1941;2(3):281–4.

    Article  Google Scholar 

  21. Horvath B, Kloesel B, Todd MM, Cole DJ, Prielipp RC. The evolution, current value, and future of the American Society of Anesthesiologists Physical Status Classification System. Anesthesiology. 2021;135(5):904–19.

    Article  PubMed  Google Scholar 

  22. Knuf KM, Maani CV, Cummings AK. Clinical agreement in the American Society of Anesthesiologists physical status classification. Perioper Med (Lond). 2018;7:14.

    Article  PubMed  Google Scholar 

  23. Koo CY, Hyder JA, Wanderer JP, Eikermann M, Ramachandran SK. A meta-analysis of the predictive accuracy of postoperative mortality using the American Society of Anesthesiologists’ physical status classification system. World J Surg. 2015;39(1):88–103.

    Article  PubMed  Google Scholar 

  24. Bose S, Talmor D. Who is a high-risk surgical patient? Curr Opin Crit Care. 2018;24(6):547–53.

    Article  PubMed  Google Scholar 

  25. Prytherch DR, Whiteley MS, Higgins B, Weaver PC, Prout WG, Powell SJ. POSSUM and Portsmouth POSSUM for predicting mortality. Physiological and operative severity score for the enumeration of mortality and morbidity. Br J Surg. 1998;85(9):1217–20.

    Article  CAS  PubMed  Google Scholar 

  26. Gawande AA, Kwaan MR, Regenbogen SE, Lipsitz SA, Zinner MJ. An Apgar score for surgery. J Am Coll Surg. 2007;204(2):201–8.

    Article  PubMed  Google Scholar 

  27. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, Sugarbaker DJ, Donaldson MC, Poss R, Ho KK, Ludwig LE, Pedan A, Goldman L. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100(10):1043–9.

    Article  CAS  PubMed  Google Scholar 

  28. Fleisher LA, Fleischmann KE, Auerbach AD, Barnason SA, Beckman JA, Bozkurt B, Davila-Roman VG, Gerhard-Herman MD, Holly TA, Kane GC, Marine JE, Nelson MT, Spencer CC, Thompson A, Ting HH, Uretsky BF, Wijeysundera DN, American College of Cardiology/American Heart Association. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. J Am Coll Cardiol. 2014;64(22):e77–137.

    Article  PubMed  Google Scholar 

  29. Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Ambosta A, Croal BL, Granton JT, Thorpe KE, Grocott MPW, Farrington C, Myles PS, Cuthbertson BH. Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study. Lancet. 2018;391(10140):2631–40.

    Article  PubMed  Google Scholar 

  30. Levett DZH, Jack S, Swart M, Carlisle J, Wilson J, Snowden C, Riley M, Danjoux G, Ward SA, Older P, Grocott MPW, Perioperative Exercise T, Training S. Perioperative cardiopulmonary exercise testing (CPET): consensus clinical guidelines on indications, organization, conduct, and physiological interpretation. Br J Anaesth. 2018;120(3):484–500.

    Article  CAS  PubMed  Google Scholar 

  31. Biccard BM, Devereaux PJ, Rodseth RN. Cardiac biomarkers in the prediction of risk in the non-cardiac surgery setting. Anaesthesia. 2014;69(5):484–93.

    Article  CAS  PubMed  Google Scholar 

  32. Beggs T, Sepehri A, Szwajcer A, Tangri N, Arora RC. Frailty and perioperative outcomes: a narrative review. Can J Anaesth. 2015;62(2):143–57.

    Article  PubMed  Google Scholar 

  33. Bierle DM, Raslau D, Regan DW, Sundsted KK, Mauck KF. Preoperative evaluation before noncardiac surgery. Mayo Clin Proc. 2020;95(4):807–22.

    Article  PubMed  Google Scholar 

  34. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP. Surviving sepsis campaign: international guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. 2017;43(3):304–77.

    Article  PubMed  Google Scholar 

  35. Aseni P, Orsenigo S, Storti E, Pulici M, Arlati S. Current concepts of perioperative monitoring in high-risk surgical patients: a review. Patient Saf Surg. 2019;13:32.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Futier E, Lefrant JY, Guinot PG, Godet T, Lorne E, Cuvillon P, Bertran S, Leone M, Pastene B, Piriou V, Molliex S, Albanese J, Julia JM, Tavernier B, Imhoff E, Bazin JE, Constantin JM, Pereira B, Jaber S. Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery: a randomized clinical trial. JAMA. 2017;318(14):1346–57.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee TS. Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest. 1988;94(6):1176–86.

    Article  CAS  PubMed  Google Scholar 

  38. Giglio M, Dalfino L, Puntillo F, Rubino G, Marucci M, Brienza N. Haemodynamic goal-directed therapy in cardiac and vascular surgery. A systematic review and meta-analysis. Interact Cardiovasc Thorac Surg. 2012;15(5):878–87.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Cecconi M, Corredor C, Arulkumaran N, Abuella G, Ball J, Grounds RM, Hamilton M, Rhodes A. Clinical review: goal-directed therapy-what is the evidence in surgical patients? The effect on different risk groups. Crit Care. 2013;17(2):209.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Leiner T, Tánczos K, Molnar Z. Avoiding perioperative oxygen debt. J Emerg Crit Care Med. 2019;4:6.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lucrezia Rovati .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Rovati, L., Arlati, S., Aseni, P. (2023). Defining the High-Risk Surgical Patient. In: Aseni, P., Grande, A.M., Leppäniemi, A., Chiara, O. (eds) The High-risk Surgical Patient. Springer, Cham. https://doi.org/10.1007/978-3-031-17273-1_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-17273-1_1

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-17272-4

  • Online ISBN: 978-3-031-17273-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics