Abstract
Global population is estimated to increase by 25% and reach 10 billion over the next 30 years. Conventional breeding methods have thus far produced crops with enhanced nutritional status and high yields to meet the food requirements of the growing population. But the current pace of yield increase for major crops, including rice (Oryza sativa), wheat (Triticum aestivum), and maize (Zea mays), is insufficient to meet future demand. A major limitation for plant breeding and crop improvement, the time-consuming crop production approaches, which in general allow only one or two generations per year, have been advanced by “speed breeding” (SB) by reducing the breeding cycle and accelerating crop research through speedy generation advancement. Genome editing has been exploited with the promise of developing new crops in less time with a very low possibility of off-target effects and can be achieved in any laboratory with any crop, even those with complex genomes. However, gene editing still entails time-consuming tissue culture, in addition to specialized labs with a level of physical containment appropriate for undertaking genetic manipulation using CRISPR reagents. Systems that integrate gene editing directly with a SB platform, for instance, ExpressEDIT could avoid the barriers of in vitro manipulation of plant materials. Though not yet routine, several steps are operational on the way to fast-tracking genome editing to breed better crop varieties which are highlighted in the present chapter. Integrating state-of-the-art technologies such as genome editing with SB could enable plant breeders to meet the food security challenges of feeding a growing population of 10 billion.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Achigan-Dako, E. G., Sogbohossou, O. E., & Maundu, P. (2014). Current knowledge on Amaranthus spp.: Research avenues for improved nutritional value and yield in leafy amaranths in sub-Saharan Africa. Euphytica, 197, 303–317.
Action Against Hunger International Nutrition Security Policy, p. 8.
Agapito-Tenfen, S. Z. (2016). Biosafety aspects of genome-editing techniques. Biosafety briefing, ACB and TWN.
Ali, Z., Shami, A., Sedeek, K., Kamel, R., Alhabsi, A., Tehseen, M., Hassan, N., Butt, H., Kababji, A., Hamdan, S. M., & Mahfouz, M. M. (2020). Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice. Communications Biology, 3, 44.
Brookes, G., & Barfoot, P. (2018). Environmental impacts of genetically modified (GM) crop use 1996–2016: Impacts on pesticide use and carbon emissions. GM Crops & Food, 9(3), 109–139.
Chiurugwi, T., Kemp, S., Powell, W., Hickey, L. T., & Powell, W. (2018). Speed breeding orphan crops. Theoretical and Applied Genetics.
Collard, B. C. Y., Beredo, J. C., Lenaerts, B., Mendoza, R., Santelices, R., Lopena, V., Verdeprado, H., Raghavan, C., Gregorio, G. B., Vial, L., et al. (2017). Revisiting rice breeding methods–evaluating the use of rapid generation advance (RGA) for routine rice breeding. Plant Production Science, 20, 337–352.
FAO. (2016). International symposium on the role of biotechnologies in sustainable food systems and nutrition. www.fao.org/about/meetings/agribiotechssymposium/faqs/en
Hartley, S., Gillund, F., van Hove, L., & Wickson, F. (2016). Essential features of responsible governance of agricultural biotechnology. PLoS Biology, 14(5), e1002453.
Johnston, H. R., Keats, B. J. B., & Sherman, S. L. (2019). Population genetics. In R. E. Pyeritz, B. R. Korf, & W. W. Grody (Eds.), Emery and Rimoin’s principles and practice of medical genetics and genomics. Foundations (pp. 359–373). Academic. https://doi.org/10.1016/B978-0-12-812537-3.00012-3
Kangmennaang, J., Osei, L., Armah, F. A., & Luginaah, I. (2016). Genetically modified organisms and the age of (un) reason? A critical examination of the rhetoric in the GMO public policy debates in Ghana. Futures, 83, 37–49.
Lacchini, E., Kiegle, E., Castellani, M., Adam, H., Jouannic, S., Gregis, V., & Kater, M. M. (2020). CRISPR-mediated accelerated domestication of African rice landraces. PLoS One, 15(3), e0229782.
Lu, Y., & Zhu, J.-K. (2017). Precise editing of a target base in the rice genome using a modified CRISPR/Cas9 system. Molecular Plant, 10(3), 523–525.
Morris, M. L., & Bellon, M. R. (2004). Participatory plant breeding research: Opportunities and challenges for the international crop improvement system. Euphytica, 136(1), 21–35. https://doi.org/10.1023/B:EUPH.0000019509.37769.b1
Nekrasov, V., Staskawicz, B., Weigel, D., Jones, J. D. G., & Kamoun, S. (2013). Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease. Nature Biotechnology, 31, 691.
