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Dendrimers in Malaria

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Malarial Drug Delivery Systems

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Abstract

Malaria is a widespread well-known disease, causing many mortalities still today. Many drug therapies are available for the treatment of the disease, but still the scope for improvement is available. Nanocarriers indicate vast scope for research in antimalarial therapy. Dendrimers are one of the novel approaches in the everlasting research for antimalarial therapy. Dendrimers are largely branched, monodisperse macromolecules, which are having a structural perfection. Their surface and core are used to carry drug molecules along with them to the targeted delivery site. Many antimalarial drugs like chloroquine, primaquine, etc. are studied by conjugating with the dendrimers for their antimalarial properties along with the various formulation properties. They have been studied for the drug pharmacokinetic profiles, dose frequency and drug toxicity.

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Authors and Affiliations

  1. Arihant School of Pharmacy and Bio Research Institute, Gandhinagar, Gujarat, India

    Chaudhary Sunita

  2. Department of Pharmaceutics, C. U. Shah college of Pharmacy & Research, Surendranagar, Gujarat, India

    Khodakiya Akruti

  3. Saraswati Institute of Pharmaceutical Sciences, Dhanap, Gandhinagar, Gujarat, India

    Chaudhary Ankit

  4. Nootan Pharmacy College, Sankalchand Patel University, Visnagar, Gujarat, India

    Jayvadan K. Patel

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  2. Khodakiya Akruti
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  3. Chaudhary Ankit
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  4. Jayvadan K. Patel
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Editors and Affiliations

  1. CapnoPharm GmbH, Tübingen, Germany

    Ranjita Shegokar

  2. Taneja College of Pharmacy, University of South Florida, Florida, USA

    Yashwant Pathak

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Sunita, C., Akruti, K., Ankit, C., Patel, J.K. (2023). Dendrimers in Malaria. In: Shegokar, R., Pathak, Y. (eds) Malarial Drug Delivery Systems. Springer, Cham. https://doi.org/10.1007/978-3-031-15848-3_7

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