Oliva, R., Ji, C., Atienza-Grande, G., Huguet-Tapia, J. C., Perez-Quintero, A., Li, T., Eom, J.-S., Li, C., Nguyen, H., Liu, B., Auguy, F., Sciallano, C., Luu, V. T., Dossa, G. S., Cunnac, S., Schmidt, S. M., Slamet-Loedin, I. H., Vera Cruz, C., Szurek, B., Frommer, W. B., White, F. F., & Yang, B. (2019). Broad-spectrum resistance to bacterial blight in rice using genome editing. Nature Biotechnology, 37(11), 1344–1350.
SAM. (2017). New techniques in agricultural biotechnology. E.C.H.L.G.o.t.S.A. Mechanism. Publications Office of the European Union.
Shi, J., Gao, H., Wang, H., Lafitte, H. R., Archibald, R. L., Yang, M., Hakimi, S. M., Mo, H., & Habben, J. E. (2017). ARGOS 8 variants generated by CRISPR-Cas9 improve maize grain yield under field drought stress conditions. Plant Biotechnology Journal, 15(2), 207–216.
Shimelis, H., Gwata, E. T., & Laing, M. D. (2019). Crop improvement for agricultural transformation in Southern Africa. In R. A. Sikora, E. R. Terry, P. L. G. Vlek, & J. Chitja (Eds.), Transforming agriculture in Southern Africa (1st ed., pp. 97–103). Routledge. https://doi.org/10.4324/9780429401701
Singer, M. F. (1979). Introduction and historical background. In J. K. Setlow & A. Hollaender (Eds.), Genetic engineering (Vol. 1, pp. 1–13). Plenum.
Slama-Ayed, O., Bouhaouel, I., Ayed, S., De Buyser, J., Picard, E., & Amara, H. S. (2019). Efficiency of three haplo-methods in durum wheat (Triticum turgidum subsp. durum Desf.): Isolated microspore culture, gynogenesis and wheat× maize crosses. Czech Journal of Genetics and Plant Breeding, 55, 101–109.
Sustainable Development Goal 2, Zero Hunger. https://sustainabledevelopment.un.org/sdg2
Wang, Y., Cheng, X., Shan, Q., Zhang, Y., Liu, J., Gao, C., & Qiu, J.-L. (2014). Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotechnology, 32(9), 947–951.
Wang, F., Wang, C., Liu, P., Lei, C., Hao, W., Gao, Y., Liu, Y.-G., & Zhao, K. (2016). Enhanced rice blast resistance by CRISPR/Cas9-targeted mutagenesis of the ERF transcription factor gene OsERF922. PLoS One, 11(4), e0154027.
Watson, A., Ghosh, S., Williams, M. J., Cuddy, W. S., Simmonds, J., Rey, M. D., Hatta, A. M., Hinchliffe, A., Steed, A., Reynolds, D., & Hickey, L. T. (2018). Speed breeding is a powerful tool to accelerate crop research and breeding. Nature Plants, 4, 23–29.
Wieczorek, A. M., & Wright, M. G. (2012). History of agricultural biotechnology: How crop development has evolved. Nature Education Knowledge, 3(10), 9.
Xie, K., Zhang, J., & Yang, Y. (2014). Genome-wide prediction of highly specific guide RNA spacers for CRISPR-Cas9-mediated genome editing in model plants and major crops. Molecular Plant, 7(5), 923–926.
Zeng, Y., Wen, J., Zhao, W., Wang, Q., & Huang, W. (2020). Rational improvement of rice yield and cold tolerance by editing the three genes OsPIN5b, GS3, and OsMYB30 with the CRISPR−Cas9 system. Frontiers in Plant Science, 10, 1663.
Zhang, Z., Mao, Y., Ha, S., Liu, W., Botella, J. R., & Zhu, J. K. (2016). A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis. Plant Cell Reports, 35, 1519–1533.
Zhang, Q., Xing, H.-L., Wang, Z.-P., Zhang, H.-Y., Yang, F., Wang, X.-C., & Chen, Q.-J. (2018). Potential high-frequency off-target mutagenesis induced by CRISPR/Cas9 in Arabidopsis and its prevention. Plant Molecular Biology, 96(4–5), 445–456.
Zhao, H., & Wolt, J. D. (2017). Risk associated with off-target plant genome editing and methods for its limitation. Emerging Topics in Life Sciences, 1(2), 231–240.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Hussain, K., Mahrukh, Nisa, R.T., Zaid, A., Mushtaq, M. (2023). The Utilization of Speed Breeding and Genome Editing to Achieve Zero Hunger. In: Prakash, C.S., Fiaz, S., Nadeem, M.A., Baloch, F.S., Qayyum, A. (eds) Sustainable Agriculture in the Era of the OMICs Revolution. Springer, Cham. https://doi.org/10.1007/978-3-031-15568-0_1
Download citation
DOI: https://doi.org/10.1007/978-3-031-15568-0_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-15567-3
Online ISBN: 978-3-031-15568-0
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)